A5103108435- Spectroscopy and Laser Applications
- Advanced Fiber Laser Technologies
- Radiomics and Machine Learning in Medical Imaging
- Photonic and Optical Devices
- MRI in cancer diagnosis
- COVID-19 Clinical Research Studies
- Multiple Myeloma Research and Treatments
- SARS-CoV-2 and COVID-19 Research
- Acute Myeloid Leukemia Research
- Terahertz technology and applications
- Aquaculture Nutrition and Growth
- Radiology practices and education
- Semiconductor Lasers and Optical Devices
- Covalent Organic Framework Applications
- Platelet Disorders and Treatments
- Inflammatory Bowel Disease
- Metamaterials and Metasurfaces Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Plasmonic and Surface Plasmon Research
- Innovations in Medical Education
- Advanced X-ray and CT Imaging
- Dermatological and COVID-19 studies
- Microscopic Colitis
- Advanced MRI Techniques and Applications
- COVID-19 Impact on Reproduction
Peking Union Medical College Hospital
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Chinese Academy of Sciences
2019-2024
The First Affiliated Hospital, Sun Yat-sen University
2009-2024
Sun Yat-sen University
2005-2024
Shanghai Institute of Microsystem and Information Technology
2019-2024
University of Chinese Academy of Sciences
2019-2024
Jilin University
2021-2023
ShanghaiTech University
2022
Chongqing Normal University
2022
Two-dimensional covalent-organic frameworks (2D COFs) have recently emerged as great prospects for their applications new photocatalytic platforms in solar-to-hydrogen conversion; nevertheless, inefficient solar energy capture and fast charge recombination hinder the improvement of hydrogen production performance. Herein, two photoactive three-component donor-π-acceptor (TCDA) materials were constructed using a multicomponent synthesis strategy by introducing electron-deficient triazine...
Abstract Two‐dimensional covalent organic frameworks (2D‐COFs) have emerged as attractive platforms for solar‐to‐chemical energy conversion. In this study, we implemented a gradient heating strategy to synthesize sp 2 ‐carbon‐linked triazine‐based COF, COF‐JLU100, exhibiting high crystallinity, large surface area, good durability and carrier mobility solar‐driven photocatalytic hydrogen evolution. The Pt‐doped COF‐JLU100 demonstrated evolution rate of over 100 000 μmol g −1 h water splitting...
Uncooled infrared photodetectors have evoked widespread interest in basic research and military manufacturing because of their low-cost, compact detection systems. However, existing uncooled utilize the photothermoelectric effect radiation operating at 8-12 µm, with a slow response time millisecond range. Hence, exploration new mid-wavelength (MWIR) heterostructures is conducive to development ultrafast high-performance nano-optoelectronics. This study explores van der Waals heterojunction...
A transmission type flat-panel X-ray source in diode structure was fabricated. Large-scale patterned ZnO nanowires grown on a glass substrate by thermal oxidation were utilized as field emitters, and tungsten thin film coated silica used the anode. Uniform distribution of generation achieved, which benefited from uniform electron emission nanowires. Self-ballasting effect induced intrinsic resistance nanowire decreasing screening caused emitters account for emission. Characteristic peaks W-L...
Coronavirus disease 2019 (COVID-19) can affect the haematopoietic system. Thrombocytopenia at admission was prevalent, while late-phase or delayed-phase thrombocytopenia (occurred 14 days after symptom onset) is rare. This retrospective, single-centre study screened 450 COVID-19 patients and enrolled 271 Union Hospital, Wuhan, China, from January 25 to March 9, 2020. COVID-19-associated occurred in 11·8% of enrolling patients. The prone develop elderly with low lymphocyte count on admission....
Due to its fast and high-resolution characteristics, dual-comb spectroscopy has attracted an increasing amount of interest since first demonstration. In the terahertz frequency range where abundant absorption lines (fingerprints) molecules are located, multiheterodyne that employs technique shows advantage in real-time spectral detection over traditional Fourier transform infrared or time domain spectroscopies. Here, we demonstrate compact based on quantum cascade lasers (QCLs). our...
Abstract Recently, there are growing interests in developing super‐resolution metalenses for applications of focusing and imaging. On one hand, various sub‐diffraction have been demonstrated; however, most them only work at a single wavelength or multiple discrete wavelengths. the other previously reported broadband achromatic diffraction‐limited, their focal spots larger than corresponding Abbe diffraction limit, 0.5λ/NA, where λ NA lens working numerical aperture. In present work, an...
Chromatic optical lenses have promising applications in three-dimensional imaging, which allows fast spectral tomography without mechanical moving parts. The scanning range of current chromatic is limited by their dispersion ability. recent development metasurfaces provides ideal blocks for wavefront manipulation and engineering artificial materials at sub-wavelength scales. Hyper-dispersive metalenses can be realized utilizing dispersive meta-atoms, enhanced compared to regular diffractive...
Abstract Long noncoding RNAs (lncRNAs) are known to play a key role in chronic myelocytic leukemia (CML) development, and we aimed identify the involvement of lncRNA HOX antisense intergenic RNA (HOTAIR) CML via binding DNA methyltransferase 1 (DNMT1) accelerate methylation phosphatase tensin homolog (PTEN) gene promoter. Bone marrow samples from patients normal bone healthy controls were collected. HOTAIR, DNMT1, DNMT3A, DNMT3B, PTEN expression was detected. The biological characteristics...
