A5075827785- Perovskite Materials and Applications
- Conducting polymers and applications
- Solid-state spectroscopy and crystallography
- Chalcogenide Semiconductor Thin Films
- Organic Light-Emitting Diodes Research
- Heat Transfer and Boiling Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Metal Alloys Wear and Properties
- Surface Treatment and Residual Stress
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Engineering Applied Research
- Cardiac Valve Diseases and Treatments
- DNA and Nucleic Acid Chemistry
- Zebrafish Biomedical Research Applications
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Organic Electronics and Photovoltaics
- Erosion and Abrasive Machining
- Synthetic Organic Chemistry Methods
- Optical properties and cooling technologies in crystalline materials
- Inflammasome and immune disorders
- Mechanical Circulatory Support Devices
- Nanoparticles: synthesis and applications
- Fluid Dynamics and Heat Transfer
Osaka Gas (Japan)
2022-2025
Saku Central Hospital
2019-2025
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
2024
Harvard University
2023-2024
Boston Children's Hospital
2023-2024
Dana-Farber/Harvard Cancer Center
2023-2024
Nagoya University
2001-2023
City Hospital
2023
Shimane University Hospital
2023
Chikamori Hospital
2023
Plasma membrane perforation elicited by caspase cleavage of the gasdermin D (GSDMD) N-terminal domain (GSDMD-NT) triggers pyroptosis. The mechanisms underlying GSDMD translocation and pore formation are not fully understood. Here, using a proteomic approach, we identified fatty acid synthase (FASN) as GSDMD-binding partner. S-palmitoylation at Cys
Cellular responses to injury are crucial for complete tissue regeneration, but their underlying processes remain incompletely elucidated. We have previously reported that myeloid-defective zebrafish mutants display apoptosis of regenerative cells during fin fold regeneration. Here, we found the phenotype is induced by prolonged expression interleukin 1 beta (il1b). Myeloid considered be principal source Il1b, show epithelial express il1b in response and initiate inflammatory response, its...
Gasdermin D (GSDMD)-mediated macrophage pyroptosis plays a critical role in inflammation and host defense. Plasma membrane perforation elicited by caspase-cleaved GSDMD N-terminal domain (GSDMD-NT) triggers rupture subsequent pyroptotic cell death, resulting release of pro-inflammatory IL-1β IL-18. However, the biological processes leading to its translocation pore formation are not fully understood. Here, using proteomics approach, we identified fatty acid synthase (FASN) as GSDMD-binding...
The effects of guanidinium iodide surface treatment (GST) on CH3NH3PbI3 perovskite solar cells with decaphenylcyclopentasilane (DPPS) were investigated. GST decreases the carrier trap density and improves photovoltaic characteristics. X-ray diffraction results showed that lattice constants crystals increased by insertion into methylammonium defects. thermal stability unlaminated devices was tested in air at 85°C. device prepared using exhibited highest conversion efficiency. First-principles...
First-principles electronic band calculations were used to investigate the effects of alkali metals and organic cations added Cu-based perovskite solar cells. The copper d-orbital was slightly above valence-band maximum functioned as an acceptor level for carrier generation. Excitation from iodine p-orbitals d-orbitals metal s-orbitals could suppress recombination promote transport. Experimental conversion efficiencies increased after adding both Cu Na, in agreement with calculations....
Molecular hydrogen ameliorates pathological states in a variety of human diseases, animal models, and cell but the effects on cancer have been rarely reported. In addition, molecular mechanisms underlying remain mostly unelucidated. We found that enhances proliferation four out seven lines (the responders). The proliferation-promoting were not correlated with basal levels cellular reactive oxygen species. Expression profiling cells showed responders higher gene expression mitochondrial...
Abstract To avoid formation of the photo-inactive δ -phase formamidinium-cesium lead triiodide, copper or germanium was added to perovskite compounds stabilize photoactive α -phase. It found that substitution by (Ge) (Cu) provided stabilization in present work. The first-principles molecular dynamics calculations indicated displacements formamidinium molecules were suppressed Ge doping. X-ray diffraction results Cu doping could be effective for suppression phase transition from -
Abstract Experiments and first-principles calculations were performed to investigate the effects of Cu substitution in CH 3 NH PbI perovskite crystals. The indicated that energy level d orbital formed above VB maximum would be an acceptor or defect level. effect addition on device properties was investigated, with added 2% provided higher efficiencies than standard device. On other hand, decrease short-circuit current density increasing content attributed orbitals. First-principles...
Abstract In clinical studies, the next-generation anti-tumor necrosis factor-alpha (TNF-α) single domain antibody ozoralizumab showed high efficacy shortly after subcutaneous injection. To elucidate mechanism underlying rapid onset of effects ozoralizumab, we compared biodistribution kinetics and adalimumab injection in an animal model arthritis. Alexa Fluor 680-labeled were administered by once (2 mg/kg) at five weeks induction collagen-induced arthritis (CIA) model. The time-course changes...
The effects of guanidinium (C(NH2)3, GA) and cesium (Cs) co-additions on methylammonium lead iodide (CH3NH3PbI3, MAPbI3) perovskite solar cells were investigated. first-principles calculations the density states band structures showed a reduction in total energy by GA addition. Although calculation that co-addition GA/Cs to MAPbI3 could decrease carrier mobilities, addition improved device performance. This result would be due facilitation grain growth suppression defects from changes...
Effects of substitution halogen anions and addition alkali metal cations for guanidinium (GA)-ethylammonium (EA) hybrid-doped perovskite solar cells were investigated by fabricating devices comparing their photovoltaic properties. The compositions the additives found to contribute improvement preferred orientations crystals, order effectiveness was I, Cl, Br. In addition, contributed conversion efficiencies, 3 % cesium at CH3NH3 site most effective. It also that short-circuit current...
Perovskite solar cells have attained high photoconversion efficiencies by changing chemical compositions of the perovskites and layered structures devices. However, perovskite compounds easily decompose in air atmosphere even at room temperature, photovoltaic properties are degraded formed defects. The motivation this work is to solve these instability problems, objective present improve film quality introducing lanthanide elements decaphenylcyclopentasilane (DPPS), which were expected...
Abstract Background Left bundle branch area pacing (LBBAP) is widely performed in routine clinical practice. Achieving LBBAP requires deep insertion of the lead into interventricular septum. may be challenging patients with a history open‐heart surgery (OHS) because myocardial fibrosis associated surgical trauma. This study aimed to report feasibility and safety performing OHS. Methods retrospective analysis included who underwent successful between November 2020 September 2024, approval...
Perovskite solutions with added potassium iodide (KI) and ethylammonium bromide (EABr) were used to fabricate perovskite solar cells in ordinary air at 190 °C. The addition of EABr KI induced (100)-oriented crystals, which resulted the improvement short-circuit current densities conversion efficiencies. density, open circuit voltage, efficiency best device 21.0 mA cm−2, 0.942 V, 12.88%, respectively. First-principles calculations also indicated a decrease total energy per cell an increase...
Perovskite photovoltaic devices added with tin (Sn) dichloride and copper (Cu) bromide were fabricated characterized. The thin film prepared by an ordinary spin-coating technique using air blowing method in ambient air. A decaphenylcyclopentasilane layer was coated at the surface of perovskite annealed a high temperature 190 °C. Conversion efficiencies short-circuit current densities improved for Sn Cu compared standard devices. energy gap crystal decreased through addition, which also...