- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Advanced X-ray and CT Imaging
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Cardiovascular Effects of Exercise
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac electrophysiology and arrhythmias
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Dermatological and COVID-19 studies
- Vascular anomalies and interventions
- Medical Imaging Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Skin Diseases and Diabetes
- Coronary Artery Anomalies
- Cardiovascular and exercise physiology
- Neurological and metabolic disorders
University of British Columbia
2012-2023
St. Paul's Hospital
1998-2023
Toronto Public Health
2013-2021
St. Paul's Hospital
2010-2018
Hôpital Notre-Dame
2017
Université de Montréal
2017
Lung Institute
2010
Vancouver General Hospital
1998
The purpose of our study was to determine the effect Adaptive Statistical Iterative Reconstruction (ASIR) on cardiac CT angiography (CTA) signal, noise, and image quality.We evaluated 62 consecutive patients at three sites who underwent clinically indicated CTA using an ASIR-capable 64-MDCT scanner a low-dose technique. Studies were reconstructed filtered back projection (FBP), ASIR-FBP composites 20-80% ASIR, 100% ASIR. signal noise measured in aortic root each four coronary arteries. Two...
The objective of our study was to assess the impact Adaptive Statistical Iterative Reconstruction (ASIR) on radiation dose and quality for coronary CT angiography (CTA).We prospectively evaluated 574 consecutive patients undergoing CTA at three centers. Comparisons were performed between groups initially using filtered back projection (FBP) (n = 331) subsequently ASIR 243) with regard patient scan characteristics, dose, diagnostic quality.There no difference in use prospective gating, tube...
Prospectively ECG-triggered coronary CT angiography images are acquired during a window in middiastole. Additional surrounding x-ray beam on time, or padding, can be variably set, and the increased padding results additional available phases for analysis. The purpose of this study was to assess effect duration image interpretability its incident radiation dose.We prospectively evaluated imaging 886 patients undergoing consecutive angiographic examinations at three centers compared findings...
Abstract Objectives Many patients with atrial fibrillation ( AF ) are not candidates for rhythm control and may require rate control, typically beta‐blocking BB or calcium channel blocking CCB agents. Although these appear to have a low 30‐day of stroke death, it is unclear if one class agent safer more effective. The objective was determine whether s would lower hospital admission measure safety outcomes including stroke, emergency department (ED) revisits. Methods This retrospective cohort...
Coronary CT Angiography of Patients With a Normal Body Mass Index Using 80 kVp Versus 100 kVp: A Prospective, Multicenter, Multivendor Randomized TrialTroy M. LaBounty1 2, Jonathon Leipsic3 4, Rohan Poulter3, David Wood3, Mark Johnson3, Monvadi B. Srichai5, Ricardo C. Cury6, Brett Heilbron3, Cameron Hague4, Fay Y. Lin7, Carolyn Taylor3, John R. Mayo4, Yogesh Thakur4, James P. Earls8, G. Mancini3, Allison Dunning1, Millie J. Gomez1 and K. Min1 2Audio Available | Share
In non-emergency department (ED) settings, women with atrial fibrillation and flutter (AFF) have different presentations, treatments, outcomes than men: they are older, less likely to be treated rhythm control strategies or appropriate anticoagulation, more strokes. This has not been investigated in ED patients.Records from consecutive patients January 1 December 31, 2009, electrocardiogram-proven AFF at two urban hospitals were collected. Review of administrative clinical data identified...
Underlying coronary artery disease (CAD) is the primary cause of sudden cardiac death in masters athletes (>35 years). Preparticipation screening may detect cardiovascular disease; however, optimal method undefined this population. The Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and American Heart Association (AHA) Screening are often currently used; a more comprehensive risk assessment be required. We sought to ascertain assess effectiveness tools athletes.This...
To assess the prevalence, extent, severity, and risk of coronary artery disease (CAD) in patients suspected having CAD but with no medically modifiable factors.Institutional review board approval or waiver consent was obtained at each center. This study HIPAA compliant. From an international multicenter cohort 27 125 subjects undergoing computed tomographic (CT) angiography from 12 centers, 5262 without known factors were identified. severity defined as none (0%), mild (1%-49%), obstructive...
A Prospective Randomized Controlled Trial to Assess the Diagnostic Performance of Reduced Tube Voltage for Coronary CT AngiographyJonathon Leipsic1 2, Troy M. LaBounty3, G. B. John Mancini2, Brett Heilbron2, Carolyn Taylor2, Mark A. Johnson1, Cameron Hague1, James P. Earls4, Amr Ajlan1 and K. Min3 5Audio Available | Share
The relative effectiveness of medical therapy compared with a conservative approach monitoring in patients idiopathic frequent premature ventricular complexes (PVCs) is uncertain. We evaluated the versus for PVCs.Patients PVCs (≥5%) were prospectively enrolled this cohort study between 2016 and 2020. In normal cardiac function no structural heart disease, those receiving controls without therapy. Patients followed longitudinally change PVC burden serial echocardiography.Overall, 120 met...
Deep brain stimulation (DBS) is increasingly used to treat a variety of neurological conditions (e.g. movement disorders and chronic pain). This prospective study was designed detect electrocardiogram (ECG) artifacts induced by deep investigate which factors (patient disease, electrode position within the or type stimulation) produced these artifacts.Twelve patients (four women, eight men) with stimulators were enrolled in study. Patients selected represent common indications for DBS...