A5051804322- Advanced Radiotherapy Techniques
- Pancreatic and Hepatic Oncology Research
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Colorectal and Anal Carcinomas
- Endometrial and Cervical Cancer Treatments
- Medical Imaging Techniques and Applications
- Advances in Oncology and Radiotherapy
- Cancer Genomics and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Sarcoma Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Glioma Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Neuroendocrine Tumor Research Advances
- Gallbladder and Bile Duct Disorders
- Microbial Inactivation Methods
- Colorectal Cancer Surgical Treatments
- Radiation Dose and Imaging
- Gastric Cancer Management and Outcomes
- Renal cell carcinoma treatment
- Management of metastatic bone disease
Azienda USL di Bologna
2021-2025
University of Bologna
2012-2024
Policlinico S.Orsola-Malpighi
2012-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2023
March of Dimes
2018
Ospedale Bellaria
2017-2018
University Medical Center Freiburg
2018
University of Freiburg
2018
Università Cattolica del Sacro Cuore
2016
Background A CE- and FDA-approved cloud-based Deep learning (DL)-tool for automatic organs at risk (OARs) clinical target volumes segmentation on computer tomography images is available. Before its implementation in the practice, an independent external validation was conducted. Methods At least a senior two training Radiation Oncologists (ROs) manually contoured of interest (VOIs) 6 tumoral sites. The auto-segmented contours were retrieved from DL-tool and, if needed, corrected by ROs....
Aim: The purpose of the present multicentric study was to review stereotactic body radiotherapy (SBRT) with or without chemotherapy (CHT) experience in locally advanced pancreatic cancer (LAPC). Endpoints were overall survival (OS), local control (LC), and distant metastasis-free (DMFS). Several parameters9 impact on these outcomes assessed. Materials Methods: Fifty-six patients LAPC undergoing SBRT+/-CHT included. SBRT median BED<sub>α/β10Gy</sub> 48.0 Gy (range=28.0-78.7). Survival curves...
Patients (pts) affected with locally advanced rectal cancer (LARC) may respond differently to neoadjuvant chemoradiotherapy (nCRT). The identification of reliable biomarkers able predict oncological outcomes could help in the development risk-adapted treatment strategies. It has been suggested that inflammation parameters have a role predicting tumor response nCRT and survival cancer, but no definitive conclusion can be drawn at present. aim current study is evaluate baseline inflammatory...
Locally advanced cervical cancer represents a significant treatment challenge. Body composition parameters such as body mass index, sarcopenia, and sarcopenic obesity, defined by sarcopenia BMI ≥ 30 kg/m
Systemic inflammation indices were found to be correlated with therapeutic outcome in several cancers. This study retrospectively analyzes the predictive role of a broad range systemic inflammatory markers patients locally advanced cervical cancer (LACC) including patient-, tumor-, and treatment-related potential prognostic factors. All underwent definitive chemoradiation pretreatment values (neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio, monocyte/lymphocyte immune index...
Background/Objective: This study aimed to assess the prognostic significance of pretreatment nutritional and systemic inflammatory indices (IIs), body composition parameters in patients with locally advanced cervical cancer (LACC) treated chemoradiation brachytherapy. The goal was identify key predictors clinical outcomes, such as local control (LC), metastasis-free survival (MFS), disease-free (DFS), overall (OS), using machine learning techniques. Materials methods: A retrospective...
Electrochemotherapy (ECT) is an attractive treatment for solid cutaneous tumours with a good response rate (55-92%). No studies have evaluated ECT performed in vulvar cancer. The aim of our study was to evaluate the safety, local tumour efficacy and relief symptoms patients affected by recurrence squamocellular cancer (V-SCC) unsuitable standard treatments.We enrolled nine histological diagnosis V-SCC. Intravenous bleomycin injected under general sedation after accurate mapping all lesions...
Presurgical carbohydrate antigen 19-9 (CA19-9) level predicts overall survival (OS) in resected pancreatic adenocarcinoma (PaC). The aim of this pooled analysis was to evaluate if presurgical CA19-9 can also predict local control (LC) and distant metastasis-free (DMFS).Seven hundred patients with PaC from eight institutions who underwent surgical resection ± adjuvant treatment between 2000 2014 were analyzed. Patients divided based on four cutoffs (5, 37, 100, 353 U/ml). Weibull regression...
Aim: To report the outcome of hypofractionated radiotherapy after radical prostatectomy (RP) for prostate cancer (PCa) using simultaneous integrated boost-intensity modulated radiation therapy (SIB-IMRT). Patients and Methods: A total 124 patients with PCa at high risk relapse RP or diagnosis biochemical were included. received 62.5 Gy to bed 45 pelvic nodes in 25 fractions. Androgen-suppressive was prescribed based on National Comprehensive Cancer Network categories. Results: Median...