- Membrane Separation Technologies
- Solar-Powered Water Purification Methods
- Solar Thermal and Photovoltaic Systems
- Asthma and respiratory diseases
- Stress Responses and Cortisol
- Inhalation and Respiratory Drug Delivery
- Parkinson's Disease Mechanisms and Treatments
- Immunotherapy and Immune Responses
- Nerve injury and regeneration
- Lanthanide and Transition Metal Complexes
- Immune Cell Function and Interaction
- Bladder and Urothelial Cancer Treatments
- Customer churn and segmentation
- Cryospheric studies and observations
- COVID-19 diagnosis using AI
- Plant Ecology and Soil Science
- Peptidase Inhibition and Analysis
- Tryptophan and brain disorders
- Electron Spin Resonance Studies
- Advanced MRI Techniques and Applications
- Sepsis Diagnosis and Treatment
- Arctic and Antarctic ice dynamics
- Hemodynamic Monitoring and Therapy
- Climate variability and models
- IL-33, ST2, and ILC Pathways
Guangzhou University
2017-2025
Tianjin University of Traditional Chinese Medicine
2018-2024
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2021-2024
Tianjin haihe hospital
2024
Wuhan Textile University
2023-2024
First Affiliated Hospital of Zhengzhou University
2022-2024
Second Affiliated Hospital of Zhejiang University
2022-2024
Zhengzhou University
2021-2023
Fudan University
2022-2023
State Council of the People's Republic of China
2022
Acute lung injury (ALI), a severe health-threatening disease, has risk of causing chronic pulmonary fibrosis. Informative and powerful evidence suggests that inflammation oxidative stress play central role in the pathogenesis ALI. Quercetin is well recognized for its excellent antioxidant anti-inflammatory properties, which showed great potential ALI treatment. However, application quercetin often hindered by low solubility bioavailability. Therefore, to overcome these challenges, an...
Brain-derived neurotrophic factor (BDNF) with neuronic development and function is a promising therapeutic agent for treating depressive disorder, according to the neurotrophin hypothesis. However, delivery of BDNF into brain not easy as these large protein molecules cannot efficiently cross blood-brain barrier (BBB) easily suffer oxidative damage in vivo. Therefore, quercetin-based alginate nanogels (quercetin nanogels) loaded have been developed, which could bypass BBB via nose-to-brain...
NK cells play important roles in anti‐tumor immunity. CD 226 is a major ‐cell activating receptor, which transduces signals after binding ligands 155 and 112. Here, we demonstrated that activated unfolded protein response ( UPR ) attenuated the sensitivity of human hepatocellular carcinoma cell HCC to cytotoxicity by decreasing expression level ligand . The decreased was due involvement transcription factor 6 ATF 6) inositol‐requiring enzyme 1α IRE 1α) pathways. In addition, pathway...
Parkinson's disease (PD) is a severe neurodegenerative with high incidence in the elderly and mainly treated by drugs. The blood–brain barrier (BBB) limits entry of oral neuroactive drugs to brain, reducing drug concentration affecting treatment PD. Nanotechnology-based delivery systems, especially thermosensitive allow access brain via nose-brain pathway, which not limited presence BBB. These systems demonstrate outstanding performance enhancing accumulation active drugs, improving loading...
Abstract Physical reservoir computing (PRC) holds great promise for low‐latency, energy‐efficient information processing, yet current implementations often suffer from limited flexibility, adaptability, and environmental stability. Here, a PRC system based on pulse‐width modulation (PWM)‐encoded resistor‐capacitor ( R – C ) circuits is introduced, achieving exceptional versatility robustness. By leveraging customizable nonlinearities dynamic timescales, this achieves state‐of‐the‐art...
Aims CD 155 is an important ligand in triggering tumour rejection by immune cells. However, the expression of and its clinical significance hepatocellular carcinoma ( HCC ) remains unknown. Methods results We examined level 174 tissue samples immunohistochemical staining cell lines flow cytometry; 63.8% (111 174) showed negative expression. When compared with adjacent peritumour tissues, tissues exhibited a significantly lower P < 0.001). Flow cytometry analysis indicated that had low...
Interfacial solar-driven desalination technology holds great promise for solving global freshwater scarcity. However, it is still a challenge to develop solar evaporator that can handle high concentration of brine with excellent evaporation rates. Herein, three-dimensional (3D) (FeTa-PFP) developed by coating polyester fiber pillar (PFP) ferric tannate (FeTa) using simple solution immersion method. Black FeTa improves the sunlight absorption PFP 93%. vertical water-transporting channels...
Background: The aim of the present study was to explore risk variants for coronary artery disease (CAD) and evaluate their joint effects (quantified by genetic score; GRS) on discrimination CAD in a Chinese Han sample. Methods Results: An association analysis 91 single nucleotide polymorphisms (SNPs) with undertaken 1,007 patients 889 healthy controls. Two GRSs, counted GRS (cGRS) weighted (wGRS), were calculated using significant SNPs, discriminant power assessed receiver-operating...
Abstract Background Carbapenem-resistant gram-negative bacteria (CRGNB) have become a public health concern worldwide. The risk factors associated with CRGNB infection after colonization are unknown, nor is the optimal timing of antibiotic treatment, warranting further investigation. Methods A 4-year single-center prospective observational study was conducted. CRGNB-colonized patients were incorporated on admission into our observation cohort for an active surveillance culture program, and...
Here is the first report on polyester-based nanocarriers fabricated via ring-opening polymerization-induced self-assembly (ROPISA) of salicylic acid o-carboxyanhydride (SAOCA). This ROPISA process affords well-defined diblock copolymers that interestingly form an original cylindrical morphology.
This study aimed to determine the effects of smoke bomb-induced acute inhalation injury on pulmonary function at different stages lung injury.We performed tests (PFTs) in 15 patients with from days 3 180 after inhalation. We measured trace element zinc whole blood 4 and 17, correlations levels PFTs were performed.In stage (day 3), 11 mild symptoms had normal 8 restrictive ventilatory dysfunction reduced diffusing capacity. Some also obstructive (5 patients) a decline small airway (6...