A5048471761- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Thyroid Cancer Diagnosis and Treatment
- Diabetes Treatment and Management
- Cytokine Signaling Pathways and Interactions
- Reproductive Biology and Fertility
- Plant Molecular Biology Research
- Endometriosis Research and Treatment
- Genetic Mapping and Diversity in Plants and Animals
- Biochemical Analysis and Sensing Techniques
- Regulation of Appetite and Obesity
- Lipoproteins and Cardiovascular Health
- Traditional Chinese Medicine Analysis
- Metabolism, Diabetes, and Cancer
- Lung Cancer Treatments and Mutations
- Plant Stress Responses and Tolerance
- Inflammasome and immune disorders
- Adipose Tissue and Metabolism
- RNA modifications and cancer
- Adrenal and Paraganglionic Tumors
- Uterine Myomas and Treatments
- Thyroid and Parathyroid Surgery
- Plant biochemistry and biosynthesis
- Neurogenesis and neuroplasticity mechanisms
Huazhong University of Science and Technology
2022-2025
Tongji Hospital
2022-2025
Suzhou Traditional Chinese Medicine Hospital
2015-2024
Nanjing University of Chinese Medicine
2013-2024
Peking University Shenzhen Hospital
2007-2024
Zhejiang University
2011-2024
Nanjing Agricultural University
2018-2024
Central South University
2017-2024
Sir Run Run Shaw Hospital
2017-2024
Minzu University of China
2024
N
After ovulation, metaphase II oocytes undergo a time-dependent deterioration in vivo or vitro, which is referred to as postovulatory oocyte aging, process during series of deleterious molecular and cellular changes occur. In this study, we found that short-term injection resveratrol (3,5,4'-trihydroxystilbene) effectively ameliorated oxidative stress-induced damage aging middle-aged mice vivo. Resveratrol induced delayed the aging-induced including elevated expression anti-aging molecule...
For efficient plant reproduction, seed dormancy delays germination until the environment is suitable for next generation growth and development. The phytohormone abscisic acid (ABA) plays important role in induction maintenance of dormancy. Previous studies have identified that WRKY transcription factors can regulate ABA signaling pathway. Here, we an Oswrky29 mutant with enhanced a screen T-DNA insertion population. OsWRKY29 member factor family which located nuclear. genetic analyses...
Mesenchymal stem cell (MSC) transplantation is a promising treatment for ischemia-reperfusion injury (IRI). However, its effects on hepatic IRI were not consistent in the previous studies. 3D spheroid-cultured MSCs enhance their production of trophic and anti-inflammatory properties, but remain unclear. In this study, we compared human umbilical derived (3D UC-MSCs) with 2D-cultured UC-MSCs (2D treating IRI. The RNA sequencing data showed that suppression mitosis, response to hypoxia,...
The endosomal sorting complex required for transport (ESCRT) is highly conserved in eukaryotic cells and plays an essential role the biogenesis of multivesicular bodies cargo degradation to plant vacuole or lysosomes. Although ESCRT components affect a variety growth development processes, their impact on leaf rarely reported. Here, we found that OsSNF7.2, ESCRT-III component, controls rolling rice (Oryza sativa). Ossnf7.2 mutant rolled 17 (rl17) has adaxially leaves due decreased number...
Cryptotanshinone (CT), one major lipophilic component isolated from Salvia miltiorrhiza Bunge, has shown to possess chemopreventive properties against various types of cancer cells. In this study, CT was be a potent anti-angiogenic agent in zebrafish, and mouse models could limit tumor growth by inhibiting angiogenesis. We further found that inhibit the proliferation, migration, angiogenic sprouting, tube formation HUVECs. addition, we demonstrated lower level TNF-α due destabilization mRNA,...
Heading date is an important agronomic trait affecting crop yield. The GRAS protein family a plant-specific super extensively involved in plant growth and signal transduction. However, proteins are rarely reported have role regulating rice heading date. Here, we report DHD1 (Delayed Date1) delays enhances yield rice. Biochemical assays showed physically interacts with OsHAP5C/D both vitro vivo. located the nucleus that rhythmic expression. Both affect by expression of Ehd1. We propose to...
Polysaccharides extracted from Lycium barbarum (LBPs) possess a wide variety of biological activities. However, their neuroprotective effects have not yet been fully elucidated. The aim the present study was to investigate inhibitory LBPs on production lipopolysaccharide (LPS)‑induced proinflammatory mediators in BV2 microglia. mouse microglial cells were cultured and an MTT assay performed determine whether had effect apoptosis LPS-stimulated cells. Our data showed that LPS induced...