A5101650067- Lubricants and Their Additives
- Cancer-related molecular mechanisms research
- Tribology and Lubrication Engineering
- Advanced Sensor Technologies Research
- SARS-CoV-2 and COVID-19 Research
- Renal and related cancers
- T-cell and B-cell Immunology
- Advanced Thermoelectric Materials and Devices
- Adhesion, Friction, and Surface Interactions
- Diamond and Carbon-based Materials Research
- Microbial Metabolism and Applications
- Inflammasome and immune disorders
- RNA Research and Splicing
- Epigenetics and DNA Methylation
- Catalytic Processes in Materials Science
- Metal and Thin Film Mechanics
- Cancer Genomics and Diagnostics
- Calibration and Measurement Techniques
- Reproductive biology and impacts on aquatic species
- Chronic Kidney Disease and Diabetes
- Pharmacological Effects of Natural Compounds
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Scientific Measurement and Uncertainty Evaluation
- Circular RNAs in diseases
- COVID-19 Clinical Research Studies
Dalian Ocean University
2021-2025
Guizhou University
2024-2025
Hebei Medical University
2024
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Shandong University
2023-2024
Tianjin Municipal Research Institute for Family Planning
2024
Tianjin University of Technology
2024
Beijing Information Science & Technology University
2022-2024
Aero Engine Corporation of China (China)
2022-2024
Given the chronic inflammatory nature of Parkinson's disease (PD), T cell immunity may be important for onset. Here, we performed single-cell transcriptome and TCR sequencing, conducted integrative analyses to decode composition, function lineage relationship cells in blood cerebrospinal fluid PD. Combined expression TCR-based tracking, discovered a large population CD8+ showing continuous progression from central memory terminal effector PD patients. Additionally, identified group cytotoxic...
Rice (Oryza sativa) provides a staple food source for more than half the world population. However, current pace of rice breeding in yield growth is insufficient to meet demand ever-increasing global Genomic selection (GS) holds great potential accelerate progress and cost-effective via early before phenotypes are measured. Previous simulation experimental studies have demonstrated usefulness GS breeding. several affecting factors limitations require careful consideration when performing GS....
The world is facing a pandemic of Corona Virus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Adaptive immune responses are essential for SARS-CoV-2 virus clearance. Although large body studies have been conducted to investigate the mechanism in COVID-19 patients, we still lack comprehensive understanding BCR repertoire patients. In this study, used single-cell V(D)J sequencing characterize across convalescent We observed that diversity was...
Palmitic acid (PA) in root exudates or decaying residues can reduce the incidence of soil-borne diseases and promote growth some crop plants. However, effects PA on pathogens microbial communities are poorly understood. Here, we investigate overall watermelon populations Fusarium oxysporum f.sp. niveum (Fon). The mycelial spore production Fon were tested vitro, while its Fon, total bacteria fungi populations, evaluated a pot experiment. results revealed that all test concentrations inhibited...
Exposure to PM2.5 can cause serious harm the respiratory system. Until now, although many toxicological studies have shown that pulmonary fibrosis be caused by long-term exposure, there is no evidence Endothelial-Mesenchymal Transition (EndMT) trigger process of after exposure. LncRNAs are a class non-coding RNAs detected in mammalian cells. Nevertheless, researchers not found whether lncRNAs participate induced EndMT during pathophysiological duration. The Balb/c mouse model was exposed for...
As an important aquaculture fish, the genus Carassius exhibits different ploidy, including tetraploids and hexaploids [...].
Phytophthora root rot is a devastating disease of soybean caused by sojae. However, the resistance mechanism not yet clear. Our previous studies have shown that GmAP2 enhances sensitivity to P. sojae in soybean, and GmMYB78 downregulated transcriptome analysis GmAP2-overexpressing transgenic hairy roots. Here, was significantly induced susceptible overexpressing enhanced pathogen, while silencing sojae, indicating negative regulator Moreover, jasmonic acid (JA) content JA synthesis gene...
Cancer stemness is associated with metastases in kidney renal clear cell carcinoma (KIRC) and negatively correlates immune infiltrates. Recent evaluation methods based on the absolute expression have been proposed to reveal relationship between cancer. However, we found that existing do not perform well assessing of KIRC patients, they overlooked impact alternative splicing. Alternative splicing only progresses during differentiation stem cells, but also changes acquisition features cancer...
Cervical cancer is the third most common in women. Radiotherapy resistance remains a major obstacle for patients with cervical cancer. Somatic alterations human genomes are responsible radiotherapy resistance. Here, we performed single cell whole genome sequencing on 13 cells before and 12 after from Chinese woman patient carcinoma. We identified one damaging mutation NFKB1 (G430E), which showed significantly increased mutant allele frequency than that radiotherapy. Further functional assays...
Indium tin oxide (ITO) thin films suffer from poor chemical stability at high temperatures because of the instability point defects and structural variations. An interface design strategy was proposed herein to improve this situation, where a robust ITO-based film with column-layer structure fabricated. Three types ITO were fabricated via magnetron sputtering. By tuning interfaces, we controlled effective mass weighted mobility, enhancing electrical conductivity (2.17 × 106 S m-1) power...
Abstract Background Immunotherapy is a practical therapeutic approach in breast cancer (BRCA), and the role of FLI1 immune regulation has gradually been unveiled. However, specific BRCA was conflicted; thus, additional convincing evidence needed. Methods We explored upstream expression via summary data-based Mendelian randomization (SMR) analysis ncRNA network construction centering on using genome-wide association study (GWAS) data with quantitative trait loci (eQTLs) DNA methylation...
ABSTRACT In order to investigate the impact of micro‐textured surfaces with varying surface density on coating properties, bionic leaf vein micro‐texture different densities were prepared substrate by laser processing. Bi 2 S 3 soft coatings deposited textured electrohydrodynamic atomization. The influence adhesion and tribological properties was analysed discussed scratch tests friction wear tests. results showed a significant increase in coefficient as increased. However, after reaching...
PM 2 . 5 refers to atmospheric particulate matters with a diameter of less than 2.5 μm. The deposit in lung cells can cause oxidative stress, leading changes macrophage polarity, which subsequently pulmonary inflammation. Long-chain non-coding RNA (lncRNA) is class transcripts that regulate biological processes through multiple mechanisms. However, the role lncRNA -induced inflammation has not been established. In this study, effects and associated mechanism change polarity were...