A5028123620- Antibiotic Use and Resistance
- Pectus Deformity Diagnosis and Treatment
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Congenital Diaphragmatic Hernia Studies
- Antibiotics Pharmacokinetics and Efficacy
- Pleural and Pulmonary Diseases
- Menopause: Health Impacts and Treatments
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Fungal Infections and Studies
- Pneumonia and Respiratory Infections
- Craniofacial Disorders and Treatments
- Respiratory and Cough-Related Research
- Systemic Lupus Erythematosus Research
- Scoliosis diagnosis and treatment
- Acute Ischemic Stroke Management
- Spinal Fractures and Fixation Techniques
- Estrogen and related hormone effects
- Plant and fungal interactions
- Urinary Tract Infections Management
- Infections and bacterial resistance
- Nosocomial Infections in ICU
- Lung Cancer Diagnosis and Treatment
- Dupuytren's Contracture and Treatments
Peking Union Medical College Hospital
2017-2025
Sir Run Run Shaw Hospital
2024-2025
Zhejiang University
2024-2025
Shaoxing People's Hospital
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2025
First Affiliated Hospital of Fujian Medical University
2014-2025
Fujian Medical University
2014-2025
National Clinical Research Center for Digestive Diseases
2025
Ministry of Education of the People's Republic of China
2025
Second Military Medical University
2024
Abstract Background Carbapenem-resistant (CR) Gram-negative pathogens are recognized as a major health concern. This study examined the prevalence of infections due to 4 CR species (Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli) in United States assessed their impact on hospital stays mortality. Methods Hospitalized patients with laboratory-confirmed infection any were identified from Premier Healthcare Database. Proportions calculated by...
Abstract Background Carbapenem-resistant (CR) Acinetobacter baumannii is a concerning pathogen in the USA and worldwide. Methods To assess comparative burden of CR vs carbapenem-susceptible (CS) A. , this retrospective cohort study analyzed data from adult patients 250 US hospitals Premier HealthCare Database (2014–2019). The outcomes included hospital length stay (LOS), intensive care unit (ICU) utilization, discharge status, in-hospital mortality, readmission rates charges. Logistic...
ABSTRACT Objective: To assess oral health–related quality of life (OHRQoL) in young adult patients with malocclusion and to measure the association between orthodontic treatment need OHRQoL. Materials Methods: The study sample comprised 190 adults aged 18 25 years who were attending clinics at Faculty Dentistry. Index Orthodontic Treatment Need-Dental Health Component was used need. Each participant assessed for OHRQoL before after by using Oral Impact Profile, Chinese version (OHIP-14)....
Stenotrophomonas maltophilia is an opportunistic pathogen observed in both nosocomial and community-onset infections. S. intrinsically resistant to many currently available broad-spectrum antibiotics often not included antimicrobial resistance surveillance studies or stewardship programs' guidelines.A retrospective cohort study of patients with bloodstream infection (BSI) the United States was conducted using 2010-2015 US Premier Healthcare Database. This described patient characteristics,...
The 2023 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) antiphospholipid syndrome (APS) classification criteria were developed with higher specificity but lower sensitivity compared the 2006 Sydney revised criteria.
ObjectiveTo estimate the incidence and recurrence of breast cancer (BC) in patients with vulvovaginal atrophy (VVA) treated ospemifene matched untreated VVA using real-world data.Study designRetrospective cohort study.Main Outcome Measures: were identified from 2011–2018 US MarketScan® insurance claims database. For incidence, ospemifene-treated without evidence BC prior to index treatment two controls similarly history on age, year, geographic region, Charlson Comorbidity categories,...
The risk of congestive heart failure (CHF) is significantly affected by obesity. However, data on the association between visceral obesity and CHF remain limited. We explored relationship cardiometabolic index (CMI).
The international PROVE retrospective chart-review study aims to assess the real-world effectiveness and safety of cefiderocol for treatment patients with carbapenem-resistant Gram-negative infections.
Abstract Background Urinary tract infections (UTIs) are the most common caused by Gram-negative bacteria and represent a major healthcare burden. Carbapenem-resistant (CR) strains of Enterobacterales non-lactose fermenting pathogens further complicate treatment approaches. Methods We conducted retrospective analysis US Premier Healthcare Database (2014–2019) in hospitalised adults with UTI to estimate burden CR UTIs among patients or without concurrent bacteraemia. Results Among 47,496...
