A5008922508- Criminal Law and Policy
- Law and Political Science
- Plant and animal studies
- Criminal Law and Evidence
- Insect and Arachnid Ecology and Behavior
- Medical and Health Sciences Research
- Digitalization, Law, and Regulation
- Insect and Pesticide Research
- Immune Cell Function and Interaction
- Physiological and biochemical adaptations
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gut microbiota and health
- Neurobiology and Insect Physiology Research
- Pancreatic and Hepatic Oncology Research
- Animal Behavior and Reproduction
- Cancer Immunotherapy and Biomarkers
- Liver Disease Diagnosis and Treatment
- Public Administration and Political Analysis
- Plant Parasitism and Resistance
- European Criminal Justice and Data Protection
- Medical Practices and Rehabilitation
- Ecology and Vegetation Dynamics Studies
- Immune cells in cancer
- Entomological Studies and Ecology
- Corporate Governance and Management
Medizinische Hochschule Hannover
2022-2025
University of Tübingen
2017-2024
Center for Cancer Research
2017-2023
National Institutes of Health
2017-2023
National Cancer Institute
2017-2023
Bernstein Center for Computational Neuroscience Tübingen
2022
Tbilisi State University
2021
European Faculty of Law
2021
Ghent University
2021
Government of the United States of America
2021
Primary liver tumors and metastasis currently represent the leading cause of cancer-related death. Commensal bacteria are important regulators antitumor immunity, although is exposed to gut bacteria, their role in surveillance poorly understood. We found that altering commensal mice induced a liver-selective effect, with an increase hepatic CXCR6+ natural killer T (NKT) cells heightened interferon-γ production upon antigen stimulation. In vivo functional studies showed NKT mediated tumor...
Bumblebees of any one species in Maine forage for pollen and/or nectar from a large variety morphologically diverse flowers, but individuals have limited foraging repertoires at time. Unspecialized were sometimes unsuccessful extracting highly rewarding flowers. In area with concurrently blooming plants, the bumblebees had apparent preferences. Superimposed on preferences individual Individuals primary specialties (their majors) and secondary specialities minors). Minors often bridges to new...
On their first 2 foraging trips out of the hive, young Bombus vagans workers visited, on average, 4 or 5 different kinds rewarding as well unrewarding flowers, and few each kind in succession. But, after 3—7 trips, most bees specialized jewelweed, which was numerous flower available with high nectar reward. When jewelweed specialists became numerous, food rewards declined, resampled reward spectrum. They again continued to visit, at least 3—4 flowers successive an enclosure where patch size...
Gut dysbiosis is commonly observed in patients with cirrhosis and chronic gastrointestinal disorders; however, its effect on antitumor immunity the liver largely unknown. Here we studied how gut microbiome affects cholangiocarcinoma. Primary sclerosing cholangitis (PSC) or colitis, two known risk factors for cholangiocarcinoma which promote tumor development mice, caused an accumulation of CXCR2+ polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC). A decrease barrier function mice...
Four common species of bumblebees in central Maine each utilized the nectar from a great variety both native and exotic flowers. The number individuals that resource was directly related to supplies available. Seasonally, ° 92% “standing crop” food energy available per day 1972. No interference competition observed, primarily exploitative. Small wild bees generally foraged at high temperatures small rewards left after Bombus exploitation. Overlap utilization guild avoided by differences...
In arctic (Kevan, 1972), temperate (Lovell, 1903), and tropical regions, the flowers of different species plants in a given habitat at any one time usually exhibit variety colors, scents, morphologies, blooming times. Bees are primary pollinators many them (Baker Hurd, 1968). Adaptations to specific (MMuller, 1881; Knuth, 1909; van der Pijl, 1961; Pijl Dodson, 1966; Grant Grant, 1965; Faegri 1971), an array generalized pollinators, or differences pollinator behavior (Macior, 1970, 1971)...
In an aviary, field—captured Black—capped Chickadees, Parus atricapillus, learned to forage preferentially at trees with either artificially or caterpillar—damaged leaves. The birds also distinguished between species of broad—leaved trees. These individuals showed differences in foraging behavior, possibly related previous conditioning the field. When captured, two were already using leaf morphology (rolls and discoloration) search for caterpillars. Two others initially disregarded instead...
The evolution of thermoregulation in endothermic animals is analyzed by asking two different but related questions: Why have evolved to regulate stable body temperatures, and why are the temperature set points generally much higher than ambient temperature? answer first question probably enzyme specialization for maintenance high activity rates. By specializing operate at specific temperatures (either or low) enzymes improve their potential promote rates substrate turnover while still...
ABSTRACT The narrow passage within the petiole between thorax and abdomen is anatomically constructed so that counter-current exchange should retain heat in despite blood flow to from cool abdomen. However, exchanger can be physiologically circumvented. Exogenously heated bumblebees prevented overheating of by shunting into They also regurgitated fluid, which helped reduce head temperature but had little effect on thoracic temperature. Temperature increases ventrum occurred steps exactly...
ABSTRACT The sphinx moth, Manduca sexta, maintained an average thoracic temperature of 40–42°C during free flight in ambient temperatures (TA) about 16·33°C. In the extremes, excess TTh over TA varied from a mean 25°C at 12·5°C, to 8°C 35°C. During tethered increased directly with TA, and 11-4°C. oxygen consumption was 45-50 c.c. Oa/g h 15 –30°C. captive 21 O2/g h. wing-beat frequency amplitude both did not vary significantly TA. same but less latter. moths showed little variation speed...