A5101729854- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- RNA Interference and Gene Delivery
- Graphene and Nanomaterials Applications
- Bone Tissue Engineering Materials
- Nerve injury and regeneration
- Anesthesia and Sedative Agents
- Hydrogels: synthesis, properties, applications
- Antibiotics Pharmacokinetics and Efficacy
- Pluripotent Stem Cells Research
- Orthopedic Infections and Treatments
- Virus-based gene therapy research
- Cardiac and Coronary Surgery Techniques
- biodegradable polymer synthesis and properties
- Neurogenesis and neuroplasticity mechanisms
- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Silk-based biomaterials and applications
- Veterinary Pharmacology and Anesthesia
- Cancer Research and Treatments
- Nanopore and Nanochannel Transport Studies
- Surgical site infection prevention
- Wound Healing and Treatments
- Immune cells in cancer
Samsung (South Korea)
2023
Emory University
2017-2020
Veterans Health Administration
2018-2020
Georgia Institute of Technology
2020
Wake Forest University
2012-2017
Forest Institute
2012-2017
Tokyo Women's Medical University
2016
Catholic University of Korea
2007-2014
Korea Research Institute of Chemical Technology
2007-2011
Hallym University
2002-2003
The sol-to-gel transition occurring at around body temperature makes the MPEG-PCL diblock copolymer an ideal candidate material for use as injectable in situ–forming gel containing human adipose tissue–derived stem cells (hADSCs). sol can be prepared room temperature, and forms temperature. Solutions of hADSCs osteogenic factors injected into rats formed scaffolds injection sites. gels thus showed interconnective pore structure required to support growth, proliferation, differentiation...
We herein formulated and characterized an in situ–forming chitosan gel consisting of glycerol phosphate (GP) disodium salt, examined its use as vivo scaffold for rat bone marrow mesenchymal stem cells (rBMSCs). First, the phase transition behaviors solutions with without GP were a function temperature. Chitosan containing > 20 wt% became at 37°C maintained this form 28 days vitro vivo. Next, we whether could act suitable biocompatible substrate attachment proliferation rBMSCs....
Appropriate surface wettability and roughness of biomaterials is an important factor in cell attachment proliferation. In this study, we investigated the correlation between roughness, biological response human adipose-derived stem cells (hADSCs). We prepared wettable rough gradient polyethylene (PE) surfaces by increasing power a radio frequency corona discharge apparatus with knife-type electrodes over moving sample bed. The PE changed gradually from hydrophobic smooth to hydrophilic...
Using a complete spinal cord transection model, the present study employed combinatorial strategy comprising rat bone marrow stem cells (rBMSCs) and polymer scaffolds to regenerate neurological function after injury (SCI) of different lengths. SCI models with completely transected lesions were prepared by surgical removal 1 mm (SC1) or 3 (SC3) lengths in eighth-to-ninth vertebrae, procedure that resulted bilateral hindlimb paralysis. A cylindrical poly(D,L-lactide-co-glycolide)/small...
Bone marrow derived mesenchymal stem cells (MSCs) are regularly utilized for translational therapeutic strategies including cell therapy, tissue engineering, and regenerative medicine frequently used in preclinical mouse models both mechanistic studies screening of new based therapies. Current methods to culture murine MSCs (mMSCs) select rapidly dividing colonies require long-term expansion. These thus months generate sufficient numbers feasibility a lab setting the populations often have...
We herein formulated and characterized an in situ–forming chitosan gel consisting of glycerol phosphate (GP) disodium salt, examined its use as vivo scaffold for rat bone marrow mesenchymal stem cells (rBMSCs). First, the phase transition behaviors solutions with without GP were a function temperature. Chitosan containing > 20 wt% became at 37°C maintained this form 28 days vitro vivo. Next, we whether could act suitable biocompatible substrate attachment proliferation rBMSCs....
In this study, we examined the use of polyethyleneimine (PEI) as a non-viral gene carrier and lipofectamine(trade mark) 2000 control for rat pheochromocytoma PC-12 cells. The complex formation PEI DNA or lipofectamine was characterized by gel electrophoresis measurement particle size surface charge. A gradual increase in charge (from 0.7 to 43 mV) decrease 900 130 nm) observed PEI-DNA with higher concentrations. cytotoxicity cells lipofectamine-DNA similar at N:P ratios 4 8. Transfection...
A new synthetic small molecule, compound 1, which induced a neuronal differentiation from mesenchymal stem cells (MSCs) with an excellent efficiency, was identified. Furthermore the differentiated cell by 1 showed neural electrophysiological and cholinergic neuron properties.
Rat bone marrow stem cells (rBMSCs) in the presence of chemical molecules were differentiated into neurons.
This study aimed to investigate the effect of lower-extremity strengthening exercise (LSE) with and without blood flow restriction (BFR) on left thigh golf performance. Eighteen amateur golfers more than 1 year experience participated in were randomly divided into two groups: LSE+BFR group (LSE BFR thigh, n = 9) LSE BFR, 9). The LSEs consisted squats, lunges, standing leg curls. All exercises performed 3 times a week for 6 weeks. Changes muscle strength, plantar foot pressure (weight...
Methoxy poly(ethylene glycol) (MPEG)-b-poly(ε-caprolactone) (PCL) diblock copolymer was synthesized by ring-opening of ε-caprolactone (ε-CL) in the presence a monomer activator with terminal alcohol MPEG as an initiator. The temperature sensitive behavior prepared MPEG-PCL solution examined. polymer formed translucent sol at room temperature. As increased from temperature, became gel, indicating that can form gel body Brain-derived neurotrophic factor (BDNF) loaded and Pluronic for...
Our understanding of the biology ankle arthrodesis is based largely on work in spine and long bone animal models. However, local soft tissue vascular anatomy foot different from that spine. Accordingly, objective this study was to develop a small model.A total 12 Lewis rats successfully underwent with stabilization consisting single Kirschner wire across prepared tibiotalar joint. Based high nonunion rates initial procedure, modification made second pin crossing A 6 procedure. Radiographs...
You have accessJournal of UrologyTransplantation & Vascular Surgery II1 Apr 2014MP72-08 CELLULARIZED ELECTROSPUN VASCULAR GRAFTS FOR RENAL ARTERY RECONSTRUCTION Hyunhee Ahn, Young Miin Ju, Cheil Kim, John D. Jackson, James J. Yoo, Sang Jin Lee, and Anthony Atala AhnHyunhee Ahn More articles by this author , JuYoung Ju KimCheil Kim JacksonJohn Jackson YooJames Yoo LeeSang Lee AtalaAnthony View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.2247AboutPDF ToolsAdd to...