A5051868881- Aortic aneurysm repair treatments
- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Infectious Aortic and Vascular Conditions
- Diagnosis and Treatment of Venous Diseases
- Diabetic Foot Ulcer Assessment and Management
- Cerebrovascular and Carotid Artery Diseases
- Abdominal vascular conditions and treatments
- Acute Ischemic Stroke Management
- Nutrition and Health in Aging
- Renal and Vascular Pathologies
- Cardiac and Coronary Surgery Techniques
- Vascular Malformations and Hemangiomas
- Venous Thromboembolism Diagnosis and Management
- Coronary Interventions and Diagnostics
- Vascular anomalies and interventions
- Microtubule and mitosis dynamics
- Cardiac tumors and thrombi
- Wound Healing and Treatments
- Neuroendocrine Tumor Research Advances
- Myasthenia Gravis and Thymoma
- Public Administration and Political Analysis
- Systemic Lupus Erythematosus Research
National Kyushu Medical Center
2011-2025
Kyushu University
2008-2023
Ministry of Health Labour and Welfare
2020
Musashino Red Cross Hospital
2019
Pharmaceuticals and Medical Devices Agency
2016
National Hospital Organization
2011-2015
Saiseikai Yahata General Hospital
2003-2006
Job Performance Systems (United States)
2002
Arteriovenous fistulae (AVF) are the preferred vascular access for hemodialysis, but primary success rate of AVF remains poor. Successful maturation requires wall thickening and outward remodeling. A key factor determining successful is inflammation that characterized by accumulation both T-cells macrophages. We have previously shown anti-inflammatory (M2) macrophages critically important during venous remodeling; therefore, regulation macrophage may be an mechanism promoting maturation....
Herein, we report a patient who underwent stent-graft implantation using the retrograde approach for renal artery aneurysm. The was 48-year-old man total arch replacement, thoracoabdominal aortic repair, root and thoracic endovascular repair Marfan syndrome. A right aneurysm developed at prosthetic graft anastomosis during observation. First, antegrade performed. However, delivery system could not be advanced to because of kinking. Therefore, procedure discontinued. Next, used. hypochondral...
Macrophages play crucial roles in abdominal aortic aneurysm (AAA) formation through the inflammatory response and extracellular matrix degradation; therefore, regulating macrophages may suppress AAA formation. Interleukin-38 (IL-38) is a member of IL-1 family, which binds to IL-36 receptor (IL1RL2) has an anti-inflammation effect. Because express IL1RL2, we hypothesized that IL-38 suppresses by controlling macrophages. We assessed C57BL6/J mouse angiotensin II-induced model with or without...
A multidisciplinary approach is required to treat critical limb ischemia. We determined the poor prognostic factors of ischemic ulcer healing after optimal arterial revascularization, and assessed efficacy medication therapy using cilostazol, which a selective inhibitor phosphodiesterase 3.In this retrospective, single-center, cohort study, 129 limbs that underwent infrainguinal revascularization for Rutherford class 5 ischemia were reviewed. The primary end point was time revascularization....
Objectives CLI Frailty is a useful diagnostic criterion of frailty in patients with critical limb ischemia (CLI). It important to evaluate not only comorbidities but also decision making select the type treatment for patients. The purposes our study were externally validate Index and modified by measurement skeletal muscle mass using computed tomography. Methods Patients who underwent preoperative tomography examination infrainguinal revascularization between 2002 2015 retrospectively...
Background: The objective of the present study was to assess hypothesis that introduction endovascular aneurysm repair (EVAR) into Japan has expanded indication abdominal aortic (AAA) without increasing surgical mortality. Methods and Results: From 10 national hospitals, we registered a total 2,154 consecutive patients (Open surgery [OS]: n=1,577, EVAR: n=577) over 8 years, divided 4 time periods: Group I (2005–2006: n=522), II (2007–2008: n=475), III (2009–2010: n=551), IV, (2011–2012:...
Two decades have passed since therapeutic angiogenesis was proposed to promote reparative collateral growth as an alternative therapy for ischemic diseases in patients whom neither surgical revascularization nor endovascular suitable. When first began, local administration conducted using recombinant factor proteins or gene-encoding factors endothelial cells. Since then, autologous stem cells and progenitor cell transplantation been developed. Although many clinical trials performed on...
A brachial artery aneurysm (BAA) is a rare condition accounting for 5% of all peripheral arterial aneurysms. More cases true BAAs after arteriovenous fistula (AVF) closure have been reported in the past two decades.A 60-year-old man who underwent AVF renal transplantation had BAA on his left elbow that grown within 6 months. We successfully performed an open repair with end-to-end anastomosis. No complications occurred 1 year.High flow due to and some collateral factors such as use steroids...
Abstract A delay in liver regeneration after partial hepatectomy (PHx) leads to acute injury, and such delays are frequently observed aged patients. BubR1 (budding uninhibited by benzimidazole-related 1) controls chromosome mitotic segregation through the spindle assembly checkpoint, down-regulation promotes aging-associated phenotypes. In this study we investigated effects of insufficiency on mice. Low -BubR1 -expressing mutant ( L/L ) mice had a delayed recovery weight-to-body weight ratio...
Objective The present study aimed to examine which nutritional index, such as the controlling status (CONUT), prognostic index (PNI), and geriatric risk (GNRI), is better for predicting prognosis in patients with chronic limb-threatening ischemia (CLTI) following revascularization. Method We retrospectively analyzed data of who underwent revascularization CLTI between 2008 2020. endpoints were 2-year overall survival limb salvage. optimal cutoff values major amputation determined by receiver...
Inflammation plays a part in the development of abdominal aortic aneurysm (AAA), and gut microbiota affects host inflammation by bacterial translocation. The relationship between remains unknown. This study aimed to detect translocation aneurysmal wall blood patients with aneurysm, investigate effect on aneurysm. We investigated 30 from 2017 2019. analysed using highly sensitive reverse transcription-quantitative polymerase chain reaction, was next-generation sequencing. In patients,...
Early outcomes of open abdominal repair (OS) versus endovascular (EVAR) for aortic aneurysm were retrospectively analyzed, after commercialized devices EVAR had become available in Japan.A total 781 consecutive patients (OS, n = 522; EVAR, 259) treated at ten medical centers between January 2008 and September 2010. The OS group comprised with preoperative shock (SOS, 34) without (NOS, 488).Patients the 3 years older than those NOS group. There was greater prevalence hostile abdomen, on...
Aim: To assess the results of a phase I/IIa open-label dose-escalation clinical trial 5-day repeated intramuscular administration pitavastatin-incorporated poly (lactic-co-glycolic acid) nanoparticles (NK-104-NP) in patients with chronic limb threatening ischemia (CLTI).