A5100646303- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Thyroid Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Nonmelanoma Skin Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Fuzzy Systems and Optimization
- Chronic Kidney Disease and Diabetes
- Ear and Head Tumors
- RNA modifications and cancer
- Radiomics and Machine Learning in Medical Imaging
- Energy Load and Power Forecasting
- Voice and Speech Disorders
- Optimization and Mathematical Programming
- Multi-Criteria Decision Making
- Infectious Diseases and Mycology
- Esophageal Cancer Research and Treatment
- Cancer-related gene regulation
- Renal and Vascular Pathologies
- Stock Market Forecasting Methods
China-Japan Friendship Hospital
2025
Beijing Tongren Hospital
2013-2024
Capital Medical University
2013-2024
Guangdong Medical College
2017-2024
Beijing Institute of Neurosurgery
2017-2023
Fuzhou University
2010-2022
China Automotive Technology and Research Center
2022
Second Military Medical University
2012-2020
Shanghai Changzheng Hospital
2020
Weatherford College
2020
With the development of blockchain and digital currencies, central banks all over world are accelerating process CBDC development. However, it is still controversial on adoption in design. In paper, we analyze both functional non-functional requirements design, make a literature review based schemes. Analysis findings show that permissioned more suitable for than permissionless blockchain. Besides, there some challenges CBDC, such as performance, scalability, cross-chain interoperability....
No prediction rule is currently available for advanced colorectal neoplasms, defined as invasive cancer, an adenoma of 10 mm or more, a villous adenoma, with high-grade dysplasia, in average-risk Chinese. In this study between 2006 and 2008, total 7,541 Chinese persons aged 40 years older who had complete colonoscopy were included. The derivation validation cohorts consisted 5,229 2,312 persons, respectively. A was developed from logistic regression model then internally externally...
In this study, a next-generation sequencing strategy on 16S ribosomal RNA (16S rRNA) gene was employed to analyze 70 oral samples from 32 patients with throat cancer, nine vocal cord polyp, and 29 healthy individuals (normal controls). Using strategy, we demonstrated, for the first time, that salivary microbiota of cancer were significantly different those polyp individuals. We observed beta diversity group divergent both normal groups, while alpha-diversity indices such as Chao1 estimator...
Background: Considerable modifications have been introduced in the new edition of American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) TNM staging system. Based National Institute's Surveillance, Epidemiology, and End Results (SEER) database, this study aimed to compare 7th 8th editions AJCC/UICC system patients with papillary thyroid microcarcinoma (PTMC) follicular variant (FVPTMC). Methods: A Data from 2004 2014 39,032 registered SEER database were...
Background Renal dysfunction leads to poor prognosis of patients with coronary artery disease (CAD). Current studies have reported the or mortality various diseases using different estimated glomerular filtrate rate (eGFR) formulas, while performance these equations is unclear in CAD patients. We aim evaluate predict effect creatinine-based eGFR (eGFRcr), cystatin C-based (eGFRcys), and both creatinine (eGFRcr-cys)
Tumor necrosis factor alpha (TNF-α) plays an important role in inflammation, immunity, and defense against infection clearance of human papillomavirus (HPV). Thus, genetic variants may modulate individual susceptibility to HPV-associated oral squamous cell carcinoma (OSCC).In this study we genotyped four common single nucleotide polymorphisms (SNPs) the TNF-α promoter [ -308G > A(rs1800629), -857C T (rs1799724), -863C A (rs1800630), -1031T C (rs1799964)] determined HPV16 serology 325 OSCC...
Irritable bowel syndrome (IBS) is a common functional disease of the gastrointestinal tract. The current study aimed to examine association between visceral hypersensitivity in IBS and cortical activation using magnetic resonance imaging (fMRI), elucidate role psychological factors pathogenesis IBS. present included 31 patients with 20 healthy controls. Cerebral function was assessed fMRI. During imaging, Sengstaken-Blakemore tube placed within rectum approximately 10 cm from anus, following...
To investigate factors that contribute to lymph node metastasis (LNM) from clinical cT2-T4 N0M0 (cN0) supraglottic laryngeal carcinoma (SLC), and predict the risk of occult before surgery.A total 121 patients who received surgery were retrospectively analyzed. Relevant regarding cervical LNM Multivariate analyses conducted region where occurred prognosis.The overall metastatic rate cN0 SLC was 28.1%. Metastatic rates 15.4%, 32.5% 35.7% for T2, T3 T4, respectively. levels II, III IV 19.6%,...
// Ping Chen 1, * , Wenbin Yu 2, Junwei Huang 1 Hongbo Xu Guojun Li 3, 4 Xiaohong Zhigang Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China 2 Key Laboratory Carcinogenesis Translational Research (Ministry Education/Beijing), surgery, Peking University Cancer Hospital & Institute, Houston, TX 77030, USA 3 Epidemiology, The Texas M. D. Anderson Center, These authors contributed equally to this work co-first...