Background: This study aimed to explore the association of cardiometabolic index (CMI), CMI-age, visceral adiposity (VAI), and VAI-age with heart failure (HF) compare those indicators for early identification HF.
Background: Terbinafine is an established drug for the treatment of toenail onychomycosis. Minimizing total dose terbinafine and giving it intermittently could improve tolerability as well compliance, provided efficacy not compromised. Objective: Two identical trials were conducted to compare efficacy, safety current standard regimen 250 mg daily with a new formulation given three cycles 2 weeks (350 daily) followed by off treatment. Methods: A 2005 patients clinical diagnosis subungual...
Our group, in collaboration with seven other laboratories, has recently developed a method to determine the susceptibility of dermatophytes.The objective this study was terbinafine profile dermatophyte isolates obtained from patients tinea capitis enrolled two large worldwide clinical trials and investigate whether these susceptibilities differ by geographical location. Methods Susceptibilities were determined according Clinical Laboratory Standards Institute M38-A2 standard.From total 978...
Aim Lusutrombopag is approved for the treatment of thrombocytopenia in chronic liver disease patients undergoing invasive procedures. This real‐world surveillance assesses safety and effectiveness lusutrombopag Japan. Methods ongoing, multicenter, prospective, collecting data from case report forms between October 2016 May 2021. Interim up to September 2018 were used evaluate (adverse events adverse drug reactions [ADRs]) (proportion avoiding preoperative platelet transfusion change count...
The concept of chest wall surgery first appeared in 2008. After more than ten years development, a large number doctors around the world have made great progress, thus making widely spread and appear clinical practice as an independent specialty.
To screen potential nematophagous fungi candidates for the biological control of parasitic nematodes in livestock, vitro and vivo studies native isolates against larvae trichostrongylides were conducted. The predatory activity 16 fungal on sheep feces was assessed. In ten Duddingtonia flagrans , reduction percentage infective (L3) Trichostrongylus colubriformis ranged from 57.21 to 99.83%, that Haemonchus contortus 62.12 99.88%. analysis same assay five Arthrobotrys superba one isolate A....
Pectus excavatum is a common thoracic deformity, and Nuss procedure considered as the standard operation for treatment of this deformity. However, there are often cases failure in clinic. Once such situation occurs, it needs to be operated again. Since can cause adhesions behind sternum bilateral cavities, if still used reoperation, not only very difficult, but also possible heart lung injuries. Therefore, an ideal choice reoperation. Wang new method treat deformity depressed chest wall....
Surgery is the only effective method for treatment of asphyxiating thoracic dystrophy, but it was considered that severe pulmonary hypertension contraindication. We report a 13-year-old male patient dysplasia with hypertension. performed Wenlin procedure him and achieved satisfactory results.
Abstract Objective: Ospemifene is a nonsteroidal selective estrogen receptor modulator (SERM) for the treatment of moderate symptomatic vulvar and vaginal atrophy (VVA) due to menopause. A postauthorization safety study currently examining incidence venous thromboembolism (VTE) among postmenopausal women receiving ospemifene or other SERM (raloxifene, bazedoxifene, tamoxifen, noncancer indications), with untreated VVA. Methods: This interim analysis used US MarketScan Commercial Medicare...
Asphyxiating thoracic dystrophy is a rare and dangerous deformity, its operation challenging. In the past, several operations have been reported, but they all disadvantages. Wang procedure new method for treatment of pectus excavatum. Because this can effectively eliminate various chest wall depressions, we use it in asphyxiating dystrophy. This paper reports 10-year-old child with dystrophy, result was satisfactory.
Simple pectus carinatum can be corrected by general minimally invasive surgery. However, when the is serious, because protrusion obvious and bone rigid, once flattened, there will secondary depression, depression also needs to corrected. In order treat this severe deformity satisfactorily, we designed a special surgical method, which combined operation of Wenlin procedure Wung procedure. Our experience shows that very effective method. This paper reports treatment patient with carinatum.
Serious bloodstream infections (BSIs) are often caused by Gram-negative (GN) bacteria in hospitalized patients. Treatment of these has been further complicated the continued rise and spread drug-resistant pathogens, including carbapenem resistant (CR) strains Enterobacteriaceae, Acinetobacter baumannii, Pseudomonas aeruginosa.This retrospective cohort analysis used real-world data from a large United States hospital-based database to examine association between key clinical outcomes...