A5103111393- Seaweed-derived Bioactive Compounds
- Algal biology and biofuel production
- Marine and coastal plant biology
- Marine Sponges and Natural Products
- Microbial Metabolites in Food Biotechnology
- Polysaccharides and Plant Cell Walls
- Echinoderm biology and ecology
- Microbial Natural Products and Biosynthesis
- Food Industry and Aquatic Biology
- Bioactive Compounds and Antitumor Agents
- Bioactive natural compounds
- Biochemical Acid Research Studies
- Cancer Research and Treatments
- Enzyme Production and Characterization
- Therapeutic Uses of Natural Elements
- Phytochemical and Pharmacological Studies
- Moringa oleifera research and applications
- Free Radicals and Antioxidants
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Cancer Cells and Metastasis
- Phytochemical Studies and Bioactivities
- Synthetic Organic Chemistry Methods
- Biochemical effects in animals
Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences
2011-2025
Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences
2012-2017
Russian Academy of Sciences
2011-2013
Brown alga Fucus evanescens, widespread in the Far Eastern seas of Russia, is valuable source sulfated polysaccharides – fucoidans with beneficial biological activities. The most homogenous fraction fucoidan from F. evanescens was shown to be molecule containing linear main chain alternating 2-sulfated 1,3- and 1,4-linked α-L-fucose residues. Few sulfate groups were found position 4 some 1,3-linked fucose Acetyl occupied free C-3 residues and/or C-4 Enzymatic hydrolysis, mild acid hydrolysis...
Abstract Structural characteristics and the antitumor activity of fucoidans isolated from vegetative reproductive tissue brown algae Alaria sp. Saccharina japonica were studied. The status affected yield their structural characteristics. fucoidan was 5.7% ( w / on basis dried weight) for fertile 3.8% sterile 1.42 0.71% S. , respectively. had a slightly higher degree sulfation somewhat more homogeneous monosaccharide composition, with predominate amounts fucose galactose, than those tissue....
Objective. To study the effect of fucoidan from brown algae S. feldmannii (SfF2) on metabolism MDA-MB-231 breast cancer cells. Materials and methods. The bioenergetic potential cells was assessed under influence various factors (insulin, epidermal growth factor, phorbol ester, X-rays) stimulating tumor progression. metabolically oriented SfF2 (200 µg/ml) colony formation process human determined using soft agar method normal conditions carcinogenic factors. Results. Fucoidan found to reduce...
α-
Two new polyhydroxysteroidal glycosides, anthenosides A1 (1) and A2 (2), one previously known steroidal glycoside anthenoside A (3) were isolated from extract of the tropical starfish Anthenea aspera. Structures 1–3 determined by analysis spectroscopic data as well chemical transformations. As a result, structure has been revised structures 1 2 established. Glycosides contain 2-acetamido-2-deoxy-4-O-methyl-β-d-glucopyranosyl residue, found in glycosides for first time. All compounds slightly...