A5100342519- Aortic Disease and Treatment Approaches
- Cancer Immunotherapy and Biomarkers
- Nanocluster Synthesis and Applications
- Aortic aneurysm repair treatments
- Metal-Organic Frameworks: Synthesis and Applications
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Reproductive Biology and Fertility
- Cardiac Valve Diseases and Treatments
- Hair Growth and Disorders
- Covalent Organic Framework Applications
- Circular RNAs in diseases
- Extracellular vesicles in disease
- Viral gastroenteritis research and epidemiology
- Cancer Genomics and Diagnostics
- Liver Disease Diagnosis and Treatment
- Ovarian function and disorders
- Signaling Pathways in Disease
- Dermatologic Treatments and Research
- Cancer-related Molecular Pathways
- Cancer Cells and Metastasis
- Peptidase Inhibition and Analysis
- Gastrointestinal Tumor Research and Treatment
- Infectious Aortic and Vascular Conditions
- Inflammatory Biomarkers in Disease Prognosis
Guiyang Medical University
2019-2025
Zhengzhou University
2018-2025
Third Affiliated Hospital of Sun Yat-sen University
2018-2025
Capital Medical University
2009-2025
Affiliated Hospital of Guizhou Medical University
2021-2025
Beijing Anzhen Hospital
2016-2025
Sun Yat-sen University
2018-2025
Third Affiliated Hospital of Zhengzhou University
2025
Southwest Medical University
2025
Second People’s Hospital of Yibin
2025
High-quality InP-based quantum dots (QDs) have become very promising, environmentally benign light emitters for display applications, but their synthesis generally entails hazardous hydrofluoric acid. Here, we present a highly facile route to InP/ZnSe/ZnS core/shell/shell QDs with near-unity photoluminescence yield. As the key additive, inorganic salt ZnF2 mildly reacts carboxylic acid at high temperature and in situ generates HF, which eliminates surface oxide impurities, thus facilitating...
The sensitivity of conventional thin-film OFET-based sensors is limited by the diffusion analytes through bulk films and remains central challenge in sensing technology. Now, for first time, an ultrasensitive (sub-ppb level) sensor reported that exploits n-type monolayer molecular crystals (MMCs) with porous two-dimensional structures. Thanks to crystal structure NDI3HU-DTYM2 (NDI) controlled formation structure, a world-record detection limit NH3 (0.1 ppb) was achieved. Moreover, MMC-OFETs...
A four-year-old boy developed recurrent fever and severe pneumonia in April, 2022. High-throughput sequencing revealed a reassortant avian influenza A-H3N8 virus (A/Henan/ZMD-22-2/2022(H3N8) with avian-origin HA NA genes. The six internal genes were acquired from Eurasian lineage H9N2 viruses. Molecular substitutions analysis the haemagglutin retained avian-like receptor binding specificity but that PB2 possessed sequence changes (E627K) associated increased virulence transmissibility...
Stable stimulus-responsive materials are highly desirable due to their widespread potential applications and growing demand in recent decades. Despite the fact that viologen derivatives have long been known as excellent photochromic electrochromic materials, development of stable viologen-based multifunctional smart with short coloration times remains an exciting topic. To obtain dual responsive embedding ligand into a robust metal oxide cluster increase its stability sensitivity is...
Abstract Background and Aims Stanford type A aortic dissection (AD) is a degenerative remodelling disease marked by an exceedingly high mortality without effective pharmacologic therapies. Smooth muscle cells (SMCs) lining tunica media adopt range of states, their transformation from contractile to synthetic phenotypes fundamentally triggers AD. However, the underlying pathomechanisms governing this population shift subsequent AD, particularly at distinct temporal stages, remain elusive....
Atom-precise metal nanoclusters (NCs) with large bulk (nuclearity >60) are important species for insight into the embryonic phase of nanoparticles and their top-down etching synthesis. Herein, we report a metastable rod-shaped 70-nuclei copper-hydride NC, [Cl@Cu
Abstract Many sophisticated chemical and physical properties of porous materials strongly rely on the presence metal ions within structures. Whereas homogeneous distribution metals is conveniently realized in metal–organic frameworks (MOFs), limited stability potentially restricts their practical implementation. From that perspective, development metal–covalent organic (MCOFs) may address these shortcomings by incorporating active species atop highly stable COF backbones. This Minireview...
