A5100625315- Wound Healing and Treatments
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Schizophrenia research and treatment
- Neural dynamics and brain function
- Heart Rate Variability and Autonomic Control
- Resilience and Mental Health
- Reconstructive Surgery and Microvascular Techniques
- Organ Transplantation Techniques and Outcomes
- Mental Health Treatment and Access
- COVID-19 and Mental Health
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neuroendocrine Tumor Research Advances
- Esophageal and GI Pathology
- EEG and Brain-Computer Interfaces
- Lung Cancer Research Studies
- Memory and Neural Mechanisms
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Nausea and vomiting management
- Action Observation and Synchronization
- Long-Term Effects of COVID-19
- Glutathione Transferases and Polymorphisms
- Viral gastroenteritis research and epidemiology
Anhui Medical University
2008-2025
Hangzhou Seventh Peoples Hospital
2006-2025
Zhejiang University
2010-2025
Chinese Academy of Sciences
2024-2025
Hefei Institutes of Physical Science
2024-2025
Ruian People's Hospital
2023
Wenzhou Medical University
2023
ZheJiang Institute For Food and Drug Control
2019-2022
Hanzhong People's Hospital
2020
Roche (China)
2018
RG7834 is a potent, orally bioavailable small‐molecule inhibitor of hepatitis B virus (HBV) gene expression that belongs to the dihydroquinolizinone (DHQ) chemical class and uniquely blocks production both viral DNA antigens. In this study, we used DHQ compounds as tools in compound‐based adaptation version yeast three‐hybrid screen identify cognate cellular protein targets, non‐canonical poly(A) RNA polymerase associated domain containing proteins 5 7 (PAPD5 PAPD7). Interaction with was...
To control the waterborne transmission of enterovirus 71(EV71), which is associated with hand foot and mouth disease (HFMD), it essential to know inactivation effectiveness disinfectants on EV71 in water. In this article, we present a comparative analysis effects following exposure chlorine dioxide (ClO2) under different doses, pH, temperature conditions. We show that exhibited strong resistance ClO2 (more than MS2 standard) Ct value ranges required for 4-log reduction buffered, disinfectant...
Background Social cognition and interaction training (SCIT) is a psychosocial intervention program for patients with psychosis, designed to improve their social functioning by improving cognition. Although the feasibility efficacy of SCIT have been verified, schizophrenia tend suffer from motivational deficits low treatment adherence. It has suggested that using virtual reality (VR) technology might be effective in addressing these issues. In this study, we aimed develop VR-based compare its...
Small cell lung cancer (SCLC) is a highly malignant neuroendocrine tumor. Platinum-based chemo-resistance the major issue for treatment of SCLC. The objective study to identify drugs that enhance anti-tumor activity cisplatin (CDDP) in Firstly, by high-throughput drug screening, we found disulfiram (DSF), FDA-approved used treat alcohol addiction, was able sensitize CDDP-induced apoptosis RNA-seq analysis revealed cystathionine β-synthase (CBS) potential target combination DSF and CDDP...
We investigated alterations in impulsive choice and action among individuals with methamphetamine use disorder (MUD) compared to a control group after exposure cues associated (METH). Thirty-four participants MUD 31 healthy were instructed experience METH-related virtual reality (VR) social environment perform the go/no-go task as well balloon analog risk (BART) before (the baseline condition) cue-induced watching VR video. There no significant differences between groups for both condition...
Endoscopic dilation of esophageal strictures is a commonly performed procedure in the management dysphagia. The usually done with fluoroscopic guidance. aim this study was to assess use Tracer guide wire conjunction Savary-Gilliard dilators tight without fluoroscopy.Fifty-five patients significant dysphagia from due variety causes were dilated endoscopically. consisted two parts. First, guidewire passed using endoscopic guidance, and then, fluoroscopy. A modified employed particularly...
Suicide among college students is a significant public health concern in China. While suicidal ideation serves as crucial predictor of subsequent plans and behaviors, it important to recognize that most instances may only be fleeting thoughts do not progress an actual plan. Therefore, imperative identify the factors associated with transition from concrete Consequently, this study aims investigate whether certain frequently cited can differentiate individuals who have formulated specific...
Cue-induced craving is widely considered to be the most important risk factor for relapse during abstinence from methamphetamine (Meth). There limited research regarding electroencephalography (EEG) microstates of Meth-dependent patients under exposure drug-related cues. Our objective was investigate whether EEG microstate temporal characteristics could capture neural correlates cue-induced Meth in virtual reality (VR) environments.EEG recordings 35 and 30 healthy controls (HCs) were...
Abstract Background Previous studies have indicated that the temporal lobe is involved in theory of mind (ToM). However, little attention has been paid to ToM patients with cerebral infarction. In this study, we investigated ability infarction (TLCI) using a variety tests. Methods 19 TLCI and 20 healthy controls (HC) were examined Recognition faux pas Reading Mind Eyes (RME) tasks, assess their ToM. Results The results study group performed significantly worse compared HC as revealed total...
This study explored the feasibility of using EEG gamma-band (30-49 Hz) power as an index cue-elicited craving in METH-dependent individuals.Twenty-nine participants dependent on methamphetamine (METH) and 30 healthy were instructed to experience a METH-related virtual reality (VR) social environment.Individuals with METH dependence showed significantly stronger self-reported higher gamma VR environment than individuals. In group, elicited significant increase compared resting state. The...
Certain genetic polymorphisms can lead to differences in immunity function, resulting different clinical outcomes for hepatitis B virus (HBV) patients. The aim of this study was investigate the association between apolipoprotein E (ApoE) gene and HBV infection status northern Chinese individuals.Genomic DNA extracted using an improved sodium iodide (NaI) method from peripheral blood 270 patients with 112 healthy controls. Multiplex Amplification Refractory Mutation System (Multi-ARMS)...
Objective To investigate the CT features of primary hepatic neuroendocrine carcinoma (PHNEC). Methods The findings 8 patients with PHNEC which was confirmed by surgery and histopathology were analyzed retrospectively. Tumor location, size, shape, margin, density, enhancement patterns degree, portal vein tumor thrombus, hilar retroperitoneal lymph node enlargement studied retrospectively. Results Of patients, there 5 tumors located in right liver, 1 left remaining 2 both livers....
Platinum-based chemo-resistance is the major issue for treatment of small cell lung cancer (SCLC). The integrative analysis multi-omics data a reliable approach discovering novel biomarkers associated with chemo-resistance. Here, and Cox regression found that higher expression PCDHB4 was poorer survival SCLC patients who received chemotherapy. gene hypomethylated upregulated in SCLC, which validated levels promoter methylation, mRNA, protein expression. Mechanistically, using bulk RNA-seq...