A5100390618- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- Atmospheric chemistry and aerosols
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Atmospheric Ozone and Climate
- Air Quality and Health Impacts
- Radiomics and Machine Learning in Medical Imaging
- Renal and related cancers
- Prostate Cancer Diagnosis and Treatment
- Nutritional Studies and Diet
- Air Quality Monitoring and Forecasting
- Mobile Health and mHealth Applications
- Cardiac Imaging and Diagnostics
- Health Literacy and Information Accessibility
- Advanced MRI Techniques and Applications
- Pancreatic and Hepatic Oncology Research
- Cancer, Lipids, and Metabolism
- Sodium Intake and Health
- Bladder and Urothelial Cancer Treatments
- Liver Disease Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Diet and metabolism studies
Inner Mongolia Medical University
2016-2025
Shanxi Agricultural University
2025
Peking University
2010-2025
Second Xiangya Hospital of Central South University
2023-2025
Central South University
2023-2025
University of Science and Technology of China
2024-2025
Beijing Luhe Hospital Affiliated to Capital Medical University
2025
Peking University Third Hospital
2007-2024
Mongolian National University of Medical Sciences
2019-2024
East China Normal University
2009-2024
Single-nucleotide polymorphisms (SNP) associated with polygenetic disorders, such as breast cancer (BC), can create, destroy, or modify microRNA (miRNA) binding sites; however, the extent to which SNPs interfere miRNA gene regulation and affect susceptibility remains largely unknown. We hypothesize that disruption of target by is a widespread mechanism relevant susceptibility. To test this, we analyzed known be BC risk, in silico vitro, for their ability sites referred these SNPs. identified...
Abstract. Volatile organic compounds (VOCs) play important roles in the tropospheric atmosphere. In this study, VOCs were measured at an urban site Guangzhou, one of megacities Pearl River Delta (PRD), using a gas chromatograph–mass spectrometer/flame ionization detection (GC–MS/FID) and proton transfer reaction time-of-flight mass spectrometer (PTR-ToF-MS). Diurnal profile analyses show that stronger chemical removal by OH radicals for more reactive hydrocarbons occurs during daytime, which...
Abstract. The atmospheric processes under polluted environments involving interactions of anthropogenic pollutants and natural emissions lead to the formation various complex secondary products. Therefore, characterization oxygenated organic compounds in urban areas remains a pivotal issue our understanding evolution carbon. Here, we describe measurements an iodide chemical ionization time-of-flight mass spectrometer installed with Filter Inlet for Gases AEROsols (FIGAERO-I-CIMS) both gas...
Abstract. Ambient nitrate has been of increasing concern in PM2.5, while there are still large uncertainties quantifying the formation aerosol. The pathways aerosol at an urban site and a suburban Pearl River Delta (PRD) investigated using observation-constrained box model. Throughout campaigns, pollution episodes were constantly accompanied with increase concentrations fractions both sites. simulations demonstrate that chemical reactions daytime night contributed significantly to boundary...
Abstract. Volatile organic compounds (VOCs) are key precursors of ozone and particulate matter, which the two dominant air pollutants in urban environments. However, compositions sources VOCs aloft have rarely been reported so far. To address this highly time-resolved measurements were made by a proton-transfer-reaction time-of-flight mass spectrometer (PTR-ToF-MS) at 450 m platform on Canton Tower Guangzhou, China. A combination situ modeling techniques was used to characterize variations...
To determine the annual incidence and clinically relevant risk factors for foot ulceration in a large cohort study of diabetic ulcer (DFU) patients diabetes mellitus (DM) China. investigate 1,333 comprising 452 DFU 881 DM patients, who underwent screening, physical examination, laboratory tests eight hospitals. The were assessed at baseline terms their demographic information, medical social history, peripheral neuropathy disease (PND) periphery artery (PAD) assessment nutritional status,...
<h3>Objective</h3> MicroRNA (miRNA) expression profile can be used as prognostic marker for human cancers. We aim to explore the significance of miRNAs in colorectal cancer (CRC) metastasis. <h3>Design</h3> performed miRNA microarrays using primary CRC tissues from patients with and without metastasis, validated selected candidates 85 samples by quantitative real-time PCR (qRT-PCR). tested metastatic activity identified targets prediction algorithms, qRT-PCR, western blot luciferase assays....
