A5101423572- Bladder and Urothelial Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Urinary and Genital Oncology Studies
- Colorectal Cancer Screening and Detection
- Circular RNAs in diseases
- Immune Cell Function and Interaction
- Prostate Cancer Diagnosis and Treatment
- Bone and Joint Diseases
- DNA Repair Mechanisms
- Hematopoietic Stem Cell Transplantation
- Orthopaedic implants and arthroplasty
- RNA modifications and cancer
- Gut microbiota and health
- Tribology and Wear Analysis
- Immune cells in cancer
- Gastric Cancer Management and Outcomes
- Molecular Biology Techniques and Applications
- RNA Research and Splicing
- Mesenchymal stem cell research
- Neonatal Respiratory Health Research
- Immune responses and vaccinations
- Folate and B Vitamins Research
Sun Yat-sen Memorial Hospital
2015-2025
Sun Yat-sen University
2012-2025
Fujian Medical University
2025
Stanford University
2021
CD8(+) TILs at different tumor sites have diverse clinical attributes, which might result from distinct microenvironments that promote differentiation into subsets. However, only a few markers been identified can define T-cell CD103 is marker of tissue resident memory T cells. In this retrospective study we investigated the cellular source and significance expression in urothelial cell carcinoma bladder tissues situ.Immunohistochemistry immunofluorescence were used to identify tissues....
Drugs blocking programmed death ligand‐1 ( PD ‐L1) have shown unprecedented activity in metastatic and unresectable bladder cancer. The purpose of the present study was to investigate expression, clinical significance association ‐L1 with tumor‐infiltrating lymphocytes TIL ) resectable urothelial cell carcinoma UCB ). In this retrospective study, 248 patients who received radical cystectomy or transurethral resection were examined. Immunohistochemistry used evaluate expression stromal CD 8 +...
Abstract Heterogeneous nuclear ribonucleoprotein K (hn RNPK ) is an essential RNA ‐ and DNA ‐binding protein that regulates diverse biological events, especially transcription. hn overexpression related to tumorigenesis in several cancers. However, both the expression patterns mechanisms of bladder cancer are unclear. We investigated by immunohistochemistry 188 patients with cancer, found levels were significantly increased tissues high‐hn was closely correlated poor prognosis. Loss‐...
Lymphocytic infiltrates are predominantly distributed in the tumour stroma, and represents tumour-related immune response. The aim of this study was to elucidate prognostic value stromal lymphocytic (SLI) resectable urothelial carcinoma bladder (UCB).The significance SLI UCB assessed a discovery cohort (n = 226; 60 deaths) validation 417; 103 deaths). categorised into intense (≥50% SLI) non-intense (<50% SLI). A multivariable Cox model used analyse associations score with overall survival...