AIM:To investigate the correlation between microvessel density and spiral CT perfusion imaging in colorectal carcinoma. METHODS:Thirty-seven patients, with histologically proven carcinoma, underwent water enema scan.The largest axial surface of primary tumor was searched on unenhanced images.At this level, enhanced dynamic scan series acquired.Time-density curves (TDC) were created from region interest drawn over tumor, target artery by Toshiba Xpress/SX functional software.Then...
Acute myeloid leukemia (AML) is the most common type of in adults. Its therapy has not significantly improved during past four decades despite intense research efforts. New molecularly targeted therapies are great need. The proto-oncogene c-Myc (MYC) an attractive target due to its transactivation role multiple signaling cascades. Deregulation MYC considered one a series oncogenic events required for tumorigenesis. However, limited knowledge available on which mechanism underlie...
Immunotherapy is a significant risk factor for severe COVID-19 in multiple myeloma (MM) patients. Understanding how immunotherapies lead to crucial improving patient outcomes. Human protein microarrays were used examine the expression of 440 molecules MM patients treated with bispecific T-cell engagers (BiTe) (n = 9), anti-CD38 monoclonal antibodies (mAbs) 10), and proteasome inhibitor (PI)-based regimens 10). Differentially expressed proteins (DEPs) identified analyzed using bioinformatics....
Background Deep Vein Thrombosis (DVT) represents a significant complication following orthopedic injuries, particularly patellar fractures. Despite the prevalence, comprehensive studies assessing incidence rates and identifying specific risk factors in fracture patients are limited. Methods This retrospective analysis reviewed electronic medical records from 3311 treated for fractures at two tertiary hospitals between November 2013 January 2023. The study focused on patient demographics,...
Autophagy, a highly conserved cellular protein degradation process, has been involved in acute myeloid leukemia (AML). The present study aims to establish novel, autophagy-related prognostic signature for prediction of AML prognosis. Differentially expressed genes and healthy samples were screened using GSE1159. Univariate Cox regression analysis was applied determine survival-associated Cancer Genome Atlas (TCGA) cohort. Lasso performed develop multiple-gene signatures. A novel six-gene...
Cancer cells-secreted extracellular vesicles (EVs) have emerged as important mediators of intercellular communication in local and distant microenvironment. Our initial GEO database analysis identified the presence differentially-expressed microRNA-1246 (miR-1246) acute myeloid leukemia (AML) cell-derived EVs. Consequently, current study set out to investigate role AML-derived EVs-packaged miR-1246 stem cells (LSCs) bioactivities. The predicted binding between LRIG1 was verified using dual...
ABSTRACT The pandemic COVID-19 pneumonia has engulfed the entire world. Hematopoietic system can also be affected by COVID-19. Thrombocytopenia at admission was prevalent, while late-phase or delayed-phase thrombocytopenia is obscure. This retrospective single-center case series analyzed patients with Union Hospital, Wuhan, China, from January 25th to March 9th, 2020. Analysis began on 11th, associated occurred in 11.8% percent of enrolled patients. prone develop elderly low lymphocyte count...
Endometriosis is an estrogen-dependent gynecological disease primarily affecting women of childbearing age, which gives rise to pelvic pain calling for multiple operations, and sometimes leading infertility. However, the etiology endometriosis remains poorly understood. In this study we investigated roles two Ubiquitin E3 Ligases, namely hsc70-interacting protein (CHIP) mouse double minute 2 (MDM2), in abnormal estrogenic activity endometriosis. We first collected endometrial tissues from 91...
Stable operation is one of the most important requirements for a laser source high-precision applications. Many efforts have been made to improve stability lasers by employing various techniques, e.g., electrical and/or optical injection and phase locking. However, these techniques normally involve complex experimental facilities. Therefore, an easy implementation evaluation still challenging, especially emitting in terahertz (THz) frequency range because broadband photodetectors mature...
Endometriosis (EMS) is a gynecologic disorder associated with infertility and characterized by the endometrial-type mucosa outside uterine cavity. Currently available treatment modalities are limited to undesirable effects. Thus, in present study, we sought study pathogenesis mechanism of EMS. For this purpose, ectopic eutopic endometrial tissues were resected from 86 patients EMS 54 infertile without EMS, respectively. The regulatory among HES family bHLH transcription factor 5 (HES5),...
Dual-comb sources with equally spaced and low phase noise frequency lines are of great importance for high resolution spectroscopy metrology. In the terahertz range, electrically pumped semiconductor quantum cascade lasers (QCLs) suitable candidates comb dual-comb operation. For a single laser comb, repetition rate can be locked using microwave injection locking carrier to highly stable source. However, two combs, four frequencies (two rates offset frequencies) should simultaneously locked;...
Optical feedback exists in most laser configurations and strongly affects performances depending on the strength, length, phase. In this paper, we investigate frequency comb behaviour of a semiconductor quantum cascade emitting around 4.2 THz with external optical feedback. A periodic evolution inter-mode beatnote from single-line to multiple-line structures is experimentally observed minor change length (phase) wavelength scale. The stability also measured compared same without Furthermore,...
Mode-locking operation and multimode instabilities in Terahertz (THz) quantum cascade lasers (QCLs) have been intensively investigated during the last decade. These studies unveiled a rich phenomenology, owing to unique properties of these lasers, particular their ultrafast gain medium. Thanks this, QCLs modulation intracavity field intensity gives rise strong population inversion, directly affecting laser current. In this work we show that property can be used study real-time dynamics THz...