Lesley M. Arnold

ORCID: 0000-0003-0393-9948
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About
Contact & Profiles
Research Areas
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Musculoskeletal pain and rehabilitation
  • Pain Management and Placebo Effect
  • Health Systems, Economic Evaluations, Quality of Life
  • Pediatric Pain Management Techniques
  • Geographic Information Systems Studies
  • Data Management and Algorithms
  • Obsessive-Compulsive Spectrum Disorders
  • Eating Disorders and Behaviors
  • Semantic Web and Ontologies
  • Body Image and Dysmorphia Studies
  • Coastal and Marine Dynamics
  • Bipolar Disorder and Treatment
  • Advanced Database Systems and Queries
  • Cerebral Palsy and Movement Disorders
  • Childhood Cancer Survivors' Quality of Life
  • Treatment of Major Depression
  • Health, psychology, and well-being
  • Pain Mechanisms and Treatments
  • Psychosomatic Disorders and Their Treatments
  • Schizophrenia research and treatment
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Infant Development and Preterm Care
  • Myofascial pain diagnosis and treatment
  • Scientific Computing and Data Management

University of Cincinnati
2009-2024

University of Cincinnati Medical Center
2013-2023

Curtin University
1995-2020

CRC for Spatial information
2015-2019

University of Michigan
2018

Pfizer (United States)
2007-2015

Université de Sherbrooke
2015

Australian National University
2015

Cincinnati Children's Hospital Medical Center
2010-2012

Eli Lilly (United States)
2006-2012

Binge eating disorder is associated with obesity. Topiramate an antiepileptic agent weight loss. The objective of this study was to evaluate topiramate in the treatment binge obesity.For 14-week, double-blind, flexible-dose (25-600 mg/day) trial, 61 outpatients (53 women, eight men) who were obese (body mass index >/=30 kg/m(2)) randomly assigned receive (N=30) or placebo (N=31). primary efficacy measure frequency. analysis a repeated-measures random regression treatment-by-time as effect...

10.1176/appi.ajp.160.2.255 article EN American Journal of Psychiatry 2003-01-31

Article AbstractObjective: To assess the co-occurrence offibromyalgia with psychiatric disorders in participants of afibromyalgia family study. Method: Patients (probands) fibromyalgia,control probands rheumatoid arthritis, and first-degreerelatives both groups completed a structured clinicalinterview tender point examination. The oddsratio (OR) (the odds lifetime comorbid DSM-IV disorder anindividual fibromyalgia divided by lifetimecomorbid an individual without fibromyalgia, adjustedfor...

10.4088/jcp.v67n0807 article EN The Journal of Clinical Psychiatry 2006-08-15

To assess the efficacy and safety of gabapentin in patients with fibromyalgia.A 12-week, randomized, double-blind study was designed to compare (1,200-2,400 mg/day) (n=75 patients) placebo for treating pain associated fibromyalgia. The primary outcome measure Brief Pain Inventory (BPI) average severity score (range 0-10, where 0=no 10=pain as bad you can imagine). Response treatment defined a reduction >or=30% this score. analysis continuous variables longitudinal intent-to-treat sample,...

10.1002/art.22457 article EN Arthritis & Rheumatism 2007-03-28

The objective of the module was to (1) establish a core domain set for fibromyalgia (FM) assessment in clinical trials and practice, (2) review outcome measure performance characteristics, (3) discuss development responder index FM trials, (4) markers, (5) cognitive dysfunction, (6) research agenda outcomes research. Presentations at included: Results univariate multivariate analysis 10 4 drugs, mapping key domains identified previous patient focus group: Delphi exercises...

10.3899/jrheum.090367 article EN The Journal of Rheumatology 2009-10-01

Abstract Objective In evaluating the effectiveness of fibromyalgia (FM) therapies, it is important to assess impact those therapies on full array domains considered by both clinicians and patients. The objective this research was identify prioritize key clinically relevant impacted FM that should be evaluated outcome assessment instruments used in clinical trials, approach consensus among patients priority assessed care research. Methods Group achieved using Delphi method, a structured...

10.1002/art.23826 article EN Arthritis Care & Research 2008-06-24

Abstract Objective Juvenile fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder in children and adolescents for which there are no evidence‐based treatments. The objective of this multisite, single‐blind, randomized clinical trial was to test whether cognitive–behavioral therapy (CBT) superior (FM) education reducing functional disability, pain, symptoms depression juvenile FMS. Methods Participants were 114 (ages 11–18 years) with After receiving stable medications 8...

10.1002/art.30644 article EN Arthritis & Rheumatism 2011-11-22

<h3>Context</h3> Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied. <h3>Objective</h3> To identify how sequence onsets a disorder and is associated with subsequent course each condition. <h3>Design</h3> Inception cohort. <h3>Setting</h3> Academic medical center. <h3>Patients</h3> Patients (N = 144) were studied who met criteria for I (manic or mixed), 12 to 45 years old, had no previous hospitalizations...

10.1001/archpsyc.64.1.57 article EN Archives of General Psychiatry 2007-01-01

To estimate the minimum clinically important difference (MCID) for several pain measures obtained from Brief Pain Inventory (BPI) patients with fibromyalgia.Data were pooled across 12-week treatment periods 4 randomized, double-blind, placebo-controlled studies designed to evaluate safety and efficacy of duloxetine fibromyalgia. Each study enrolled subjects American College Rheumatology--defined fibromyalgia who presented moderate severe pain. The MCIDs BPI average item score severity (the...

10.1002/acr.20449 article EN Arthritis Care & Research 2011-02-10

This prospective longitudinal study examined the long-term physical and psychosocial outcomes of adolescents with juvenile-onset fibromyalgia (JFM), compared healthy control subjects, into early adulthood.Adolescent patients JFM initially seen at a pediatric rheumatology clinic (n = 94) age- gender-matched subjects 33) completed online measures demographic characteristics, pain, functioning, mood symptoms, health care utilization ∼6 years' follow-up (mean age: 21 years). A standard in-person...

10.1542/peds.2013-2220 article EN PEDIATRICS 2014-02-25

This manuscript, developed by a group of chronic pain researchers and clinicians from around the world, aims to address state knowledge about fibromyalgia (FM) identify ongoing challenges in field FM other syndromes that may be characterized centralization/amplification/hypersensitivity. There have been many exciting developments research studies pathophysiology treatment related potential improve recognition management patients with conditions FM-like pain. However, much new information has...

10.1097/ajp.0000000000000354 article EN Clinical Journal of Pain 2016-03-29

Article AbstractBackground: Psychogenic excoriation, characterized by excessivescratching or picking of the skin, is not yet recognized as a symptom distinct DSM-IVdisorder. The purpose this study was to provide data regarding demographics,phenomenology, course illness, associated psychiatric comorbidity, and family historyof subjects with psychogenic excoriation. Method: Thirty-four consecutive were recruited from anoutpatient dermatology practice advertisement. Subjects completed...

10.4088/jcp.v59n1003 article EN The Journal of Clinical Psychiatry 1998-10-15
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