A5053938835- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Optical Imaging and Spectroscopy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Traumatic Brain Injury and Neurovascular Disturbances
- Lanthanide and Transition Metal Complexes
- Lower Extremity Biomechanics and Pathologies
- Prostate Cancer Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Advanced X-ray and CT Imaging
- Bone and Joint Diseases
- Bone health and osteoporosis research
- Pulmonary Hypertension Research and Treatments
- Pelvic and Acetabular Injuries
- Virus-based gene therapy research
- Atomic and Subatomic Physics Research
- Cardiovascular Conditions and Treatments
- Vascular Malformations Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Liver Disease Diagnosis and Treatment
- Seismic Imaging and Inversion Techniques
- Cardiovascular Disease and Adiposity
Highland Community College - Illinois
2015-2024
Philips (United States)
2015-2024
The Ohio State University
2022
The Ohio State University Wexner Medical Center
2017
Philips (India)
2011
Philips (Finland)
2005
Procter & Gamble (India)
1989
Neurological Surgery
1987
Cleveland Clinic
1987
Abstract The circulatory changes in the cortex around a cerebral arteriovenous malformation (AVM) were studied 18 patients. AVMs had rapid circulation times with early draining veins on angiography. Local cortical blood flow (ICoBF) was measured cortically applied thermister/Peltier stack arrays. more pronounced effect ICoBF at 2- to 4-cm distance from AVM margin than adjacent cortex. Mean preexcision 62.9 ± 6.7 (SE) ml/100 g/minute (i.e., similar normal controls) near and 43.0 4.2 far...
We propose a new method for generating synthetic CT images from modified Dixon (mDixon) MR data. The is used attenuation correction (AC) when reconstructing PET data on abdomen and pelvis. While does not intrinsically contain any information about photon attenuation, AC needed in PET/MR systems order to be quantitatively accurate meet qualification standards required use many multi-center trials. Existing MR-based generation methods either advanced sequences that have long acquisition time...
Regional arterial CO2 tension (PaCO2) reactivity of cerebral blood flow (CBF) and the effect PaCO2 on spatial temporal heterogeneity CBF were investigated by using autoradiographically determined in rat middle artery occlusion model after a 2-h period under pentobarbital anesthesia to clarify relation between reactivity, heterogeneity, cycling CBF. was adjusted one four levels. cortical areas white matter tissue fractionation [14C]iodoantipyrine [( 14C]IAP) combination with vessel mapping...
Accurate photon attenuation assessment from MR data remains an unmet challenge in the thorax due to tissue heterogeneity and difficulty of lung imaging. As thoracic tissues encompass whole physiologic range absorption, large errors can occur when using, for example, a uniform, water-equivalent or soft-tissue-only approximation. The purpose this study was introduce method voxel-wise synthetic CT (sCT) generation correction (AC) PET/MR MR-only radiation treatment planning (RTP).Acquisition: A...
<h3>BACKGROUND AND PURPOSE:</h3> Spiral MR imaging has several advantages compared with Cartesian that can be leveraged for added clinical value. A multicenter multireader study was designed to compare spiral standard-of-care postcontrast structural brain on the basis of relative performance in 10 metrics image quality, artifact prevalence, and diagnostic benefit. <h3>MATERIALS METHODS:</h3> Seven sites acquired 88 total subjects. For each subject, 2 scans: a 2D T1 spin-echo, 1 4 routine...
Computed tomography (CT) provides information for diagnosis, PET attenuation correction (AC), and radiation treatment planning (RTP). Disadvantages of CT include poor soft tissue contrast exposure to ionizing radiation. While MRI can overcome these disadvantages, it lacks the photon absorption needed AC RTP. Thus, an intelligent transformation from MR CT, i.e., MR-based synthetic generation, is great interest as would support PET/MR MR-only Using pulse sequence that combines ultra-short echo...
Objective The aim of this study was to demonstrate the feasibility in vivo perforator visualization by a newly proposed magnetic resonance–based phase contrast angiography (pPCA) technique for deep inferior epigastric (DIEP) flap surgery and prospectively compare its image quality clinical value with computed tomographic (CTA), state-of-the-art imaging technique. Materials Methods Institutional review board approval informed consent were obtained. DIEP pPCA CTA data acquired 10 female...
