- Pain Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Pain Management and Placebo Effect
- Pain Management and Treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cervical and Thoracic Myelopathy
- Osteoarthritis Treatment and Mechanisms
- Botulinum Toxin and Related Neurological Disorders
- Myofascial pain diagnosis and treatment
- Pain Management and Opioid Use
- Anesthesia and Pain Management
- Heart Rate Variability and Autonomic Control
- Peripheral Nerve Disorders
- Acupuncture Treatment Research Studies
- Total Knee Arthroplasty Outcomes
- Shoulder Injury and Treatment
- Olfactory and Sensory Function Studies
- Healthcare and Venom Research
- Stress Responses and Cortisol
- Knee injuries and reconstruction techniques
- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Nerve Injury and Rehabilitation
- Intensive Care Unit Cognitive Disorders
Aichi Medical University
2016-2025
Aichi Medical University Hospital
2021-2024
Research Organization of Information and Systems
2019-2020
Nagoya Gakuin University
2017
Creative Research Enterprises (United States)
2017
Chiba University
2016
Kio University
2014
Sapporo Medical University
2014
Yamaguchi University
2014
Toho University
2014
Background Chronic pain is recognized as a public health problem that affects the general population physically, psychologically, and socially. However, there little knowledge about associated factors of chronic pain, such influence weather, family structure, daily exercise, work status. Objectives This survey had three aims: 1) to estimate prevalence in Japan, 2) analyze these factors, 3) evaluate social burden due pain. Methods We conducted cross-sectional postal sample 6000 adults aged...
Low back pain (LBP) is the most common cause of chronic pain. Numerous clinical scales are available for evaluating pain, but their objective criteria in management LBP patients remain unclear. This study aimed to determine an cutoff value a change Pain Intensity Numerical Rating Scale (ΔPI-NRS) three months after treatment. Its utility was compared with changes six commonly used patients: Disability Assessment (PDAS), Self-Efficacy Questionnaire (PSEC), Catastrophizing (PCS), Athens...
This manuscript, developed by a group of chronic pain researchers and clinicians from around the world, aims to address state knowledge about fibromyalgia (FM) identify ongoing challenges in field FM other syndromes that may be characterized centralization/amplification/hypersensitivity. There have been many exciting developments research studies pathophysiology treatment related potential improve recognition management patients with conditions FM-like pain. However, much new information has...
This study marks the first epidemiological evaluation of prevalence and burden chronic neuropathic pain (NeP) in an Asian population. The objective this nationwide cross-sectional was to identify characteristics individuals with NeP, detect NeP features that affect their quality life (QOL), demonstrate negative effects on social daily living as well comorbidities including depression, anxiety sleep disorders.We mailed a cross-sectional, population-based survey random sample 10,000 Japanese...
Classification of musculoskeletal pain based on underlying mechanisms (nociceptive, neuropathic, and nociplastic pain) is challenging. In the absence a gold standard, verification features that could aid in discrimination between these clinical practice research depends expert consensus. This Delphi consensus study aimed to: (1) identify assessment findings are unique to mechanism category or shared no more than 2 categories (2) develop ranked list candidate potentially discriminate...
Study Design. A retrospective clinical study was conducted. Objective. To investigate the relative safety of anterior microsurgical decompression with iliac strut graft fusion versus laminoplasty for a massive ossified posterior longitudinal ligament in cervical spine. Summary Background Data. The question how treatment myelopathy associated can be improved remains unclear. Methods. Addressing this involved analyzing data 26 patients who had undergone either an (n = 14) or procedure 12)...
Objective. Although severe knee osteoarthritis with refractory pain is commonly treated surgically, this often not an option for patients poor health status or unwillingness to undergo major surgery. We examined the efficacy of radiofrequency application sensory nerves as a novel alternative treatment pain. Methods. This study was open-label, nonrandomized, and controlled study. Patients complaining anteromedial associated radiological (moderate severe) were included. They assigned one two...