The key pathophysiological changes in androgenetic alopecia (AGA) are limited to hair follicles (HFs) frontal and vertex regions, sparing the occipital region.To identify biological differences among HF subpopulations.Paired HFs from 10 male donors with AGA were collected for RNA sequencing assay. Furthermore, cell experiments conducted on identified genes reveal their roles AGA.Transcriptome profiles revealed that 506 mRNAs, 55 microRNAs 127 long noncoding RNAs differentially expressed HFs....
Checkpoint immunotherapy is capable of unleashing T cells for controlling tumor, whereas it destroyed by immunosuppressive myeloid cell.Apoprotein E (APOE) refers to a ligand in terms the members low-density lipoprotein (LDL) receptor family mediating Apoprotein B-involving atherogenic clearance.Besides, tumor-infiltration macrophage can express APOE.The present study reported Apoe -/-mice exhibit higher resistance toward development three types carcinomas as compared with mice wild type and...
Abstract High-intensity Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is a recent, non-invasive line of treatment for medication-resistant tremor. We used MRgFUS to produce small lesions in the thalamic ventral intermediate nucleus (VIM), an important node cerebello-thalamo-cortical tremor network, 13 patients with tremor-dominant Parkinson’s disease or essential Significant alleviation target hand ensued ( t (12) = 7.21, p < 0.001, two-tailed), which was strongly associated...
Abstract Chiral imidodiphosphates (IDPs) have emerged as strong Brønsted acid catalysts for many enantioselective processes. However, the dynamic transformation between O,O ‐ syn and anti conformers typically results in low enantioselectivity. Here we demonstrate that topologies of metal‐organic frameworks (MOFs) can be exploited to control IDP conformations local chiral microenvironments catalysis. Two porous Dy‐MOFs with different are obtained from an enantiopure 1,1′‐biphenol IDP‐based...
Although alterations in the expressions of protein kinase C (PKC) have been implicated breast carcinogenesis, roles specific isoforms this process remain elusive. In present study, we examined PKCbeta1 and beta2 growth control human cancer cell lines. The PKCbeta-specific inhibitor LY379196 significantly inhibited lines MCF-7, MDA-MB-231, BT474, but not normal mammary epithelial line MCF-10F. Treatment MCF-7 cells with caused an increase fraction G(1) phase cycle. To explore beta2, used cDNA...
The formation of an effective vascular network can promote peripheral angiogenesis, ensuring supply blood, oxygen, and nutrients to engineered bladder, which is important for bladder tissue engineering. Stromal fraction cells (SVFs) vascularization improve the function injured tissues. In this study, adipose tissue-derived SVFs were introduced as angiogenic cell source seeded into acellular matrix (BAM) generate a SVF-BAM complex reconstruction. morphological regeneration functional...
A novel high-nuclearity silver chalcogenolate nanocluster [Ag<sub>50</sub>S<sub>7</sub>(SPhF)<sub>36</sub>(dppp)<sub>6</sub>] have been obtained, which shows reversible color changes in response to temperature and pressure.
Abstract To evaluate the feasibility and efficacy of diffusion tensor imaging (DTI) for detecting early brain microstructure alterations in germinal matrix-intraventricular hemorrhage (GMH-IVH) rat model. This study used a postnatal day 5 (PND 5) model GMH-IVH. T2-weighted DTI were performed during acute (6 h 24 h) subacute (3d 7d) phases after Four parameters including fractional anisotropy (FA), mean (MD), axial (AD) radial (RD) collected 9 specific regions to assess alterations. Early...
ABSTRACT A facile, general, and highly efficient one‐pot approach to obtain azobenzene (azo)‐containing molecularly imprinted polymer (MIP) nanoparticles with photoresponsive template binding release properties in aqueous media is described, which involves the combined use of hydrophilic macromolecular chain transfer agent‐mediated reversible addition‐fragmentation precipitation polymerization easily available water‐insoluble azo functional monomers. The resulting azo‐containing MIPs were...