We identified sunitinib alternative schedules that maintained dose intensity while decreasing adverse events in patients with metastatic renal cell cancer. also determined the impact of on clinical outcomes.We retrospectively reviewed records 18 years old or older clear cancer who received first line between January 26, 2006 and March 1, 2011 at our major comprehensive center. A subset was switched intolerable event from traditional schedule 28 days 14 off to a 7 other schedules. control...
Purpose: To investigate relationships among physical activity, changes in function, and health-related quality of life (HRQOL) patients with pancreatic adenocarcinoma enrolled a home-based exercise prehabilitation program. Methods: Patients resectable receiving preoperative chemotherapy and/or chemoradiation were on this prospective, single-arm trial advised to perform ≥60 minutes each moderate-intensity aerobic strengthening weekly. Activity was measured via self-report accelerometers,...
Intestinal farnesoid X receptor (FXR) signaling is involved in the development of obesity, fatty liver disease, and type 2 diabetes. However, role intestinal FXR atherosclerosis its potential as a target for clinical treatment have not been explored. The serum levels fibroblast growth factor 19 (FGF19), which encoded by an gene, were much higher patients with hypercholesterolemia than control subjects positively related to circulating ceramide levels, indicating link between FXR, metabolism,...
Abstract. Higher alkanes are a major class of intermediate-volatility organic compounds (IVOCs), which have been proposed to be important precursors secondary aerosols (SOA) in the atmosphere. Accurate estimation SOA from higher and their oxidation processes atmosphere is limited, partially due difficulty measurement. High-time-resolution (10 s) measurements were performed using NO+ chemical ionization proton transfer reaction time-of-flight mass spectrometry (NO+ PTR-ToF-MS) at an urban...
Abstract A previously healthy 18-year-old man with a 9-month history of upper abdominal pain and significant weight loss underwent gastroscopy, revealing an ulcerative lesion in the duodenal bulb. Enrolled clinical trial, both 18 F-FDG 68 Ga-FAPI-04 PET/CT demonstrated similar metabolic activity, though offered superior delineation. Pathology confirmed synovial sarcoma. This case highlights potential utility as radiopharmaceutical for evaluating rare gastrointestinal sarcomas.
A metal nanoparticle system has been prepared by 200 Kev Ag+ ion implantation into perfect single crystal SiO2 at room temperature to dose: 6.7×1016/cm2. The presents quasidual-layer structure: the shallower implanted layer containing noninteracting small Ag nanoparticles and deeper interacting large nanoparticles, in which great red shift, about 1 eV, comparing with plasmon resonance frequency of nanoparticle, can be clearly observed. shift is attributed multipoles interaction among high...
Abstract Purpose: Several lines of evidence suggest that diet and weight gain may be important environmental factors implicated in prostate carcinogenesis, especially tumor progression. The purpose this study was to evaluate obesity at different ages a well-characterized cohort cancer patients treated with prostatectomy develop prognostic model incorporates body mass index (BMI) as measure obesity. Experimental Design: We carried out prospective 526 registered the M.D. Anderson Cancer Center...
The current study was conducted to determine the clinical characteristics and prognostic features associated with prostatic small cell carcinoma (SCC).Between January 1985 May 2005, 83 patients SCC of prostate were identified. Univariate multivariate Cox proportional hazards modeling used assess significance parameters disease-specific outcomes.Twenty-one had no evidence distant metastasis at time diagnosis SCC, remaining demonstrating radiologic or biopsy-proven metastatic disease. Compared...
Abstract Purpose: Early events in colorectal tumorigenesis include mutation of the adenomatous polyposis coli (APC) gene and epigenetic hypermethylation with transcriptional silencing O6-methylguanine DNA methyltransferase (MGMT), human mut L homologue 1 (hMLH1), P16/CDKN2A genes. Epigenetic alterations affect genetic events: Loss MGMT via reportedly predisposes to guanine-to-adenine or cytosine-to-thymine (G:C→A:T) transition mutations KRAS P53, hMLH1 leads high levels microsatellite...