A5087659066- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Reproductive Physiology in Livestock
- Ectopic Pregnancy Diagnosis and Management
- Reproductive Biology and Fertility
- Tendon Structure and Treatment
- Ovarian cancer diagnosis and treatment
- Periodontal Regeneration and Treatments
- Reproductive Health and Contraception
- Phytochemistry and biological activities of Ficus species
- Ovarian function and disorders
- Pregnancy and preeclampsia studies
- Reconstructive Surgery and Microvascular Techniques
- Circular RNAs in diseases
- Berberine and alkaloids research
- Uterine Myomas and Treatments
Qingdao University
2018-2024
Qingdao Women and Children's Hospital
2021-2024
Yuhuangding Hospital
2018-2021
Affiliated Hospital of Qingdao University
2019
Abstract Background Platelet‐rich plasma (PRP) contains abundant growth factors and is gradually used in the field of reproduction. A thin endometrium recognized as a critical factor embryo implantation failure. Endometrial mesenchymal stem cells (EnMSCs), which were isolated from human menstrual blood, are highly proliferative show multiple differentiation capacity. The current study was to investigate effect PRP on proliferation migration EnMSCs, effectiveness treatment patients with...
Objective To evaluate whether the intrauterine perfusion of platelet-rich plasma (PRP) before frozen-thawed embryo transfer (FET) improves pregnancy outcomes patients with repeated implantation failure (RIF). Methods This retrospective study included 288 infertile women RIF after undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment from October 1, 2019, to January 2021, at Qingdao Women and Children's Hospital. Patients were divided into two groups...
Nuclear factor E2-related 2 (NRF2) plays an anti-inflammatory role in several pathological processes, but its function lipopolysaccharide- (LPS-) induced goat endometrial epithelial cells (gEECs) is still unknown. We designed a study to investigate the of NRF2 LPS-induced gEECs. LPS was found increase expression and nuclear abundance gEECs dose-dependent manner. knockout (KO) not only increased proinflammatory cytokines (TNF-α, IL-1β, IL-6 IL-8) also TLR4, p-IκBα/IκBα, p-p65/p65 proteins....
Abstract Background Polycystic ovarian syndrome (PCOS) accounts for about 75% of anovulatory infertility. The cause PCOS is not clear. CircRNAs acting as miRNA sponges mediate the post-transcriptional regulation multiple genes. CYP19A1 a limiting enzyme in steroidogenesis pathway. However, mechanism circRNAs regulating granulosa cell (GC) estradiol secretion remains to be elucidated. Methods Bioinformatics was used predict potential target miRNAs circ_0043532 and genes miR-1270. Target mRNA...
Thin endometrium usually means abnormal endometrial receptive leading to implantation failure. Platelet-rich plasma (PRP) containing high concentrated platelets and proteins, such as various growth factors. It has been suggested that local mechanical stimulation (EMS) could recruit cytokines factors enhance encourage embryo implantation. We aimed investigate whether PRP intrauterine perfusion combined with hysteroscopic EMS affect the outcome of IVF in patients thin endometrium. 32...