A5084258489- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Molecular Sensors and Ion Detection
- Biosensors and Analytical Detection
- Luminescence and Fluorescent Materials
- Analytical Chemistry and Sensors
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Molecular Junctions and Nanostructures
- Conducting polymers and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Quantum Dots Synthesis And Properties
- interferon and immune responses
- Advanced Nanomaterials in Catalysis
- Peptidase Inhibition and Analysis
- Nanocluster Synthesis and Applications
- RNA Interference and Gene Delivery
- Cancer Research and Treatments
- Mercury impact and mitigation studies
- Advanced Fiber Laser Technologies
- Adsorption, diffusion, and thermodynamic properties of materials
- Cancer Immunotherapy and Biomarkers
- Heme Oxygenase-1 and Carbon Monoxide
Soochow University
2023-2025
Wannan Medical College
2013-2025
First Affiliated Hospital of Soochow University
2024-2025
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
2023-2024
Soochow University
2024
Anhui Normal University
2013-2016
Shandong University
2014
Biology Institute of Shandong Academy of Sciences
1997
Jinan University
1996
Abstract Immunotherapy has received widespread attention for its effective and long‐term tumor‐eliminating ability. However, immunogenic “cold” tumors, such as prostate cancer (PCa), the low immunogenicity of tumor itself is a serious obstacle to efficacy. Here, this work reports strategy enhance PCa by triggering cascade self‐enhanced ferroptosis in cells, turning from “hot”. This develops transformable self‐assembled peptide TEP‐FFG‐CRApY with alkaline phosphatase (ALP) responsiveness...
Prostate cancer (PCa) is a frustrating immunogenic "cold" tumor and generally receives unsatisfied immunotherapy outcomes in the clinic. Pyroptosis an excellent cell death form that can effectively activate antitumor immune response, promote cytotoxic T-lymphocyte infiltration, convert tumors from to "hot." However, vivo application of pyroptosis drugs seriously limited, upregulation PD-L1 caused by photo-immunotherapy further promotes escape. Herein, new nano-photosensitizer (YBS-BMS...
A photoelectrochemical sensor for detecting theophylline was exploited based on electrodes modified with polydopamine–gold nanocomposite. The exhibited remarkable photoelectric catalytic capability towards oxidation.
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Herein, a method was developed for the sensitive monitoring of carcinoembryonic antigen (CEA) by gold nanoparticles dotted prussian blue@polyaniline core-shell nanocubes (Au NPs/PB@PANI). First, facile low-temperature used to prepare uniform PB@PANI with assistance PVP, where PB acted as electron transfer mediator provide electrochemical signals, and PANI excellent conductivity desirable chemical stability not only played role protective layer prevent etching in basic media but also...
The development of a specifically sensitive approach for CA15-3 detection is great significance the early diagnosis and treatment monitoring breast cancer. In present work, an electrochemiluminescence (ECL) immunosensor was constructed selective based on dual-quenching strategy. Ru(dcbpy)32+, poly(ethylenimine) (PEI), gold nanoparticles (AuNPs) were immobilized dendritic mesoporous silica (DMSNs) (Ru-PEI/AuNPs@DMSNs) with high ECL efficiency due to loading amounts shortened electron-transfer...
Prostate cancer presents as a challenging disease, it is often characterized an immunologically "cold" tumor, leading to suboptimal outcomes with current immunotherapeutic approaches in clinical settings. Photodynamic therapy (PDT) harnesses reactive oxygen species generated by photosensitizers (PSs) disrupt the intracellular redox equilibrium. This process induces DNA damage both mitochondria and nucleus, activating of immunogenic cell death (ICD) cGAS-STING pathway. Ultimately, this...
In this work, we have developed a novel visual Hg2+ sensor in aqueous solution using unmodified Au@Ag core–shell nanoparticles at room temperature, based on redox reaction between Ag-shell and Hg2+. The prepared exhibited good monodispersity. the presence of Hg2+, was reduced into Hg (0) by Ag-shell, deposited surface Au-core to form Au–Hg alloys caused aggregation, leading color changes from yellow purplish red, plasmon resonance spectra red shift. Under optimal conditions, could...
A simple, sensitive, and fluorescent immunoassay for the detection of prostate-specific antigen (PSA) based on horseradish peroxidase silicon dioxide nanospheres as a signal amplification strategy has been described. In design, primary antibody (Ab1) PSA was first immobilized 96-well plates via physical adsorption between polystyrene hydrophobic groups molecule. The (SiO2 NSs), with large surface area good biocompatibility, were loaded (HRP) peroxidase-labeled secondary antibodies (HRP-Ab2)...
This work reports the first study on detection of dobutamine (DBTM) using magnesium oxide microflowers–nafion composite. Owing to large surface area and strong adsorption ability, composite exhibits excellent electrocatalytic activity toward DBTM, revealing a linear range 1.0–30 μM with limit 0.092 (3σ method).
Fluoroimmunoassay for simultaneous detection of CEA and AFP.