A5007832335- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Cancer Risks and Factors
- Advanced Radiotherapy Techniques
- Cancer Treatment and Pharmacology
- Lymphatic System and Diseases
- BRCA gene mutations in cancer
- Advances in Oncology and Radiotherapy
- Economic and Financial Impacts of Cancer
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Cancer and Skin Lesions
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Radiomics and Machine Learning in Medical Imaging
- Cutaneous Melanoma Detection and Management
- Cancer Genomics and Diagnostics
- Cancer survivorship and care
- Salivary Gland Tumors Diagnosis and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Advanced Breast Cancer Therapies
- Sarcoma Diagnosis and Treatment
- Virus-based gene therapy research
University of Miami
2018-2025
Sylvester Comprehensive Cancer Center
2018-2025
Miami University
2025
University of Miami Health System
2024
University of Miami Hospital
2021-2024
Cancer Institute (WIA)
2021
Molecular Oncology (United States)
2021
University of Maryland, Baltimore
2009-2017
University of Maryland, College Park
2017
University of Maryland Baltimore Washington Medical Center
2016
Natural killer (NK) cells are cytotoxic lymphocytes that accumulate within the tumor microenvironment and generally considered to be antitumorigenic. Using single-cell RNA sequencing functional analysis of multiple triple-negative breast cancer (TNBC) basal samples, we observed a unique subcluster Socs3 high CD11b − CD27 immature NK were present only in TNBC samples. These tumor-infiltrating expressed reduced granzyme signature and, mice, responsible for activating stem through Wnt...
Purpose Although bevacizumab (BV) increases survival rates when used with chemotherapy (CTX) in patients who have metastatic colorectal cancer (CRC), an increase wound complications has been observed undergo surgery while receiving BV. We therefore evaluated whether neoadjuvant BV is associated postoperative undergoing for CRC liver metastases. Patients and Methods Two subgroups of received CTX + (n = 81) or alone 44) were identified from a database underwent Univariate multivariate logistic...
Objective: To analyze the effect of economic and racial/ethnic residential segregation on breast cancer-specific survival (BCSS) in South Florida, a diverse metropolitan area that mirrors projected demographics many United States regions. Summary Background Data: Despite advances diagnosis treatment, racial disparities BCSS. This study evaluates these through lens segregation, which approximate impact structural racism. Methods: Retrospective cohort stage I to IV cancer patients treated at...
Importance Neighborhood-level disadvantage is an important factor in the creation and persistence of underresourced neighborhoods with undue burden disparate breast cancer–specific survival outcomes. Although studies have evaluated neighborhood-level after accounting for individual-level socioeconomic status (SES) large national cancer databases, these are limited by age, socioeconomic, racial ethnic diversity. Objective To investigate neighborhood SES (using a validated comprehensive...
Importance Unmet social needs in local populations may hinder the development of targeted cancer control interventions aimed at improving screening utilization and early-stage breast diagnosis to ultimately improve survival disparities. Objective To evaluate if (1) city-funded mammography is associated with mammography, (2) unmet are (3) later-stage disease diagnosis. Design, Setting, Participants This cohort study included patients stages I-IV invasive ductal or lobular carcinoma treated an...
Nearly 25% of opioid-related deaths are from prescribed opioids, and the exacerbation opioid epidemic by coronavirus disease 2019 (COVID-19) pandemic underscores urgent need to address superfluous prescribing. Therefore, we sought align local prescribing practices with national guidelines in postoperative non-metastatic breast cancer patients. A single-institution analysis included surgery patients treated between April 2020 July 2021. 'Overprescription' was defined as a discharge...
As the breast cancer survivor population increases, topic of screening these women for recurrences is increasingly relevant. In our institution, we use both MRI and mammography in surveillance survivors, although little data exists on this setting. We present a retrospective analysis experience compare sensitivity specificity vs.
Objective: To determine the association between objective (geospatial) and subjective (perceived) measures of neighborhood disadvantage (ND) aggressive breast cancer (BCa) tumor biology, defined using validated social adversity-associated transcription factor (TF) activity clinical outcomes. Summary Background Data: ND is associated with shorter BCa recurrence-free survival (RFS), independent individual, tumor, treatment characteristics, suggesting potential unaccounted biological mechanisms...
Abstract Background: In patients with micro- and macrometastases in the sentinel lymph node (SLN) after neoadjuvant chemotherapy (NAC), additional positive nodes are found >60% of cases axillary dissection (ALND) is currently considered standard care. The likelihood finding residual isolated tumor cells (ITCs) unknown, benefit ALND unclear. As a consequence, surgical management axilla these not standardized. We sought to evaluate how often found, determine factors associated ALND,...
The nodal burden of patients with residual isolated tumor cells (ITCs) in the sentinel lymph nodes (SLNs) after neoadjuvant chemotherapy (NAC) (ypN0i+) is unknown, and axillary management not standardized. We investigated rates additional positive (LNs) at node dissection (ALND) oncologic outcomes ypN0i+ treated without ALND.
To investigate the impact of global and local genetic ancestry neighborhood socioeconomic status (nSES), on breast cancer (BC) subtype, gene expression.Higher rates aggressive BC subtypes [triple negative (TNBC)] worse overall survival are seen in black women [Hispanic Black (HB) non-Hispanic (NHB)] from low nSES. However, complex relationship between ancestry, nSES, subtype etiology remains unknown.Genomic analysis was performed peripheral blood a cohort 308 stage I to IV White (NHW),...
To understand the impact of Black race on breast cancer (BC) presentation, treatment, and survival among Hispanics.It is well-documented that non-Hispanic Blacks (NHB) present with late-stage disease, are less likely to complete have worse compared their White (NHW) counterparts. However, no data evaluates whether this disparity extends Hispanic (HB) Whites (HW). Given our location in Miami, gateway Latin America Caribbean, we diversity evaluate BC outcomes HB HW.Retrospective cohort study...