A5101948792- MicroRNA in disease regulation
- Circular RNAs in diseases
- Nuclear Receptors and Signaling
- Insect-Plant Interactions and Control
- Insect Resistance and Genetics
- Epigenetics and DNA Methylation
- Insect and Pesticide Research
- RNA Research and Splicing
- Phytoplasmas and Hemiptera pathogens
- Reproductive System and Pregnancy
- Plant Physiology and Cultivation Studies
- Particle physics theoretical and experimental studies
- RNA modifications and cancer
- Insect symbiosis and bacterial influences
- Quantum Chromodynamics and Particle Interactions
- Glioma Diagnosis and Treatment
- Horticultural and Viticultural Research
- Ovarian function and disorders
- Endometriosis Research and Treatment
- Amino Acid Enzymes and Metabolism
- Plant Gene Expression Analysis
- Cancer-related gene regulation
- Quantum Information and Cryptography
- Immunotherapy and Immune Responses
- Connexins and lens biology
Southwest University
2022-2025
Citrus Research Institute
2022-2025
Jiangnan University
2025
Hainan University
2025
South China Normal University
2024
Chinese Academy of Agricultural Sciences
2022-2024
First Affiliated Hospital of Zhengzhou University
2023-2024
Georgetown University
2024
Third Affiliated Hospital of Guangzhou Medical University
2021-2023
Guangzhou Medical University
2021-2023
Circular RNAs (circRNAs) are implicated in various biological processes. As a layer of the gene regulatory network, circRNA expression is also an intermediate phenotype bridging genetic variation and phenotypic changes. Thus, analyzing will shed light on molecular fundamentals complex traits diseases. We systematically characterize 10,559 high-quality circRNAs 589 human dorsolateral prefrontal cortex samples. identify technical factors contributing to heterogeneity associated with levels...
Mutations in isocitrate dehydrogenase 1 (IDH1) and associated CpG island hypermethylation represent early events the development of low-grade gliomas secondary glioblastomas. To identify candidate tumor suppressor genes whose promoter methylation may contribute to gliomagenesis, we compared profiles IDH1 mutant (MUT) wild-type (WT) tumors using massively parallel reduced representation bisulfite sequencing. Reduced sequencing was performed on ten pathologically matched WT MUT glioma samples...
Cold storage preserves lemon fruit quality; however, it can result in significant chilling injury (CI). The effects of pre- and post-harvest methyl jasmonate (MeJA) treatments at four concentrations (0, 0.1, 0.3, 0.5 mM) on CI sensory quality lemons during 80 d 7-10 °C were investigated. Both MeJA reduced CI, weight loss (WL) maintained higher firmness, total soluble solids (TSS), acidity (TA) than the controls. Antioxidant enzyme activities decreased control but increased both MeJA-treated...
Cyetpyrafen is a recently developed acaricide. The citrus red mite, Panonychus citri (McGregor), has significant resistance to cyetpyrafen. However, the molecular mechanism underlying cyetpyrafen in P. remains unclear. Glutathione S-transferases (GSTs) play critical role arthropod pesticide resistance. This study showed that GSTs were potentially related of through synergistic experiments and enzyme activity analysis. An omega-family GST gene, PcGSTO1, was significantly up-regulated egg,...
Spirodiclofen is one of the most widely used acaricides in China. The citrus red mite, Panonychus citri (McGregor) (Acari: Tetranychidae), destructive pests worldwide and has developed a high resistance to spirodiclofen. However, molecular mechanism spirodiclofen P. still unknown. In this study, we identified field spirodiclofen-resistant strain (DL-SC) that showed 712-fold by egg bioassay compared susceptible strain. Target-site was not detected as non-synonymous mutations were found...
Insecticide susceptibility is mainly determined by the insect host, but symbiotic bacteria are also an important affecting factor. In this study, we investigate relationship between structure of gut bacterial symbionts and insecticide in
Overexpression of carboxyl/cholinesterase (CCE) genes has been reported to be associated with many cases pesticide resistance in arthropods. However, it rarely documented that CCE participate spirodiclofen Panonychus citri. In previous research, we found is related increased P450 and enzyme activities P. this study, identified two genes, PcCCE3 PcCCE5, which were significantly upregulated spirodiclofen-resistant strain after exposure spirodiclofen. RNA interference PcCCE5 the susceptibility...
