A5102742304- Autopsy Techniques and Outcomes
- Healthcare cost, quality, practices
- Global Cancer Incidence and Screening
- Forensic Entomology and Diptera Studies
- Glioma Diagnosis and Treatment
- Forensic Anthropology and Bioarchaeology Studies
- Reconstructive Facial Surgery Techniques
- Renal cell carcinoma treatment
- Pediatric Urology and Nephrology Studies
- Healthcare Policy and Management
- Restraint-Related Deaths
- Kidney Stones and Urolithiasis Treatments
- Ureteral procedures and complications
- Public Health Policies and Education
- Traumatic Brain Injury and Neurovascular Disturbances
- Microtubule and mitosis dynamics
- Glycosylation and Glycoproteins Research
- Facial Nerve Paralysis Treatment and Research
- Genital Health and Disease
- Cancer Genomics and Diagnostics
- Advanced Radiotherapy Techniques
- Facial Rejuvenation and Surgery Techniques
- Fetal and Pediatric Neurological Disorders
- Medical Imaging Techniques and Applications
- Tumors and Oncological Cases
Maastricht University Medical Centre
2003-2023
Netherlands Forensic Institute
2018-2020
Abstract Autopsy rates are declining, while major discrepancies between autopsies and clinical diagnoses remain. Still, little is known about the impact of suspected underlying diseases, for example, a diagnosis cancer, on autopsy rate. The aim this study was to investigate relation cause death, history medical rate using data from Netherlands Cohort Study Diet Cancer (NLCS), large prospective cohort with long follow-up. NLCS initiated in 1986 includes 120,852 persons (58,279 males 62,573...
To investigate whether virtual autopsy with postmortem CT (PMCT) improves clinical diagnosis of the immediate cause death.Retrospective observational cohort study.inhospital and out-of-hospital deaths over age 1 year in whom PMCT conventional were performed.forensic cases, postmortal organ donors cases incomplete scanning procedures. Cadavers examined by prior to autopsy. The clinically determined death was recorded before then adjusted findings Using as reference standard, we investigated...
Cutaneous metastases of internal malignancies occur in 1-10% cancer patients. The diagnosis can sometimes be challenging, especially cases with an unknown primary cancer.A retrospective case review was performed including all skin from diagnosed at the Department Pathology Maastricht University Medical Centre+ 2007 to 2021. clinicopathological data were collected and immunohistochemical molecular diagnostic tests confirm origin metastases.We identified 152 (71 female; 31 male patients)...
Abstract Background Autologous facial fat grafting has gained popularity in recent years and is considered to be safe. This paper presents the case of a patient who died due massive cerebral microfat embolism after grafting. Objectives The aim this study was raise awareness provide more evidence on prevention treatment potentially lethal complication Methods A detailed report made case. Two online databases were searched for similar cases resulting neurologic and/or visual symptoms....
Iatrogenic ureteric injury remains a risk in laparoscopic pelvic procedures. Near-infrared fluorescence (NIRF) imaging is promising new technique for enhanced intraoperative visualization of anatomical structures that could improve the safety surgery. A dye, IRDye® 800-BK, has been developed ureters using NIRF. The present study was first evaluation performance 800-BK during NIRF laparoscopy. This consisted three parts: real-time vivo pigs surgery, ex freshly explanted pig and human ureters....
The proof of abusive head trauma (AHT) in infants is difficult, especially cases with a long posttraumatic survival period. In the acute phase, injury to cranio-cervical junction causes disturbances respiratory and cardiac control, leading apnea bradycardia. Infants who survive phase may subsequently develop multicystic encephalopathy. Because some types changes are age-dependent, examination patterns brain damage these could provide information about time which they were inflicted....
Aim The aim of this implementation study was to assess the effect postmortem CT (PMCT) and sampling (PMS) on (traditional) autopsy examination rates. Additionally, feasibility PMCT PMS in daily practice assessed. Methods For a period 23 months, were used as additional modalities at Department Internal Medicine. next kin provided consent for 123 examinations. Autopsy rates derived from Dutch Pathology Registry, calculated before, during after period, exclusion rate, table time, time interval...
Background and objective: The current literature describing the use of minimally invasive autopsy in clinical care is mainly focused on cause death. However, identification unexpected findings equally important for evaluation improvement daily care. purpose this study was to analyze post-mortem computed tomography (PMCT) hospitalized patients assess their relevance. Materials methods: This observational included admitted internal medicine ward. Consent PMCT requested from next kin. Decedents...
Aims The aim of this study is to evaluate whether agreement with autopsy-determined cause death (COD) increases by use postmortem CT (PMCT) or PMCT in combination sampling (PMS), when compared clinical assessment only. Methods This prospective observational included deceased patients from the intensive care unit and internal medicine wards between October 2013 August 2017. primary outcome was percentage on COD reference standard (autopsy) alternative examinations (clinical vs PMCT+PMS). In...
The clinical course of astrocytoma grade II (AII) is highly variable and not reflected by histological characteristics. As one the best prognostic factors, higher age identifies rapid progressive A II. For patients over 35 years age, an aggressive treatment normally propagated. under years, there no clear guidance for choices, therefore also necessity histopathological diagnosis often questioned. We studied additional value proliferation index detection genetic aberrations with tumour...
Abstract In the literature, it has been suggested that loss of 10q25‐26 region, including DMBT1 gene (10q25.3), is correlated with initiation and/or malignant progression astrocytomas, although results studies on heterozygosity led to this assumption are not unequivocal. For reason, using double‐target fluorescence in situ hybridization, we compared copy number changes 10q25.3 those pericentromeric region (10q12) 10 cases each astrocytoma grades II and IV. The same specimens were analyzed...