A5060207316- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetic Foot Ulcer Assessment and Management
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Ovarian cancer diagnosis and treatment
- Advanced X-ray and CT Imaging
- Renal and Vascular Pathologies
- Diagnosis and Treatment of Venous Diseases
- Receptor Mechanisms and Signaling
- Cardiac and Coronary Surgery Techniques
- Fatty Acid Research and Health
- Cardiovascular Function and Risk Factors
- Atherosclerosis and Cardiovascular Diseases
- Angiogenesis and VEGF in Cancer
Gifu Heart Center
2023-2024
Katsumata Hospital
2023
JR Tokyo General Hospital
2017-2022
Nitobe Memorial Nakano General Hospital
2020
Saiseikai Yokohama Eastern Hospital
2010-2019
Boston Scientific (United States)
2018
Meguro Parasitological Museum
2016
Shonan Kamakura General Hospital
2016
Tenri Hospital
2009-2015
Saiseikai Fukuoka General Hospital
2014-2015
Background— The influences of antiplatelet therapy discontinuation on the risk stent thrombosis and long-term clinical outcomes after drug-eluting implantation have not yet been addressed adequately. Methods Results— In an observational study in Japan, 2-year were assessed 10 778 patients undergoing sirolimus-eluting implantation. Data status during follow-up collected prospectively. Incidences definite 0.34% at 30 days, 0.54% 1 year, 0.77% 2 years. Thienopyridine use was maintained 97%,...
Background: Procedural results for percutaneous coronary intervention (PCI) in vessels with chronic total occlusion (CTO) have improved recent years, and PCI strategies moved toward more complete revascularization liberal use of CTO-PCI. However, evidence evaluating CTO-PCI is limited to observational studies small clinical trials. Methods: In this open-label, multicenter, randomized, noninferiority trial, PCI-eligible patients were assigned receive either 1 2 strategies: or no the...
Theoretically, bioresorbable vascular scaffolds (BVSs) may provide superior long-term results compared with permanent metallic drug-eluting stents (DESs). However, whether BVSs are as safe and effective DESs prior to complete bioresorption is unknown. ABSORB Japan was a single-blind, multicentre, active-controlled, randomized trial designed support regulatory approval of the Absorb BVS in Japan. Eligible patients one or two de novo lesions different epicardial vessels were at 38 Japanese...
There is a scarcity of long-term data from large-scale drug-eluting stent registries with large enough sample to evaluate low-frequency events such as thrombosis (ST).Five-year outcomes were evaluated in 12 812 consecutive patients undergoing sirolimus-eluting (SES) implantation the j-Cypher registry. Cumulative incidence definite ST was low (30 day, 0.3%; 1 year, 0.6%; and 5 years, 1.6%). However, late very continued occur without attenuation up years after (0.26%/y). target lesion...
Prediction of thrombotic and bleeding risk is important to optimize antithrombotic therapy after percutaneous coronary intervention.We developed the prediction rules for events separately in Japanese patients. Derivation validation cohorts consisted 4778 patients from CREDO-Kyoto (Coronary Revascularization Demonstrating Outcome Study Kyoto) registry cohort 2 4669 RESET (Randomized Evaluation Sirolimus-Eluting Versus Everolimus-Eluting Stent Trial) NEXT (Nobori Biolimus-Eluting Xience/Promus...
NEXT (NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-Eluting Stent Trial) was designed for evaluating the noninferiority of a biolimus-eluting stent (BES) relative to an everolimus-eluting (EES) in terms target lesion revascularization (TLR) at 1 year.Efficacy and safety data comparing biodegradable polymer BES with durable cobalt-chromium EES are currently limited.The trial is prospective, multicenter, randomized, open-label, EES. Between May October 2011, 3,235 patients were...
