A5013137905- Mosquito-borne diseases and control
- Tuberculosis Research and Epidemiology
- Global Maternal and Child Health
- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- Viral Infections and Vectors
- HIV/AIDS drug development and treatment
- Virology and Viral Diseases
- Child Nutrition and Water Access
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 epidemiological studies
- HIV Research and Treatment
- Parasites and Host Interactions
- Hepatitis B Virus Studies
- Maternal and Neonatal Healthcare
- Syphilis Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Zoonotic diseases and public health
- Leprosy Research and Treatment
- Data-Driven Disease Surveillance
- Parasitic Diseases Research and Treatment
- Pneumonia and Respiratory Infections
- Vaccine Coverage and Hesitancy
- Diagnosis and treatment of tuberculosis
- Viral gastroenteritis research and epidemiology
Universidade de Pernambuco
2016-2025
Universidade Federal de Pernambuco
2016-2025
University Gama Filho
2025
Universidade de Brasília
2025
Universidade Federal de São Paulo
2012-2022
Hospital das Clínicas da Universidade Federal de Pernambuco
2009-2021
Hospital Universitário Oswaldo Cruz
2003-2020
London School of Hygiene & Tropical Medicine
2020
Faculdade de Ciências Médicas de Minas Gerais
2017
Fundação Oswaldo Cruz
2016-2017
To provide an initial description of the congenital syndrome presumably associated with infection by Zika virus compared other syndromes including infections established etiologies.We overview a published case series 35 cases, clinical 104 and unpublished reports laboratory findings describing cases diagnosed since beginning epidemic microcephaly in Brazil.About 60% to 70% mothers report rash during pregnancy; mainly first trimester. Principal features are microcephaly, facial...
Starting in August 2015, there was an increase the number of cases neonatal microcephaly Northeast Brazil. These findings were identified as being epidemic related to Zika virus (ZIKV) infection. The present study aims analyse spatial distribution Recife (2015–2016), which is Brazil, and its association with living conditions this city. This ecological that used data from reported State Health Department Pernambuco (August 2015 July 2016). basic unit analysis 94 districts Recife. case...
To determine the sociodemographic, behavioral, and health care factors related to occurrence of syphilis in women treated at public maternity hospitals.This is a case-control study (239 cases 322 controls) with admitted seven hospitals municipality Recife, Brazil, from July 2013 2014. Eligible were recruited after result VDRL (Venereal Disease Research Laboratory) under any titration. The selection controls was based on serology for using ELISA (enzyme-linked immunosorbent assay)....
Resumo No Brasil, a pandemia da COVID-19 tem sido severa nos estados das regiões mais pobres, como o Nordeste. A falta de políticas nacionais para controle levou as autoridades estaduais e municipais implementarem medidas saúde pública. O objetivo deste estudo é mostrar efeito dessas na epidemia. maior incidência entre os nove do Nordeste foi registrada em Sergipe, Paraíba Ceará. Piauí, Ceará foram que testaram. Muitos apresentavam alta proporção pessoas trabalho informal. Estados com...
A cohort of cases initiating tuberculosis treatment from May 2001 to July 2003 was followed in Recife, Pernambuco State, Brazil, investigate biological, clinical, social, lifestyle, and healthcare access factors associated with three negative outcomes (treatment failure, dropout, death) separately as a group. Treatment failure delay, illiteracy, alcohol consumption. Factors dropout were age, prior TB treatment, illiteracy. Death HIV co-infection, head family's income. Main whole alcoholism,...
Resumo Mesmo no período em que a pandemia de Covid-19 encontrava-se crescimento Nordeste do Brasil, iniciou-se adoção medidas flexibilização distanciamento social. O objetivo estudo é o avaliar pertinência das propostas flexibilização, tomando-se conta situação da cada local e momento foram adotadas. Tendo como referência as diretrizes OMS, construídos analisados indicadores operacionais para diretriz, contexto região Nordeste. Para análise comportamento epidemia, conforme selecionados,...
Knowledge regarding the risks associated with Zika virus (ZIKV) infections in pregnancy has relied on individual studies relatively small sample sizes and variable risk estimates of adverse outcomes, or surveillance routinely collected data. Using data from Brazilian Cohorts Consortium, this study aims, to estimate outcomes among offspring women RT-PCR-confirmed ZIKV infection during explore heterogeneity between studies.We performed an participant meta-analysis 1548 pregnant 13 studies,...
