A5101961645- Antibiotics Pharmacokinetics and Efficacy
- Pesticide Residue Analysis and Safety
- Analytical Chemistry and Chromatography
- Microbial infections and disease research
- Influenza Virus Research Studies
- Analytical Methods in Pharmaceuticals
- Respiratory viral infections research
- Pharmaceutical and Antibiotic Environmental Impacts
- Aquaculture disease management and microbiota
- Bacteriophages and microbial interactions
- Analytical chemistry methods development
- Complex Network Analysis Techniques
- Animal Disease Management and Epidemiology
- Pneumonia and Respiratory Infections
- Caching and Content Delivery
- Virology and Viral Diseases
- Recommender Systems and Techniques
- Occupational and environmental lung diseases
- Antimicrobial Resistance in Staphylococcus
- Inhalation and Respiratory Drug Delivery
- Immune Response and Inflammation
- Pharmacological Effects and Assays
- Antibiotic Resistance in Bacteria
- Social Media and Politics
- Coccidia and coccidiosis research
Ministry of Agriculture and Rural Affairs
2020-2025
Jiangsu Academy of Agricultural Sciences
2016-2025
Microsoft Research Asia (China)
2024
Nanjing Agricultural University
2011-2023
Xiangnan University
2023
First Affiliated Hospital of Gannan Medical University
2022
Microsoft Research (United Kingdom)
2017
Fudan University
2009-2011
Academy of Military Medical Sciences
2011
Yangzhou University
2010
Abstract Outbreaks in fish of motile Aeromonad septicemia (MAS) caused by Aeromonas hydrophila have a great concern worldwide. Here, for the first time, we provide two complete genomes epidemic A. strains isolated China. To gain an insight into pathogenicity , performed comparative genomic analyses five belonging to sequence type (ST) 251, together with environmental strain ATCC 7966 T . We found that known virulence factors, including III secretion system, VI system and lateral flagella,...
Emotional intelligence significantly impacts our daily behaviors and interactions. Although Large Language Models (LLMs) are increasingly viewed as a stride toward artificial general intelligence, exhibiting impressive performance in numerous tasks, it is still uncertain if LLMs can genuinely grasp psychological emotional stimuli. Understanding responding to cues gives humans distinct advantage problem-solving. In this paper, we take the first step towards exploring ability of understand To...
As the wide popularization of online social networks, users are not content only with keeping friendship friends in real life any more. They hope system designers can help them exploring new common interest. However, large amount and their diverse dynamic interests possess great challenges to support such a novel feature networks. In this paper, by leveraging interest-based features, we design general friend recommendation framework, which characterize user interest two dimensions: context...
A method utilizing high-performance liquid chromatography-fluorescence detection (HPLC-FLD) has been developed and refined for the simultaneous of florfenicol (FF) its metabolite amine (FFA) along with three fluoroquinolone (ciprofloxacin (CIP), enrofloxacin (ENR), sarafloxacin (SAR)) residues in different parts eggs (whole egg, egg yolk, albumen). The QuEChERS ("Quick, easy, cheap, effective, rugged, safe") procedure utilized 0.1 M disodium EDTA solution, water, acetonitrile as extractants;...
Air-liquid interface (Ali) systems allow the establishment of a culture environment more representative that in vivo than other systems. They are useful for performing mechanistic studies respiratory epithelial cells as drug permeation barriers and can be used to study interactions between hosts pathogens. However, there have been few concerning Ali cultures primary swine tracheal (STECs) an immortalized STEC line, differences these two remain poorly defined. In this study, we established...
Outline social media networks (OSMNs) such as Twitter provide great opportunities for public engagement and event information dissemination. Event-related discussions occur in real time at the worldwide scale. However, these are form of short, unstructured messages dynamically woven into daily chats status updates. Compared with traditional news articles, rich diverse user-generated content raises unique new challenges tracking analyzing events. Effective efficient modeling is thus essential...
A method based on accelerated solvent extraction (ASE) coupled with gas chromatography tandem mass spectrometry (GC-MS/MS) was developed for the quantitative analysis of spectinomycin and lincomycin in poultry egg (whole egg, albumen yolk) samples. In this work, samples were extracted purified using an ASE350 instrument solid-phase (SPE) cartridges, parameters ASE experimentally optimized. The appropriate SPE cartridges selected, conditions derivatization reaction After derivatization,...
Abstract Swine mycoplasma pneumonia caused by Mycoplasma hyopneumoniae is the most prevalent and frequently occurring chronic respiratory disease in pigs worldwide. Pig breeds China are more susceptible to , understanding reasons for their susceptibility crucial prevention control of swine pneumonia, as well promoting healthy development industry. has limited biosynthesis metabolism, harsh requirements nutrients, thus it necessary add approximately 15%-20% porcine serum medium during vitro...
Mycoplasmas are a group of prokaryotes without cell walls that have evolved through several rounds degenerative evolution. With low DNA G + C content and definitively long genetic lineages, mycoplasmas thought to be in state rapid However, little associated evidence has been provided. Enolase is key enzyme glycolysis widely found all species from the three domains, it evolutionarily conserved. In our previous studies, enolase acted as virulence factor participated cell-surface adhesion...
A sensitive and robust method is presented for the simultaneous determination of amoxicillin (AMO) ampicillin (AMP) in eggs by reversed-phase high-performance liquid chromatography with fluorescence detection (RP-HPLC-FLD). This used a simple liquid-liquid extraction samples acetonitrile dichloromethane as precipitation proteins solvent. AMO AMP reacted salicylaldehyde to form fluorescent derivatives, which were then analyzed RP-HPLC-FLD. Separation was carried out on an Athena C18 column...