A5078967302- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Urticaria and Related Conditions
- Cancer Immunotherapy and Biomarkers
- Nonmelanoma Skin Cancer Studies
- Epigenetics and DNA Methylation
- Cancer and Skin Lesions
- Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Platelet Disorders and Treatments
- CAR-T cell therapy research
- Urological Disorders and Treatments
- Drug-Induced Adverse Reactions
- Drug-Induced Ocular Toxicity
- Cutaneous lymphoproliferative disorders research
- Oral and gingival health research
- Molecular Biology Techniques and Applications
- Urologic and reproductive health conditions
- Infectious Diseases and Mycology
- Genital Health and Disease
- Contact Dermatitis and Allergies
Hospital del Mar Research Institute
2015-2022
Universitat Pompeu Fabra
2022
Universitat Autònoma de Barcelona
2019-2022
Parc de Salut
2015-2019
Hospital Del Mar
2013-2018
Municipal Institute for Medical Research
2018
Dipeptidyl peptidase-4 (DPP-4) inhibitors have increasingly been identified as causative agents of bullous pemphigoid. The clinical and immunological characteristics this pemphigoid variant are still unclear. objective our study was to analyze the features patients with induced by DPP-4 inhibitors.All diagnosed inhibitor-associated at dermatology departments in three Spanish centers during period 2013 2015 were included. ELISA assays for NC16A domain BP180 BP230 performed. Immunoblot studies...
Abstract: Programmed cell death ligand 1 (PD-L1) expression by tumor cells plays an important role in the inhibition of T cell–mediated immune response cancer. PD-L1 has been linked to poor prognosis a wide variety cancers. However, cutaneous squamous carcinoma (cSCC) scarcely studied, and its as biomarker remains controversial. The association metastatic risk series cSCC was assessed. CD8 immunostainings full excision sections 99 primary tumors 24 lymphatic metastases were...
Abstract Although most cutaneous squamous cell carcinomas (cSCCs) develop from actinic keratoses (AKs), the key events in this evolution remain unclear. We have combined results of different genomic and expression array platforms on matched concomitant samples sun‐exposed skin (SES), AK, cSCC 10 immunocompetent patients. Gene analysis copy number alterations were assessed using GeneChip Human 2.0 ST Array (Affymetrix, Santa Clara, CA) CytoScan HD Cytogenetics Solution (Affymetrix) platforms,...
Cutaneous squamous cell carcinoma (cSCC) is the second most common malignancy in humans and approximately 5% metastasize, usually to regional lymph nodes. Epigenetic regulation of gene expression may allow tumoral cells acquire new functions order escape from primary tumor. The aim this study was investigate function proteins Polycomb family epigenetic regulators metastatic process cSCC. A higher RING1B EZH2 detected by immunohistochemistry a series cSCC tumors that metastasized (MSCCs) when...
The clinical concept of urticaria embraces a heterogeneous group conditions classified according to their course as acute (lasting less than 6 weeks) or chronic weeks more). Chronic may be either spontaneous induced. Few tools are available for monitoring the various forms this disease evaluating its impact on quality life. recently developed Urticaria Control Test evaluate control is in German, original language, and American English. To culturally adapt long short versions Castilian...
Anti-p200 pemphigoid is a rare autoimmune subepidermal blistering disease characterized by the presence of circulating immunoglobulin G antibodies directed against laminin gamma-1, 200-kDa protein located in lamina lucida basement membrane. We review clinical, histopathological and immunological characteristics first 2 cases described Spain. shares immunopathological findings with epidermolysis bullosa acquisita, main entity differential diagnosis. However, its management follows same...
case report, contact dermatitis, drug-induced photosensitivity,
A 23-year-old woman was referred for treatment of multiple papular lesions on the vulvae that patient had noticed 1 year earlier. The not changed in number or size and were asymptomatic. She received several treatments condyloma accuminatum, such as imiquimod podophyllotoxin without any improvement. No history sexually transmitted infections reported. physical examination revealed tiny, smooth, skin-colored papules (arrows), symmetrically distributed inner sides her labia minora introitus...