Objectives This registry evaluated the current trends and outcomes associated with retrograde percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). Background Since its introduction, several techniques technologies have been introduced PCI CTO. Methods Eight hundred one patients who underwent CTO in 28 Japanese centers between January 2009 December 2010 were enrolled this registry. Results Overall procedural clinical success rates 84.8 83.8%, respectively, of which,...
Objectives This study was performed to evaluate the acute outcomes of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) based on operator experience. Background Despite developments in both technology and techniques, PCI procedures CTO's remain challenging. Methods A 3,229 eligible subjects who underwent CTO‐PCI were enrolled from 56 centers by a retrograde summit using web registry system. To compare CTO data, 18 classified as higher volume (HC) 38 lower (LC)...
While primary percutaneous coronary intervention (PCI) has significantly contributed to improve the mortality in patients with ST segment elevation myocardial infarction even cardiogenic shock, PCI is a standard of care most Japanese institutions. Whereas there are high numbers available facilities providing Japan, no clear guidelines focusing on procedural aspect standardized care. Whilst updated for management acute were recently published by European Society Cardiology, following major...
We sought to investigate the timing of restenosis and factors following nitinol stenting in superficial femoral artery (SFA).Restenosis SFA remains unsolved.We analyzed 742 limbs consecutive 585 patients who underwent successful endovascular therapy for de novo lesions. Patency was assessed by duplex ultrasonography. Primary patency defined as treated vessels without secondary target reopened repeat revascularization. Receiver-operating characteristic (ROC) analysis performed delineate...
The retrograde approach to CTO is promising, but questions remain with regard its wider application and the potential risks. This study evaluated feasibility efficacy of recanalisation chronic total occlusion (CTO) coronary arteries.A 378 consecutive patients (previously failed PCI 32.0%) who enrolled in 27 institutions Japan underwent for CTO. We analysed data on lesion characteristics, procedural materials, technique used, complications clinical outcomes. Successful was achieved 70.4%...
Background —Coronary stenting improves outcomes compared with balloon angioplasty, but it is costly and may have other disadvantages. Limiting stent use to patients a suboptimal result after angioplasty (provisional angioplasty) be as effective less expensive. Methods Results —To analyze the cost-effectiveness of provisional scheduled for single-vessel were first randomized receive primary (97 patients) or guided by Doppler flow velocity angiography (523 patients). Patients in latter group...
PurposeTo investigate the long-term outcomes of nitinol stenting in femoropopliteal lesions and to determine factors associated with restenosis. MethodsBetween December 2003 2009, 861 patients (603 men; mean age 72 years) underwent segment 1017 limbs. A quarter (26%) had critical limb ischemia. Mean lesion length was 152±93 mm. Stent patency assessed by either duplex ultrasound or angiography analyzed Kaplan-Meier estimation. The determinants restenosis were explored Cox proportional hazard...
This study was performed to determine the complications occurring during retrograde percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) based on analysis of multicenter, prospective, nonrandomized Retrograde Summit registry.Retrograde PCI CTO has improved treatment success rates, but several related approach have been reported, including collateral channel injury and donor artery due their use as roots.This registry included data from 1,166 patients who underwent in 28...
Background— There is a paucity of data reporting the clinical outcomes biodegradable polymer biolimus-eluting stent (BP-BES) compared with durable everolimus-eluting (DP-EES) beyond 1 year after implantation when fully degraded. Methods and Results— The NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-Eluting Stent Trial (NEXT) prospective, multicenter, randomized, open-label, noninferiority trial comparing BP-BES DP-EES in patients scheduled for percutaneous coronary intervention...
Background —The purpose of this study was to compare long-term outcomes coronary stenting in all lesions (elective stenting) or only with inadequate morphological and functional results after balloon angioplasty (guided PTCA). Methods Results —Treatment multivessel disease, any lesion length vessel size, allowed provided that were suitable for stent implantation. Patients randomized elective implantation (n=370) guided PTCA (n=365). An optimal result (residual diameter stenosis ≤35%, flow...