We introduce MiniMax-01 series, including MiniMax-Text-01 and MiniMax-VL-01, which are comparable to top-tier models while offering superior capabilities in processing longer contexts. The core lies lightning attention its efficient scaling. To maximize computational capacity, we integrate it with Mixture of Experts (MoE), creating a model 32 experts 456 billion total parameters, 45.9 activated for each token. develop an optimized parallel strategy highly computation-communication overlap...
Abstract Adhesive hydrogels are emerging as attractive functional materials for various fields, such tissue engineering, wound healing, E‐skins, etc. However, the removal of adhesive from covered area may be painful and cause a secondary damage. In current study, gelatin‐based prepared by cross‐linking with tannic acid 4‐formylphenyl boronic acid, through simultaneous dynamic covalent ester imine bond formations. The obtained not only present self‐healing injectable properties, but also show...
Cyetpyrafen is a newly developed acaricide. The citrus red mite, Panonychus citri (McGregor), an important pest that has resistance to cyetpyrafen. Uridine diphosphate-glycosyltransferases (UGTs) have been widely reported be associated with multiple acaricides. However, it rarely documented UGT genes participate in cyetpyrafen P. citri. In this study, significantly upregulated gene, PcUGT201E1, was identified using transcriptome analysis. Expression of PcUGT201E1 at all stages the...
Blood orange (Citrus sinensis L. Osbeck) is a rare commercial citrus fruit containing abundant anthocyanins and has numerous health benefits. rootstock determines the yield quality. This study evaluated effect of three most commonly used rootstocks on features, color index, physicochemical parameters, anthocyanin accumulation, biosynthetic gene expression, associated enzymes during development ripening ‘Tarocco’ blood orange. The highest content at harvest was found in trees grafted onto...
Abstract Diaphorina citri is a global citrus pest. As vector insect, it can transmit the causative agents of huanglongbing, causing irreversible losses to industry. The acquisition genomic information provide molecular genetic basis for effective control D. . Here, DNBSEQ ™ , Oxford Nanopore Technologies, and Hi‐C technologies are applied generate high‐quality chromosome‐level genome size was 523.78 Mb with scaffold N50 47.05 distributed on 13 chromosomes. A total 250.64 (47.85%) repeat...
Asian citrus psyllid (Diaphorina citri, D. citri) is the important vector of "Candidatus Liberibacter asiaticus" (CLas), associated with Huanglongbing, most devastating disease worldwide. CLas can affect endosymbiont abundance citri. Here, we generated high-quality gut metagenomes Diaphorina citri on condition infected and uninfected. The dataset comprised 6616.74 M 6586.04 raw reads, overage, from uninfected strains, respectively. Taxonomic analysis revealed that a total 1046 species were...
Polycystic ovary syndrome (PCOS) is an endocrine-related follicular developmental disorder that affects 50 %-70 % of reproductive-aged women diagnosed with ovulation-related infertility. Abnormal proliferation and apoptosis granulosa cells (GCs) are thought to be the critical factors leading abnormal maturation follicles. It has been shown microRNAs (miRNAs) exert a significant influence in pathogenesis PCOS; however, relationship between miRNA, PCOS, GC not entirely understood.To clarify...
Abstract Citrus species are among the most economically important fruit crops. Physiological characteristics and molecular mechanisms associated with de-etiolation have been partially revealed. However, little is known about controlling expression function of genes photosynthesis chlorophyll biosynthesis in variegated citrus seedlings. The lower biomass, contents, photosynthetic parameter values recorded for seedlings suggested that was inhibited. Additionally, roots were longer than green...
The effectiveness of ecological security patterns (ESPs) in maintaining regional stability and promoting sustainable development is widely recognized. However, limited research has focused on the early warning risks inherent ESPs. In this study, Guangdong–Hong Kong–Macao Greater Bay Area (GHKMGBA) taken as study area, risk zones are delineated by combining landscape index habitat quality, a multi-level ESP constructed based circuit theory. PLUS model was employed to simulate future built-up...