Purpose: TGFβ1 plays a critical role in inflammation and immune responses treatment response survival. variants may affect its expression level or functional efficiency, thus modifying tumor status survival human papillomavirus (HPV)-positive squamous cell carcinoma of the oropharynx (SCCOP).Experimental Design: We determined HPV16 genotyped three polymorphisms 564 incident SCCOP patients treated with radiotherapy chemoradiation. Univariate multivariable Cox models were used to evaluate...
Cervical lymph node metastatic rates tend to increase by T stage in cN0 glottic laryngeal carcinoma (GLC). Moreover, cervical metastasis (LNM) shows a sequential pattern according the regions involved and LNM affects prognosis.To investigate factors that contribute of N0 (cN0) T2-T4 GLC their effect on prognosis.A total 212 patients who had been admitted between December 2002 January 2013 were retrospectively analyzed. They included 202 men 10 women, median age 58.6 years (range 29-85...
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. The five-year survival rate of HNSCC has not improved even with major technological advancements in surgery chemotherapy. Currently, docetaxel, cisplatin, 5-fluoruracil (TPF) treatment been popular chemotherapy method for HNSCC; but only a small percentage patients exhibit good response to TPF treatment. Unfortunately, at present, no reasonably effective prediction model exists assist clinicians patient...
Although the role of T cells in tumor immunity and modulation microenvironment (TME) has been extensively studied, their precise involvement gastric adenocarcinoma remains inadequately explored. In this work, we analyzed single-cell RNA sequencing data set GSE183904 identified 322 cell marker genes using "FindAllMarkers" method R package "Seurat". STAD patients TCGA database were divided into high-risk low-risk categories based on risk scores. The five-gene prediction signature can predict...
This study aimed to establish a model for predicting the three-year survival status of patients with hypopharyngeal squamous cell carcinoma using artificial intelligence algorithms.Data from 295 were analysed retrospectively. Training sets comprised 70 per cent data and test remaining 30 cent. A total 22 clinical parameters included as training features. In total, 12 different types machine learning algorithms used construction. Accuracy, sensitivity, specificity, area under receiver...
Polymorphisms of the XPC gene have been reported to be associated with an increased risk head and neck cancer (HNC), though exact biological effect is still unclear. Genetic association studies (GAS) investigating associations between three common polymorphisms (PAT, Lys939Gln, Ala499Val) HNC produced contradictory inconclusive results. The aim this meta-analysis evaluate contributions these HNC. A literature search was conducted in PubMed, Embase, Web Science, Cochrane Library, China...
Abstract Background We performed a paired analysis to compare the therapeutic effect between induction chemotherapy‐based organ‐preservation approach and immediate total laryngectomy in hypopharyngeal squamous cell carcinoma patients requiring laryngectomy. Methods 351 who were treated with compared 110 The main measures outcomes progression‐free survival (PFS), overall (OS), larynx function preservation (LFPS). Results No statistical difference was observed for 3‐, 5‐, 10‐year PFS OS two...
Infective endocarditis is a bacterial or fungal infection of the heart valves endocardial surface, and it frequently forms vegetation can lead to systemic embolism. Dislodged rarely results in coronary artery embolism (CAE) subsequent acute myocardial infarction. A 43-year-old male patient was emergently brought our hospital for suspected Coronary angiography performed showed left circumflex artery. Thrombus aspiration during angiography. Echocardiography formation posterior leaflet mitral...
Objective: To study the significance of induction chemotherapy and subsequent comprehensive therapy for overall survival rate (OS) larynx dysfunction-free (LDFS) in patients with advanced hypopharyngeal carcinoma. Methods: Patients who met inclusion criteria diagnoses carcinoma between 2011 2017 received 2 or 3 cycles TPF regimen chemotherapy. attained complete response (CR) radical partial (PR) reduction tumor volume was more than 70% were defined as large PR concurrent chemoradiotherapy....
Abstract The aim of this study was to compare the outcomes laparoscopic surgery (LAP) and open gastric (OP) in early cancer patients aged ≥70 years.We conducted a retrospectively analysis among patientswith pathological T 1 N 0 M cancer,who underwent LAP or OP between January 1, 2001 December 31, 2008. We identified well-balanced cohort 2,360 (1180 each group). has been shown offer superior perioperative results OP, including lower blood loss, shorter time oral intake, walk bowel function...
The lack of standardized treatment is problematic in laser surgery for laryngeal cancer, and may result an increased recurrence rate. This study analyzed the prognosis early carcinoma after different types cordectomy with surgery.A cohort 818 patients stage Tis or T1 primary glottic squamous cell treated CO2 was retrospectively analyzed.Of patients, According to Kaplan-Meier method, rate 5-year overall survival 92.8%, rates disease-specific locoregional control were 96.9% 91.3%,...
Objective: To study the clinical characteristics of mucosal melanoma in head and neck, including risk factors affecting distant metastasis, recurrence survival rate, to provide basis for individualized treatment neck. Methods: The data 117 cases neck treated from January 2004 June 2016 Beijing Tongren Hospital were analyzed retrospectively, prognosis, metastasis local analyzed.Kaplan-Meier analysis was used analysis, Log-Rank test comparison between groups. Results: follow-up time 5-139...