A5101507500- Ferroptosis and cancer prognosis
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- VLSI and FPGA Design Techniques
- Aortic aneurysm repair treatments
- Bone Metabolism and Diseases
- Mental Health Treatment and Access
- Turtle Biology and Conservation
- Complexity and Algorithms in Graphs
- Fluid Dynamics and Vibration Analysis
- Vascular Malformations Diagnosis and Treatment
- Medical Education and Admissions
- Fluid Dynamics and Turbulent Flows
- Vestibular and auditory disorders
- Circular RNAs in diseases
- Physiological and biochemical adaptations
- Brain Metastases and Treatment
- Model Reduction and Neural Networks
- Process Optimization and Integration
- Bone and Dental Protein Studies
- Amphibian and Reptile Biology
- Photodynamic Therapy Research Studies
- Advanced Biosensing Techniques and Applications
- Advanced Graph Theory Research
- Obstructive Sleep Apnea Research
Xinjiang Agricultural University
2025
Capital Medical University
2025
Qingdao University
2021-2024
Affiliated Hospital of Qingdao University
2021-2024
J.M. Burgerscentrum
2023-2024
Delft University of Technology
2021-2024
Frederick National Laboratory for Cancer Research
2017-2022
Leidos (United States)
2017-2018
Leidos Biomedical Research Inc. (United States)
2018
National Institutes of Health
2017
Lizards are ideal models for investigating animal adaptations to climate change, given their sensitivity temperature and significance in physiological ecology. In this study, the effects of on thermal biology locomotor performance two sympatric desert lizards, Eremias roborowskii Phrynocephalus axillaris, were examined. We analyzed morphological differences, relationship between environmental temperatures (Te) selected body (Tsel), across varying Te. also assessed critical maximum (CTmax)...
To analyze the clinical characteristics of elderly patients with benign paroxysmal positional vertigo (BPPV), to provide a basis for accurate diagnosis BPPV patients. A retrospective case-control study was conducted evaluate data 12,282 diagnosed who received treatment at Vertigo Clinical Diagnosis and Treatment Research Center Beijing Tiantan Hospital, affiliated Capital Medical University, between January 2020 June 2024. Patients were categorized into an group (≥65 years old)...
Abstract Purpose Intraventricular blood flow dynamics are associated with cardiac function. Accurate, noninvasive, and easy assessments of hemodynamic quantities (such as velocity, vortex, pressure) could be an important addition to the clinical diagnosis treatment heart diseases. However, complex time-varying brings many challenges existing noninvasive image-based assessments. The development reliable techniques analysis tools is essential for application biomarkers in practice. Methods In...
Abstract Introduction Wall shear stress (WSS) is associated with the growth and rupture of an intracranial aneurysm. To reveal their underlying connections, many image-based computational fluid dynamics (CFD) studies have been conducted. However, methodological validations using both in vivo medical imaging vitro optical flow measurements were rarely accompanied such studies. Methods In present study, we performed a comparative assessment on hemodynamics patient-specific saccular aneurysm 4D...
Background The prevalence of depression among university and college students in China is nearly one-quarter. This study aimed to investigate the knowledge, attitudes practices (KAP) medical toward management. Depression, a significant public health issue, has substantial impact on students, with reported 23.8% China. Methods web-based cross-sectional was conducted between January 2023 October at three universities A self-administered questionnaire collected demographic information assessed...
Abstract Pacific Biosciences’ (PacBio) RS II sequencer, utilizing Single-Molecule, Real-Time (SMRT) technology, has revolutionized next-generation sequencing by providing an accurate long-read platform. PacBio single-molecule long reads have been used to delineate complex spliceoforms, detect mutations in highly homologous sequences, identify mRNA chimeras and chromosomal translocations, accurately haplotype phasing over multiple kilobase distances aid assembly of genomes with structural...
Development of novel monoclonal antibodies, vaccines and oncolytic virus therapies have relied on analysis biomarkers as potential predictors success.One well studied biomarker is the CD16/ FcγRIIIa receptor residue 158 F/V.Identifying variants through genotyping locus widely practiced highly varied with commonly used methods including: Sanger sequencing, flow-cytometry, PCR/RFLP, Goldengate (replaced by Infinium) TaqMAN analysis.While each these considerable backing in publications related...
Incidence of breast cancer brain metastasis is increasing. Prognosis patients with metastases extremely poor. One the major impediments in treating presence a blood-brain/tumor barrier that limits permeability chemotherapeutic drugs into parenchyma. Blood-tumor (BTB) has been shown to be heterogenous, and only at highly permeable lesions do reach tumor cells. To explore molecular differences between poorly BTBs, gene profiling was done on laser microdissected tissues from mice bearing...
Breast cancer brain metastases are incurable. The blood-brain barrier (BBB) is a multicellular dynamic structure regulating exchanges between the blood and central nervous system. As cells colonize brain, BBB evolves into blood-tumor (BTB) remains potent to compound penetration, contributing poor efficacy of CNS chemotherapy. Identifying molecular underpinnings BBB/BTB permeability will lead development efficacious treatments. Three mouse models metastasis breast (BMBC) were developed:...
Abstract Urothelial cell carcinoma is the most common cancer of renal pelvis or ureter in humans. Due to a lack animal models, its pathogenic causes remain elusive. Here, we generated IkkαΔKsp mice lacking Ikkα specifically epithelial cells developing kidney and genitourinary tract as well tubules. The mutant developed invasive papillary urothelial carcinomas initiated from pelvis, leading hydronephrosis, animals eventually died. Depleting neutrophils antibiotic treatment slowed down...
Abstract Our previous study revealed that epidural adipose-derived stem cells (ADSCs) respond to lung cancer and are involved in forming premetastatic niches. The biological functions of ADSCs lymphoma still unclear. In this study, we first confirmed the B cell lymphoma-promoting effects ADSC exosomes then compared differentially expressed genes before after exosome treatment. exosome-treated cells, S100A4 expression was much higher than cultured alone. levels had a direct relationship with...