A5055190046- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Neuroscience and Neural Engineering
- Wireless Power Transfer Systems
- Advanced Sensor and Energy Harvesting Materials
- Cardiac Structural Anomalies and Repair
- Electrostatic Discharge in Electronics
- Cardiomyopathy and Myosin Studies
- Neurological disorders and treatments
- Innovative Energy Harvesting Technologies
- Wireless Body Area Networks
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Energy Harvesting in Wireless Networks
- Non-Invasive Vital Sign Monitoring
- Cardiac Imaging and Diagnostics
- Analog and Mixed-Signal Circuit Design
- Coronary Artery Anomalies
- Cardiovascular Syncope and Autonomic Disorders
- Optical Coherence Tomography Applications
- CRISPR and Genetic Engineering
- Hemodynamic Monitoring and Therapy
University of Bern
2016-2025
University Hospital of Bern
2016-2025
Swissmedic
2022-2023
Medical University of Vienna
2022
Electrophysiology and Heart Modeling Institute
2019-2020
Centre Hospitalier Universitaire de Bordeaux
2018-2020
Hôpital Cardiologique du Haut-Lévêque
2018-2019
Université de Bordeaux
2019
University of Milan
2018
University of Copenhagen
2018
BACKGROUND Contemporary pacemakers (PMs) are powered by primary batteries with a limited energy-storing capacity.PM replacements because of battery depletion common and unpleasant bear the risk complications.Batteryless PMs that harvest energy inside body may overcome these limitations.OBJECTIVE The goal this study was to develop batteryless PM solar module converts transcutaneous light into electrical energy.METHODS Ex vivo measurements were performed modules placed under pig skin flaps...
The left atrial posterior wall is a potential ablation target in patients with recurrent fibrillation despite durable pulmonary vein isolation or roof-dependent tachycardia (AT). Pulsed-field (PFA) offers efficient and safe (PWA), but available data are scarce.
Pulmonary vein isolation (PVI) is increasingly performed in patients with atrial fibrillation (AF). Both AF phenotype and left (LA) volume have been shown to influence ablation outcome. The inter-relationship of the two incompletely understood. We aimed investigate impact vs. LA on outcome after PVI.
Today's cardiac pacemakers are powered by batteries with limited energy capacity. As the battery's lifetime ends, pacemaker needs to be replaced. This surgical re-intervention is costly and bears risk of complications. Thus, a without primary desirable. The goal this study was test whether transcutaneous solar light could power pacemaker.We used three-step approach investigate feasibility sunlight-powered pacing. First, harvestable estimated. Theoretically, subcutaneously implanted 1 cm(2)...
A new pseudo asynchronous level crossing analogue-to-digital converter (adc) architecture targeted for low-power, implantable, long-term biomedical sensing applications is presented. In contrast to most of the existing adc designs, proposed design has no digital-to-analogue (dac) and continuous time comparators. Instead, uses an analogue memory cell dynamic The retains signal activity dependent sampling operation by generating events only when input changing. offers advantages smaller chip...
Leadless pacemakers (PMs) capable of atrioventricular (AV) synchronous pacing have recently been introduced. Initial feasibility studies were promising but limited to just a few minutes AV pacing. Real-world, long-term data on synchrony and programming adjustments affecting in outpatients are lacking.The purpose this study was investigate influences PM with leadless VDD PMs.All patients who received (Micra™ AV, Medtronic) between July 2020 May 2021 at our center included observational study....
Abstract Background Pulsed-field ablation (PFA) has shown favourable data in terms of safety and procedural efficiency for pulmonary vein isolation (PVI). We sought to compare 1-year follow-up patients with paroxysmal atrial fibrillation (AF) undergoing PVI using PFA, cryoballoon (CBA) radiofrequency (RFA). Methods Consecutive AF a first PFA at our institution were included. For comparison, CBA RFA selected 1:2:2 propensity score matching. The group followed the standard 32-applications...
Abstract Background and Aims The European Union Medical Device Regulation 2017/745 challenges key stakeholders to follow transparent rigorous approaches the clinical evaluation of medical devices. purpose this study is a systematic published evidence underlying selected high-risk cardiovascular devices before after market access in (CE-marking) between 2000 2021. Methods Pre-specified strategies were applied identify studies prospective design evaluating 71 seven different classes...
