A5054054935- Advanced Surface Polishing Techniques
- Advanced machining processes and optimization
- Advanced Machining and Optimization Techniques
- Advanced Measurement and Metrology Techniques
- Laser Material Processing Techniques
- Diamond and Carbon-based Materials Research
- Plant Pathogens and Fungal Diseases
- Engineering Applied Research
- Enzyme Structure and Function
- Metal and Thin Film Mechanics
- Surface Roughness and Optical Measurements
- Advanced optical system design
- Mycotoxins in Agriculture and Food
- RNA and protein synthesis mechanisms
- Fungal Plant Pathogen Control
- Tunneling and Rock Mechanics
- Laser and Thermal Forming Techniques
- Robot Manipulation and Learning
- Advanced Sensor and Energy Harvesting Materials
- Protein Structure and Dynamics
- Tactile and Sensory Interactions
- Genomics and Phylogenetic Studies
- Adhesion, Friction, and Surface Interactions
- Gastric Cancer Management and Outcomes
- Plant Disease Resistance and Genetics
Mie Agricultural Research Institute
2012-2024
Chubu University
2014-2024
Kyoto University
2024
Fujitsu (China)
2022-2023
Shibaura Institute of Technology
2023
Waseda University
2019-2022
Kagawa University
2022
Musashino University
2018-2021
Fujita Animal Hospital
2021
Chibaken Saiseikai Narashino Hospital
2005-2020
The Protein Data Bank (PDB) is the single global archive of experimentally determined three-dimensional (3D) structure data biological macromolecules. Since 2003, PDB has been managed by Worldwide (wwPDB; wwpdb.org), an international consortium that collaboratively oversees deposition, validation, biocuration, and open access dissemination 3D macromolecular data. Core Archive houses atomic coordinates more than 144 000 structural models proteins, DNA/RNA, their complexes with metals small...
The Protein Data Bank Japan (PDBj, http://pdbj.org), a member of the worldwide (wwPDB), accepts and processes deposited data experimentally determined macromolecular structures. While maintaining archive in collaboration with other wwPDB partners, PDBj also provides wide range services tools for analyzing structures functions proteins. We herein outline updated web user interfaces together RESTful backend relational database that support former. To enhance interoperability PDB data, we have...
Diabetes affects cardiac structure and function, it has been suggested that diabetes leads to cardiomyopathy. Arachidonate 12/15-lipoxygenase (LOX) play an important role in atherogenesis heart failure. However, the of 12/15-LOX diabetic cardiomyopathy not examined. In this study, we investigated effects on We created streptozotocin (STZ)-induced mice compared them with Alox15-deficient mice. Expression inflammatory cytokines such as tumor necrosis factor (TNF)-α nuclear (NF)-κB were...
The Protein Data Bank Japan (PDBj), a member of the worldwide (wwPDB), accepts and processes deposited data experimentally determined biological macromolecular structures. In addition to archiving PDB in collaboration with other wwPDB partners, PDBj also provides wide range original unique services tools, which are continuously improved updated. Here, we report new RDB Mine 2, WebGL molecular viewer Molmil, ProMode-Elastic server for normal mode analysis, virtual reality system eF-site...
KaiA, KaiB and KaiC are cyanobacterial circadian clock proteins. contains two ATP/GTP-binding Walker's motif As, mutations in these regions affect the oscillations.ATP induced hexamerization of KaiC. The Km value for ATP was 1.9 micro m. Triphosphate nucleotides bound to their binding functioned cooperatively hexamerization. An unhydrolysable substrate, 5'-adenylylimidodiphosphate (AMPPNP), also hexamerization, indicating that nucleotide binding, but not its hydrolysis, is essential...
Ring-shaped sliding clamps and clamp loader ATPases are essential factors for rapid accurate DNA replication. The ring is opened resealed at the primer–template junctions by ATP-fueled function. processivity of polymerase conferred its attachment to loaded onto DNA. In eukarya archaea, replication factor C (RFC) proliferating cell nuclear antigen (PCNA) play crucial roles as clamp, respectively. Here, we report electron microscopic structure an archaeal RFC–PCNA–DNA complex 12-Å resolution....
Protein Data Bank Japan (PDBj), a founding member of the worldwide (wwPDB) has accepted, processed and distributed experimentally determined biological macromolecular structures for 20 years. During that time, we have continuously made major improvements to our query search interface PDBj Mine 2, BMRBj web interface, EM Navigator PDB/BMRB/EMDB entries. also serves PDB-related secondary database data, original web-based modeling services such as Homology complex structure (HOMCOS),...
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), has been used for structure characterization of 1-aminopyrene-3,6,8-trisulfonate (APTS)-derivatized oligosaccharides previously separated by capillary electrophoresis (CE). The resolved components were first isolated employing an automated high-resolution fraction collector. Using on-probe sample cleanup with a cation-exchange resin and matrix mixture (1:1) 6-hydroxypicolinic acid 3-hydroxypicolinic...
Abstract Background It is presently unclear whether glycemic variability (GV) associated with baroreflex sensitivity (BRS), which an early indicator of cardiovascular autonomic neuropathy. The present study the first to examine relationships between BRS and GV measured using continuous glucose monitoring (CGM). Methods This was a multicenter, prospective, open-label clinical trial. A total 102 patients type 2 diabetes were consecutively recruited for this study. assessed by measuring...
Abstract Summary: Omokage search is a service to the global shape similarity of biological macromolecules and their assemblies, in both Protein Data Bank (PDB) Electron Microscopy (EMDB). The server compares shapes assemblies independent sequence order number subunits. As query, user inputs structure ID (PDB or EMDB ID) uploads an atomic model 3D density map server. performed usually within 1 min, using one-dimensional profiles (incremental distance rank profiles) characterize shapes. Using...