A5078209440- Craniofacial Disorders and Treatments
- Orthodontics and Dentofacial Orthopedics
- Dental Radiography and Imaging
- Cleft Lip and Palate Research
- Temporomandibular Joint Disorders
- Simulation and Modeling Applications
- Anatomy and Medical Technology
- Peptidase Inhibition and Analysis
- Medical and Biological Sciences
- Facial Rejuvenation and Surgery Techniques
- Dental Implant Techniques and Outcomes
- Lung Cancer Research Studies
- Tracheal and airway disorders
- Complex Network Analysis Techniques
- Cancer Mechanisms and Therapy
- Computer Graphics and Visualization Techniques
- Obstructive Sleep Apnea Research
- Congenital Diaphragmatic Hernia Studies
- Facial Trauma and Fracture Management
- Glaucoma and retinal disorders
- Cerebrovascular and Carotid Artery Diseases
- Innovative Educational Techniques
- Transportation Planning and Optimization
- dental development and anomalies
- Natural Language Processing Techniques
Jilin Province Tumor Hospital
2016-2025
Peking University
2014-2025
Stomatology Hospital
2015-2024
Center for High Pressure Science & Technology Advanced Research
2024
Shanghai Zhangjiang Laboratory
2024
Fudan University
2024
Amazon (United States)
2024
The University of Queensland
2019-2023
King University
2002-2022
National University of Defense Technology
2007-2018
Abstract Background The aim of this study was to evaluate the efficacy fluorine 18 ( F) labeled fibroblast activation protein inhibitor (FAPI) in identifying mediastinal and hilar lymph node metastases develop a model quantitatively repeatedly identify status. Methods Twenty-seven patients with 137 nodes were identified by two PET/CT images. sensitivity, specificity, accuracy, positive predictive value (PPV), negative (NPV) status analyzed, optimal cut-off ROC analysis. Results SUVmax...
Maxillary hypoplasia is a familiar deformity in patients with cleft lip and palate. A large amount of maxilla advancement often needed to correct the severe deformity, but local soft-tissue scars around restrict increase relapse rate. By gradually lengthening both bones soft tissues, midface distraction can greatly postoperative stability lower rate.Ten maxillary secondary palate were treated using three kinds internal devices. Among them, six received an alveolar bone graft from iliac crest...
The aim of this study was to investigate the genetic basis and pathogenic mechanism variable maculopathies, ranging from mild photoreceptor degeneration central areolar choroidal dystrophy, in a five-generation family.Clinical characterizations, whole-exome sequencing, genome-wide linkage analysis were carried out on family. Zebrafish models used pathogenesis GUCA1A mutations.A novel mutation, p.R120L, identified family predicted alter tertiary structure guanylyl cyclase-activating protein...
Objective To describe the morphological changes of velopharyngeal components in patients with cleft lip and palate after Le Fort I osteotomy maxillary advancement to clarify whether are related distance advancement. Design Retrospective case series. Setting Hospital Stomatology Unit Peking University, Beijing, China. Patients A total 47 hypoplasia secondary palate. Interventions combined bilateral sagittal split ramus and/or genioplasty for treatment maxillofacial deformity. Main Outcome...
A gradient boosting procedure in combination with hierarchical reconciliation is proposed this study for short-term forecasting of traffic flow. Particular attention paid to three main characteristics flow: the temporal and spatial patterns, interactions between dynamics flow at different aggregation levels. The performance framework examined by comparing it frequently used methods (i.e., SARIMA, Kalman filter model random forest) literature, using distinctive datasets. Overall, based...
A series of experimental studies were performed in monkeys to study the effect mandibular distraction osteogenesis on inferior alveolar nerve at different times before and after distraction. mandible osteotomy was carried out unilaterally 10 young rhesus bilaterally six. The intact nerves contralateral side used for control. Care taken avoid destroying integrity during surgical procedure. After a 5-day latency period, device activated rate 0.5 mm twice each day 15 days. Sensory action...
The authors report the use of novel individualized surgical templates and titanium miniplates for Le Fort I osteotomy evaluate accuracy this technique in vitro. Nine three-dimensional stereolithographic skull models were used to design microplates simulate operation. Cone beam computed tomography (CBCT) scans skulls acquired preoperatively generate virtual models. plans made based on cephalometric analyses, osteotomies then performed virtually. Cylinder-shaped markers placed permit correct...
In this study, the uptake characteristics of [18F]fibroblast activation protein inhibitor (FAPI) molecular imaging probe were investigated in acute radiation pneumonia and lung cancer xenografted mice before after to assess future applicability [18F]FAPI positron emission tomography/computed tomography (PET/CT) early radiotherapy response. Initially, biodistribution tracer vivo studied healthy at each time-point. A comparison [18F]fluorodeoxyglucose (FDG) PET/CT efficacy normal ICR, LLC...
Dear Editor, Small cell lung cancer (SCLC) is a low-survival malignant with mainly extensive stage (ES).1, 2 A major challenge in treating SCLC chemotherapy resistance.3 However, studies on disease evolution and molecular mechanisms of resistance during are insufficient. Here, we conducted multicentre, observational study to profile the multi-omics characteristics tumour tissue, circulating (CTC) DNA (ctDNA) Chinese ES-SCLC patients. This enrolled 54 patients, including naïve cohort relapsed...
3101 Background: IDO is an enzyme of interest in immuno-oncology because the immunosuppressive effects that result from its role tryptophan catabolism. Clinical trials inhibitors with immunotherapy are under active investigation. The addition angiogenesis inhibitor may further enhance anti-tumor immune responses. Here we report safety and efficacy results SHR9146 (IDO inhibitor) plus camrelizumab (PD-1 antibody) with/without apatinib (VEGFR-2 patients (pts) advanced solid cancers who failed...