We conducted a cross-sectional, Internet-based survey with nationally representative sample of Japanese adults to assess the prevalence and characteristics failed back surgery syndrome (FBSS). Data regarding residual symptoms patient satisfaction from an online 1842 lumbar patients revealed FBSS be 20.6% (95% confidence interval [CI], 18.8-22.6). The low pain, dull ache, numbness, cold sensations, paresthesia after was 94.0%, 71.1%, 69.8%, 43.3%, 35.3%, respectively. With logistic regression...
Patients with spinal cord injury (SCI) commonly experience central neuropathic pain (CNeP), which is challenging to treat. Mirogabalin effective for peripheral pain, but evidence CNeP lacking.This randomized, double-blind, placebo-controlled, phase 3 study investigated mirogabalin efficacy and safety the treatment of in patients traumatic SCI. Adult from 120 sites throughout Japan, Korea, Taiwan were randomized (1:1) receive placebo or (5 mg twice daily [BID] 1 week, 10 BID 15 12 weeks)....
In the management of clinical low back pain (LBP), actual damage to lower areas such as muscles, intervertebral discs etc. are normally targeted for therapy. However, LBP may involve not only sensory pain, but also underlying affective which play an important role overall in painful events. Therefore we hypothesized that visualization a event trigger memories, thus provoking dimension pain. The present study investigated neural correlates affect processing subjects with (n = 11) and without...
An epidemiological survey conducted in Japan fiscal year 2010 revealed a high prevalence of chronic musculoskeletal pain, low patient satisfaction with treatment, incidence protracted treatment lasting or more, and reduced quality life. To improve the current system for treating it is important to identify risk factors, including characteristics, developing pain. Thus, we sought determine new pain Japanese population, as well persistence rate, associated state by repeating postal nationwide...
A task force of the International Association for Study Pain (IASP) has developed a classification chronic pain ICD-11 consisting seven major categories. The objective was to test whether proposed categories were exhaustive and mutually exclusive. In addition, perceived utility diagnoses raters' subjective diagnostic certainty be assessed.Five independent centers in three continents coded 507 consecutive patients. raters received definitions main asked allocate each patient. they indicate...
Acupressure on local and distal acupuncture points might result in sedation relaxation, thereby reducing chronic neck pain. The aim was to investigate the effect of acupressure at (LP) (DP) females with Thirty-three were assigned three groups: control group did not receive any stimuli, LP received points, GB 21, SI 14 15, DP LI 4, 10 11. Verbal rating scale (VRS), Neck Disability Index (NDI), State-Trait Anxiety Inventory (STAI), muscle hardness (MH), salivary alpha-amylase (sAA) activity,...
Retrospective clinical review and prospective report of postoperative delirium after cervical spine surgeries.To investigate factors contributing to the development surgery see whether amended therapeutic protocols could improve or alter outcomes.Important consequences for orthopedic patients include impaired recovery increased morbidity mortality. Although its risk have been reported in surgery, there are a very few reports regarding surgery.Eighty-one myelopathy were retrospectively...
Weather changes accompanied by decreases in barometric pressure are suggested to trigger meteoropathy, i.e., weather-related pain. We previously reported that neuropathic pain-related behavior rats is aggravated lowering pressure, and this effect abolished inner ear lesions. These results suggest mechanisms increase vestibular neuronal activity may parallel those contribute meteoropathy generation. However, it remains unknown whether activate activity. To address issue, we used expression of...
Abstract It has been postulated that physical immobilization is an essential factor in developing chronic pain after trauma or surgery extremity. However, the mechanisms of sustained immobilization‐induced remain poorly understood. The present study, therefore, aimed to develop a rat model for post‐cast ( CPCP ) and clarify mechanism(s) underlying . To investigate effects cast on behaviours rats, one hindlimb was immobilized 2 weeks with remobilization conducted 10 weeks. Cast induced muscle...
Abstract Background The subchondral bone of the distal femur is a source pain caused by osteoarthritis ( OA ) or spontaneous osteonecrosis knee. However, nociceptive phenotype dorsal root ganglia DRG neurons innervating in rat knee joints has not been clarified. Methods Retrograde labelling was used to identify afferents and joint rats. markers [calcitonin gene‐related peptide CGRP ), tyrosine receptor kinase A TrkA neurofilament 200 NF 200) isolectin B 4 IB 4)], segmental distribution soma...