To validate the performance of a multipolar pulsed-field ablation (PFA) catheter compared to standard pentaspline 3D-mapping for endpoint assessment pulmonary vein isolation (PVI). PFA PVI using single-shot devices combines benefits high procedural efficacy and safety. A newly available allows real-time recording (PV) signals during PVI.Patients undergoing first with protocol (eight applications per PV) were studied. Entrance exit block (10 V/2 ms) assessed catheter. Subsequently,...
Background The association of epicardial adipose tissue (EAT) and its metabolic activity with atrial fibrillation (AF) is an area active investigation. Left (LA) enhancing EAT (e-EAT) at cardiac CT may be a noninvasive surrogate marker for the EAT. Purpose To determine relationship between LA e-EAT recurrence after AF ablation. Materials Methods In secondary analysis prospective registry consecutive patients (from July 2018 to December 2019) undergoing first ablation, total were segmented on...
Abstract Background A novel multipolar pulsed-field ablation (PFA) catheter has recently been introduced for pulmonary vein isolation (PVI). Pre-market data showed high rates PVI-durability during mandatory remapping studies. Objective : To present post-market in patients with recurrent arrhythmias. Methods Consecutive undergoing a redo procedure after an index PFA PVI using bipolar-biphasic system were included. 3-D electro-anatomical maps (3D-EAM) on compared to the 3D-EAM acquired...
Contemporary leadless pacemakers only feature single-chamber pacing capability. This study presents a prototype of dual-chamber pacemaker. Highly energy-efficient intrabody communication was implemented for wireless pacemaker synchronization. Optimal parameters were obtained by in vivo and ex measurements the heart blood. The successfully performed vivo. presented method may future also enable cardiac resynchronization therapy.
Active electronic implants are powered by primary batteries, which induces the necessity of implant replacement after battery depletion. This causes repeated interventions in a patients' life, bears risk complications and is costly. By using energy harvesting devices to power implant, device replacements may be avoided size reduced dramatically. Recently, several groups presented prototypes subcutaneous solar cells. However, data about expected real-life output subcutaneously implanted cells...
cardiac pacemakers require regular medical follow-ups to ensure proper functioning. However, device replacements due battery depletion are common and account for ∼25% of all implantation procedures. Furthermore, conventional pacemaker leads which prone fractures, dislocations or isolation defects. The ensuing surgical interventions increase risks the patients costs that need be avoided.in this study, we present a method harvest energy from endocardial heart motions. We developed novel...
Energy harvesting devices are widely discussed as an alternative power source for todays active implantable medical devices. Repeated battery replacement procedures can be avoided by extending the implants life span, which is goal of energy concepts. This reduces risk complications patient and may even reduce device size. The continuous powerful contractions a human heart ideally qualify substitute. In particular, in close proximity to such pacemakers, defibrillators or bio signal (ECG)...
Subdermal solar harvesting has the potential to obviate need for periodic battery replacements as required in patients with cardiac pacemakers. The achievable power output of subdermal module depends on implantation depth, optical skin properties and an important part cell characteristics. Monte Carlo simulations light distribution human were used estimate cells under midday sunlight exposure geographical mid-latitudes a function depth panel size. For darkest type, daily energy demand modern...
We describe our initial experience using a multipolar pulsed-field ablation catheter for the treatment of left atrial (LA) reentry tachycardia.We included all patients with LA tachycardia treated PFA at institution between September 2021 and March 2022. The mechanism was identified 3D electro-anatomical mapping (3D-EAM). Subsequently, roof line, anterior or mitral isthmus line ablated as appropriate. Roof always combined posterior wall (LAPW) ablation. Positioning guided by 3D-EAM system...
Abstract Objectives Epicardial adipose tissue (EAT) remodeling is associated with atrial fibrillation (AF). Left (LA) EAT dispersion on cardiac CT a non-invasive imaging biomarker reflecting heterogeneity. We aimed to investigate the association of LA AF recurrence after pulmonary vein isolation (PVI). Methods In prospective registry consecutive patients undergoing first PVI, mean attenuation values were measured contrast-enhanced scans in Hounsfield units (HU) within low (− 195 − 45 HU) and...