A5064772233- Cardiac Arrest and Resuscitation
- EEG and Brain-Computer Interfaces
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Epilepsy research and treatment
- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Organ Donation and Transplantation
- Autoimmune Neurological Disorders and Treatments
- Intensive Care Unit Cognitive Disorders
- Grief, Bereavement, and Mental Health
- Acute Ischemic Stroke Management
- Functional Brain Connectivity Studies
- Neonatal and fetal brain pathology
- Neurological Disease Mechanisms and Treatments
- Cerebrospinal fluid and hydrocephalus
- Infectious Encephalopathies and Encephalitis
- Cerebrovascular and Carotid Artery Diseases
- Diet and metabolism studies
- Genetics and Neurodevelopmental Disorders
- Pharmacological Effects and Toxicity Studies
- Peripheral Neuropathies and Disorders
- Microbial Metabolism and Applications
- Stroke Rehabilitation and Recovery
- Electrolyte and hormonal disorders
Capital Medical University
2016-2025
Guizhou University
2025
Chongqing Normal University
2024
Beijing Tongren Hospital
2024
Peking University
2015-2024
National Health and Family Planning Commission
2022-2024
National Clinical Research Center for Digestive Diseases
2023-2024
China-Japan Friendship Hospital
2023
Tianjin Medical University General Hospital
2018
Shanghai Xuhui Central Hospital
2018
<h3>Importance</h3> There are inconsistencies in concept, criteria, practice, and documentation of brain death/death by neurologic criteria (BD/DNC) both internationally within countries. <h3>Objective</h3> To formulate a consensus statement recommendations on determination BD/DNC based review the literature expert opinion large multidisciplinary, international panel. <h3>Process</h3> Relevant professional societies were recruited to develop regarding BD/DNC. Literature searches Cochrane,...
We aimed to evaluate the efficacy of remote ischemic conditioning (RIC) in patients with cerebral small-vessel disease.Thirty disease-related mild cognitive impairment were enrolled this prospective, randomized controlled study for 1 year. Besides routine medical treatment, participants into experimental group (n=14) undergoing 5 cycles consisting ischemia followed by reperfusion minutes on both upper limbs twice daily year or control (n=16) who treated sham ischemia-reperfusion cycles. The...
Background and Purpose— We conducted this randomized controlled trial to investigate the effects of therapeutic hypothermia on mortality neurological outcome in patients with massive cerebral hemispheric infarction. Methods— Patients within 48 hours symptom onset were either a group or control group. given standard medical treatment plus endovascular target temperature 33 34°C. Hypothermia was maintained for minimum 24 hours. only normothermia. The primary end points modified Rankin Scale...
Background and aims To investigate the feasibility, safety effectiveness of ketogenic diet (KD) for super-refractory status epilepticus (SRSE) in intensive care unit (ICU). Methods We conducted a prospective investigation on patients with SRSE treated KD. The primary outcome measures were ketosis development as biomarker feasibility resolution effectiveness. KD-related side effects also investigated. Results Twelve (9 females 3 males) SRSE, median age 34 years [range 16–69, interquartile...
<title>Abstract</title> The full text of this preprint has been withdrawn by the authors due to necessary revisions in study endpoints and methodology ensure alignment with current clinical research standards. Therefore, do not wish work be cited as a reference. Questions should directed corresponding author.
Abstract SMARCA2 and SMARCA4 are essential, redundant, catalytic subunits of the multi-subunit BRG1/BRM-associated factor (BAF) complex. This complex regulates gene expression DNA repair through chromatin remodeling activity. The paralogues bind acetylated histones their highly conserved bromodomains alter DNA-histone contacts using ATP-dependent helicase Recently, mutations in specific components BAF have been identified. Of great interest loss function SMARCA4, found 5-7% all human cancers...
Abstract Background Hypoalbuminemia, often induced by acute stress and inflammation in patients who are neurocritically ill, is adversely associated with prognosis. This study investigates whether supplementing nutrition support anti‐inflammatory whey protein powder formulations (experimental group) can improve serum albumin levels overall patient outcomes compared traditional liquid intact (control while monitoring for enteral feeding complications inflammatory markers. Methods In a...
Objective. To test the value of quantifiable electrical stimuli as a reliable method to assess electroencephalogram reactivity (EEG-R) for early prognostication outcome in comatose patients. Methods. EEG was recorded consecutive adults coma after cardiopulmonary resuscitation (CPR) or stroke. EEG-R standard tested. Each patient received 3-month follow-up by Glasgow-Pittsburgh cerebral performance categories (CPC) modified Rankin scale (mRS) score. Results. Twenty-two patients met inclusion...
Few studies have investigated affective flexibility in individuals with high autistic traits. In the present study, we employed an adapted task-switching paradigm combined event related potential (ERP) technology to explore Participants were instructed switch between identifying gender (gender task) and emotion (emotion of presented faces. Two groups participants recruited based on their scores Autism Spectrum Quotient (AQ): a High Autistic Group (HAG) Low (LAG). The results confirmed that...
<b><i>Objective:</i></b> This study aimed to control blood pressure (BP) under transcranial Doppler (TCD) guidance in patients with anterior circulation acute ischemic stroke after endovascular treatment (EVT) reduce the incidence of early neurological deterioration (END) and improve prognosis. <b><i>Methods:</i></b> prospective randomized controlled included 95 who were randomly divided into a TCD-guided BP (TBC) group non-TCD-guided (NBC)...
To evaluate the cognitive and neurofunctional outcomes in patients with anti-leucine-rich glioma inactivated 1 (LGI1) encephalitis.A cohort follow-up study was performed after a median of 33 months (range 6-78) from disease onset to last diagnosed anti-LGI1 encephalitis, assess using modified Rankin Scale (mRS), activities daily living (ADL), neuropsychiatric inventory (NPI) telephone interview for status (TICS-M). Remote symptomatic seizure clinical relapses were also recorded. The...
INTRODUCTION Currently, the recommended therapy to control refractory status epilepticus (RSE) is intravenous (IV) anesthetics, such as midazolam, propofol, barbiturates, and so on. However, 15%–26% of RSE cases still cannot be terminated. Three case series studies have demonstrated that combination IV anesthetics moderate (30–31°C) or mild (31–35°C) hypothermia successfully terminated seizures in patients.[12] But high rebound rate after rewarming, mortality during hospitalization severe...
The intensive care of critically ill patients with large hemispheric infarction improves the survival rate. However, established prognostic markers for neurological outcome show variable accuracy. We aimed to assess value electrical stimulation and quantitative analysis EEG reactivity early prognostication in this population.We prospectively enrolled consecutive between January 2018 December 2021. was randomly performed by pain or via visual analysis. Neurological within 6-month dichotomized...