Abstract Objective To evaluate the effect of intrathecal therapy with human antitetanus immunoglobulin on clinical progression and mortality from tetanus. Design Randomised controlled trial. Setting Intensive care unit a university hospital, Pernambuco, Brazil. Participants 120 patients tetanus allocated to by either intramuscular route (n = 58) or 62; control group). Main outcome measures Clinical disease, duration hospital stay, occurrence spasms, complications, respiratory infection,...
Background Recent tobacco smoking has been identified as a risk factor for developing tuberculosis, and two studies which have investigated its association with relapse of tuberculosis after completion treatment had conflicting results (and did not control confounding). The objective this study was to investigate factors relapse, emphasis on smoking. Methods A cohort newly diagnosed TB cases followed up from their discharge (in 2001–2003) until October 2006 relapses ascertained during that...
Background Tuberculosis is known to have socio-economic determinants at individual and area levels, but it not whether they are independent, interact their relative contributions the burden of tuberculosis. Methods A case–control study was conducted in Recife, Brazil, investigate social tuberculosis, explore relationship between two levels calculate contribution It included 1452 cases tuberculosis diagnosed by services 5808 controls selected random from questionnaires completed for...
The main objective of this study was to investigate the risk factors associated with periodontitis in pregnant women.This conducted two stages. In Stage 1, a cross-sectional determine prevalence among 810 women treated at maternity ward university hospital. 2, were investigated groups women: 90 and 720 without. A hierarchized approach evaluation used analysis, independent variables related grouped into levels: 1) socio-demographic variables; 2a) nutritional status, smoking, number...
Background The measurement of CD4+ T-cell (CD4) counts is a strong predictor progression to AIDS and means monitoring antiviral therapy (ART). success or failure controlling virus levels in untreated patients those taking ART may be associated with treatment adherence, habits, correlated infections unrelated HIV, cancer, immunosuppressive drugs; as well socio-economic psychosocial aspects access healthcare. aim the present study was identify, using multilevel model, factors related...
The aim of this study was to identify factors associated with geographic access health services by tuberculosis patients in three State capitals Northeast Brazil. sample consisted new cases reported 2007. used data from the Information System on Notifiable Diseases and National Registry Healthcare Organizations. Addresses households were geocoded, difficult defined as a distance greater than 800 meters household service. Crude prevalence ratios estimated, well adjusted using Poisson...
In August 2015, pediatric neurologists at public hospitals in Recife, Pernambuco State, Brazil, observed an increase the number of disproportional microcephaly cases associated with other congenital anomalies. The fact caused social commotion and mobilization academic community led Brazilian Ministry Health to declare a national health emergency, followed by declaration Public Emergency International Concern World Organization. hypothesis for phenomenon was Zika virus (ZIKV) infection, based...
BACKGROUND Schistosomiasis mansoni is a poverty-related parasitic infection that has variety of clinical manifestations. We consider the disability and deaths caused by schistosomiasis unacceptable for tool-ready disease. Its condition in Brazil warrants an analysis will enable better understanding local health losses contribute to complex decision-making process. OBJECTIVE This study estimates cost 2015. METHODS conducted illness 2015 based on prevalence approach from societal perspective....
Defining cases of Zika virus (ZIKV) infection is a critical challenge for epidemiological research. Due to ZIKV’s overlapping clinical features and potential immunologic cross-reactivity with other flaviviruses the current lack an optimal ZIKV-specific diagnostic assay, varying approaches identifying ZIKV infections have been employed date. This paper presents laboratory results criteria developed by Microcephaly Epidemic Research Group defining maternal in cohort pregnant women rash (N =...
Background The objectives were to estimate the prevalence of hepatitis A among children and adolescents from Northeast Midwest regions Federal District Brazil identify individual-, household- area-levels factors associated with infection. Methods This population-based survey was conducted in 2004–2005 covered individuals aged between 5 19 years. stratified multistage cluster sampling technique probability proportional size used select 1937 years living capital State capitals 12 states study...
A cross-sectional study was conducted using body mass index (BMI) to estimate the prevalence of thinness and overweight/obesity associated factors in 2,018 individuals with HIV/AIDS attending health services referral centers. The dependent variable classified as thinness, eutrophy. Multinomial logistic regression analyses were performed considering eutrophy reference level. 8.8% overweight/obesity, 32.1%. variables anemia CD4 cell count < 200mm³. risk age > 40 years diabetes, identified...
Background This study aimed to identify the transmission pattern of hepatitis A (HA) infection based on a primary dataset from Brazilian National Hepatitis Survey in pre-vaccination context. The national survey conducted urban areas disclosed two epidemiological scenarios with low and intermediate HA endemicity. Methods catalytic model was built seroprevalence (2005 2009). data 7,062 individuals aged 5–69 years all macro-regions were included. We up three models: fully homogeneous mixing...