- Phytochemicals and Antioxidant Activities
- Fermentation and Sensory Analysis
- Biochemical Analysis and Sensing Techniques
- Sepsis Diagnosis and Treatment
- Gut microbiota and health
- Essential Oils and Antimicrobial Activity
- Postharvest Quality and Shelf Life Management
- Cancer therapeutics and mechanisms
- Complementary and Alternative Medicine Studies
- Pharmacogenetics and Drug Metabolism
- Adipose Tissue and Metabolism
- Food Quality and Safety Studies
- Pharmacological Effects of Natural Compounds
- Drug Transport and Resistance Mechanisms
- Horticultural and Viticultural Research
- Ginger and Zingiberaceae research
- Analytical Chemistry and Chromatography
- Chemical and Physical Properties in Aqueous Solutions
- Plant biochemistry and biosynthesis
- Drug-Induced Hepatotoxicity and Protection
- Metabolomics and Mass Spectrometry Studies
- Pomegranate: compositions and health benefits
- Thermal Regulation in Medicine
- Probiotics and Fermented Foods
- Adipokines, Inflammation, and Metabolic Diseases
Citrus Research Institute
2009-2024
First Affiliated Hospital of Heilongjiang University of Chinese Medicine
2024
Previous research has suggested that Xuebijing injection (XBJ), an herbal-based intravenous preparation, may reduce mortality among patients with sepsis.
In this study, Ougan juice (OJ) and lactic acid bacteria fermented (FOJ) were investigated individually for their capability of preventing obesity in high-fat diet (HFD)-fed C57BL/6J mice. After being administered with OJ or FOJ 10 weeks, the body weight gain, hyperlipidemia, gut microbiota dysbiosis HFD-fed mice examined. The results showed that supplementation inhibited lowered fat accumulation, reduced liver steatosis, improved glucose homeostasis insulin sensitivity, increased brown...
In this work, we employed a global untargeted metabolomics technique to explore the intricate composition of anthocyanin constituents in bayberry wine and elucidate their alteration during maceration process. Our analysis uncovered 20 distinct forms anthocyanins wine, including cyanidin-type, delphinidin-type, peonidin-type, malvidin-type, other-type. 'Dongkui' (DK) was characterized by predominance glycoside cyanidin-type delphinidin-type anthocyanins, while 'Shuijing' (SJ) mainly contained...
Citrus seed waste material provides a new solution for addressing the shortage of edible oils in China. supercritical CO2 fluid extraction (SFE), sub-critical butane (SCE), cold press (CP), soxhlet (SXE), and ultrasonic-assisted (UAE) were preformed to obtain Ougan (Citrus reticulata cv. Suavissima) oil. tested physicochemical properties, fatty acid composition, limonoids, polyphenols, total carotenoids, tocopherols, vitro antioxidant activities. The results indicated that SCE oil has most...
This study examined the effects of phase II metabolism and efflux transportation on bioavailability naringin, hesperidin, their aglycones (naringenin hesperetin) in rats. Results indicated naringin hesperidin have a lower oral than aglycones. Of all enzymes tested, UDP-glucuronosyltransferase (UGT) 1A1, UGT1A2, UGT1A3, UGT1A7 SULT sulfotransferase (SULT) 1B1 were minor importance regarding naringenin hesperetin small intestine. Naringin, extensively metabolised liver. Naringin more...
Background Sepsis, affecting over 30 million people worldwide each year, is a key mortality risk factor in critically ill patients. There are significant regional discrepancies its impact. Acetaminophen, common over-the-counter drug, often administered to control fever suspected infection cases intensive care units (ICUs). It considered generally safe when used at therapeutic levels. Despite widespread use, there’s inconsistent research regarding efficacy sepsis management, which creates...
Grapefruit has attracted much attention as a functional fruit, of which "Cocktail" is special variety with low acidity. The present study aimed to investigate the effects alcoholic fermentation on non-volatile and volatile compounds grapefruit juice. To analyze, non-targeted metabolomics method based UPLC-MS/MS volatiles analysis using GC-IMS were performed. A total 1015 phytochemicals identified, including 296 flavonoids 145 phenolic acids, noticeably increasing varieties abundance...
Poncirin (PC) and its aglycone, isosakuranetin (IR), occur naturally in citrus fruits. This study aimed to explore the pathways behind different health benefits of PC IR by evaluating effect these two bioactive flavonoids on gut microbial diversity metabolomics mice. The 16S rRNA gene sequencing was used analyze alteration microbiota mice after intervention. metabolic impact were studied using a approach based LC-MS analysis. Results showed that, 7 days intervention, multiplied abundance...
High performance liquid chromatography (HPLC) methods have been established for simultaneously determining the 10 organic acids in fruit or soil. Two chromatographic (LC) columns with reversed phase (RP) (Titank C18) and hydrophilic interaction (HILIC) (Poroshell 120 HILIC-Z) were selected to separate molecular ionic state, respectively. Meanwhile, mobile phases had different solvents pH values two states. Results indicated that these can complement each other avoid various matrix...
Lactic acid fermentation was applied to Ougan juice (OGJ) for the first time. This study conducted improve taste of OGJ by slight lactic fermentation. separately fermented at 37°C using Lactobacillus plantarum and paracasei. Results showed that bacteria strains can utilize malic as a carbon source, without consumption sugar. The observed sugar:acid ratio highest in L. group (3.9) 6 hr, paracasei (4.5) 12 which resulted improved sensory acceptance (taste, acidity, aroma, color) OGJ. Moreover,...
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