To assess whether cardiac MRI or various biomarkers can be used to detect myocardial ischemia and fibrosis in dogs with cardiomegaly secondary myxomatous mitral valve disease (MMVD).6 naturally occurring stage B2 MMVD being treated only pimobendan without enalapril 6 control no disease. All were ≥ 5 years old systemic illness.Serum troponin I concentrations measured, anesthetized for ECG-triggered acquisition of native T1- T2-weighted images. Gadolinium contrast was administered evaluate...
To describe a rapid T2*-weighted (T2*W), three-dimensional (3D) echo planar imaging (EPI) sequence and its application in mapping local magnetic susceptibility variations 3 Tesla (T) prostate MRI. compare the sensitivity of T2*W EPI with routinely used T1-weighted turbo-spin (T1W TSE) detecting hemorrhage implications on sequences sensitive to field inhomogeneities such as MR spectroscopy (MRS).B(0) weighted was performed using 3D featuring 2D spatial excitation pulse gradients spiral...
Cerebral cortical blood flow (lCoBF) and metabolic rate for oxygen (lCoMRO2) were studied in eight patients undergoing intracranial aneurysm clipping. The anesthetized with fentanyl 10 micrograms/kg 70% nitrous oxide combined 30% oxygen. Hypotension was induced isoflurane. A thermal diffusion probe used to measure lCoBF, arterial cerebral venous samples obtained measurement of arterio-cerebral O2 content difference. Measurements made prior hypotension, during hypotension (to mean pressure...
Dixon-based magnetic resonance imaging (MRI) intramuscular proton density fat fraction (PDFF) is a potentially useful biomarker of muscle quality. However, multi-vendor, multi-site reproducibility PDFF quantification, required for large clinical studies, can be strongly dependent on acquisition and processing. The purpose this study was (I) to develop 6-point Dixon MRI-based processing technique reproducible quantification thigh PDFF; (II) evaluate the ability detect differences in status...
Abstract Background ARIA is a common side effect of aducanumab, the first anti‐amyloid pharmacotherapy approved by US Food and Drug Administration (FDA) to treat Alzheimer’s disease. Regular MRI required FDA detect monitor different forms during initiation therapy. protocols must be a) high resolution abnormalities with sensitivity, b) fast accommodate workflow ensure patient compliance c) standardized maximize data acquisition consistency across sites. Based on vendor agnostic protocol...
Background To evaluate whether parallel radiofrequency transmission (mTX) can improve the symmetry of left and right femoral arteries in dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) prostate bladder cancer. Methods Eighteen 24 cancer patients underwent 3.0 Tesla DCE-MRI scan with a single channel coil. Subsequently, 21 were scanned using dual mTX upgrade. The precontrast signal ( ) maximum enhancement ratio (MER) measured both arteries. Within patient cohort, MER artery to...
Apparent diffusion coefficient (ADC) metric is evaluated as a potential alternative to biopsy for disease grading and therapy response assessment in bone marrow of myelofibrosis (MF) patients. Spatially dependent bias weighting due systematic gradient nonlinearity (GNL) results false heterogeneity ADC maps over the imaged space. Here we illustrate deployment prospective GNL correction based on technology developed an academic industrial partnership reduce technical variability MF clinical...
The brain is an organ of interest in high-consequence infectious disease. Subtle blood-brain-barrier disruption and edema can be identified quantified using T<sub>2</sub> relaxation time as a biomarker. Accuracy required to correlate changes imaging findings with biological processes therapeutic effectiveness. Dual echo Fluid-Attenuated Inversion Recovery images, which minimizes the partial volume effects from cerebrospinal fluid, used quantify relaxation. This sequence also meets...
Abstract Background ARIA is a common side effect of aducanumab, the first anti‐amyloid pharmacotherapy approved by US Food and Drug Administration (FDA) to treat Alzheimer’s disease. Regular MRI required FDA detect monitor different forms during initiation therapy. protocols must be a) high resolution abnormalities with sensitivity, b) fast accommodate workflow ensure patient compliance c) standardized maximize data acquisition consistency across sites. Based on vendor agnostic protocol...