A5011131336- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Cardiovascular Function and Risk Factors
- Reliability and Agreement in Measurement
- Cardiomyopathy and Myosin Studies
- Heart Failure Treatment and Management
- Radiology practices and education
- Infective Endocarditis Diagnosis and Management
- Neurological and metabolic disorders
- Cardiovascular Effects of Exercise
- Galectins and Cancer Biology
- Long-Term Effects of COVID-19
- Gastroesophageal reflux and treatments
- Diversity and Career in Medicine
- Acute Ischemic Stroke Management
- Sleep and related disorders
- Cardiac Arrest and Resuscitation
- Infectious Encephalopathies and Encephalitis
Ben-Gurion University of the Negev
2016-2023
Soroka Medical Center
2020-2023
University Medical Center
2023
Lankenau Institute for Medical Research
2023
Women are underrepresented and thus sleep conditions underdiagnosed at clinics that evaluate sleep-disordered breathing. The most common sign of obstructive apnea (OSA) is snoring; therefore, it one the main red flags for suspected OSA. aim this study to determine whether self-reported snoring intensity by women men correlates with volume measured objectively during laboratory study.Consecutive patients who were referred a polysomnography (PSG) in university hospital over 2-year period had...
Abstract The 80% mortality rate of pancreatic-cancer (PC) makes early diagnosis a challenge. Oral fluids (OF) may be considered the ultimate body fluid for non-invasive examinations. We have developed techniques to improve visualization minor OF proteins thereby overcoming major barriers using as diagnostic fluid. aim this study was establish short discriminative panel biomarkers detection PC. Unstimulated were collected from PC patients and controls (n = 30). High-abundance-proteins...
Snoring and excessive daytime sleepiness (EDS) are major obstructive sleep apnea (OSA) symptoms. Snorers with apnea/hypopnea index < 5 designated "simple snorers" do not meet OSA criteria. This study aimed to explore a possible association between snoring intensity EDS defined as Epworth Sleepiness Scale (ESS) scores ≥ 11 in non-OSA subjects.Prospective cohort study.From total of 2,225 subjects who underwent polysomnography (PSG), 307 simple snorers qualified for the were assessed ESS score....
Abstract Background Cardiac troponin is the biomarker of choice for detection myocardial injury. There a great need simple point care testing among patients with chest pain, mainly in prehospital setting. In this preliminary study we evaluate feasibility novel, saliva-based cTn test. Aim 1) To presence cTnI saliva 2) explore point-of-care assay. Methods Saliva samples were collected from 32 injury who tested positive conventional cTnT blood tests, and 13 healthy volunteers. 25 9 these...
Herpes simplex virus (HSV) encephalitis is a known cause of cognitive deterioration, neurological disturbances, and seizures though are rarely associated with sinus node dysfunction.We present 54-year-old man admitted to the hospital 10-day history fever, confusion, fatigue, 1 week following transient loss consciousness. An initial workup suggested HSV patient was started on intravenous Acyclovir. Due his episode syncope, 24 h Holter electrocardiogram monitoring performed. The documented...
We discuss an unusual case of a patient who initially presented with apparent commotio cordis but returned several months later spontaneous wide complex tachycardia. This highlights the importance investigation survivors cordis, especially if atypical, to determine there is underlying cardiac disease. (Level Difficulty: Beginner.)
Cardiac troponin (cTn) is the biomarker of choice for detection myocardial injury. There a great need simple point-of-care (POC) testing among patients with chest pain, mainly in prehospital setting. The purpose this study was to evaluate presence cardiac I (cTnI) saliva injury using alpha-amylase depletion technique.Saliva samples were collected from 40 who tested positive conventional high-sensitivity T (cTnT) blood tests, and 66 healthy volunteers. Saliva treated removal salivary...
Introduction: Cardiac deletion of Bridging Integrator 1 (BIN1) membrane protein produces an age-related cardiomyopathy in mice. Our hypothesis was to determine whether electrical accompanies this structural remodeling and examine the utility VK-II-86, a analog carvedilol with minimum β-blocking activity, as potential antiarrhythmic therapeutic strategy. Methods: A cardiac-specific transgenic BIN1 KO mouse employed. Structural cardiac changes were assessed using echocardiography EKG (Visual...
Abstract Funding Acknowledgements Pfizer pharmaceutical corporation Background Diabetes is a known risk factor for thromboembolic events in patients with non-valvular atrial fibrillation (NVAF). Whether on insulin therapy are at an increased stroke compered to treated solely by oral antidiabetic medications not yet established. Aim To assess the of ischemic and mortality NVAF diabetes mellitus (DM) vs. treatment. Methods A prospective, historical cohort study based Clalit Health Services...
Abstract Funding Acknowledgements pfizer Background Diabetes mellitus (DM) is associated with increased risk of embolic complications in non-valvular atrial fibrillation (NVAF). Chronic kidney disease (CKD) has been shown some studies to increase the stroke. This finding not consistent among all studies. Therefore relationship between function, diabetes and stroke complex warrants further investigation. Purpose To assess incidence rates ischemic mortality by baseline Estimated Glomerular...
A 57-year-old woman presented to the emergency department with chest pain for several hours.Her past medical history consisted of dyslipidaemia, smoking, and recurrent events palpitations one previous event syncope.
Abstract Introduction: Secondary prevention of cardiovascular events among patients with diagnosed disease and high ischemic risk poses a significant challenge in clinical practice. The combinations aspirin low dose (LD) Ticagrelor or LD-Rivaroxaban have shown superiority preventing major adverse (MACE) than treatment alone. comparative value for money these two regimens remains unexplored. Methods : We analyzed each regimen's annual cost needed to treat (CNT) by multiplying the annualized...
A 13-year-old boy was hospitalized after a syncopal episode that occurred during exercise. He suddenly felt chest tightness, sweating and palpitations, followed by transient loss of conciseness. Upon emergency medical team arrival, he awake oriented. Baseline ECG showed sinus rhythm at rate 98 bpm, with narrow QRS, no signs long QT, Brugada, or pre-excitation. Physical examination, blood tests, 24 hours Holter monitoring, transthoracic echocardiography stress test were all within normal...
Introduction: Heart failure with preserved ejection fraction (HFpEF) is associated frequent hospitalizations and an increased risk of death. There are no therapies certain benefits for the treatment HFpEF. Spironolactone Sacubitril/Valsartan have shown marginal significance in HFpEF approved to treat this condition. We aimed compare value money these treatments. Hypothesis: provides better than preventing HF events patients Methods: compared cost needed (CNT) prevent composite outcome...
Introduction: Secondary prevention of cardiovascular events among patients with diagnosed disease and high ischemic risk poses a significant challenge in clinical practice. Both Ticagrelor low-dose (LD) Rivaroxaban have shown superiority preventing major adverse (MACE) than aspirin treatment alone. The comparative value for money these two regimens remains unexplored. Hypothesis: LD-Rivaroxaban are comparable their efficacy cost-effectiveness. Methods: We analyzed the annualized cost needed...