A5059393779- Autoimmune Neurological Disorders and Treatments
- Salivary Gland Disorders and Functions
- Peripheral Neuropathies and Disorders
- Vestibular and auditory disorders
- Multiple Sclerosis Research Studies
- Myasthenia Gravis and Thymoma
- Olfactory and Sensory Function Studies
- Neurological disorders and treatments
- Thyroid Disorders and Treatments
- Ocular Oncology and Treatments
- Glycogen Storage Diseases and Myoclonus
- Hereditary Neurological Disorders
- Systemic Sclerosis and Related Diseases
- Drug-Induced Ocular Toxicity
- Functional Brain Connectivity Studies
- CNS Lymphoma Diagnosis and Treatment
- Migraine and Headache Studies
- Hepatitis C virus research
- Systemic Lupus Erythematosus Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pituitary Gland Disorders and Treatments
- Glioma Diagnosis and Treatment
- Glaucoma and retinal disorders
- Restless Legs Syndrome Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
Wroclaw Medical University
2014-2023
Weatherford College
2021
University of Wrocław
2021
University of Warsaw
2013
Niepubliczna Wyższa Szkoła Medyczna
1998-2009
Neurology, Inc
2004
Abstract Background Chronic exposure to heavy metals affects various organs, among them the brain and peripheral nerves. Polyneuropathy is mainly length-dependent with predominantly sensory symptoms. There have been few studies on small fiber neuropathy due metal intoxication. Methods We investigated 41 industry workers, mean age 51.3 ± 10.5 years, at least 5 years’ professional metals, 36 age- sex-matched healthy controls. performed neurological examinations, assessed blood levels of...
Abstract Thyroid dysfunction is very often accompanied by cognitive and affective disorders. The frequency of these disorders in patients with compensated Hashimoto’s thyroiditis (HT) unknown. aim the present study was to evaluate brain euthyroid HT means event-related potentials (ERP) magnetic resonance spectroscopy (MRS) correlate it function. 68 (59 female, 9 male) 45 healthy controls were included study. All underwent ERP including an analysis N200 P300 response parameters. MRS voxels...
: There is an increasing number of patients worldwide with sleep disturbances and diabetes. Various disorders, including long or short duration poor quality numerous causes, may increase the risk Some symptoms diabetes, such as painful peripheral neuropathy nocturia, associated other breathing disorders movement influence quantity. Both diabetes lead to cognitive impairment. The development impairment in diabetic be related vascular non-vascular factors, hypoglycemia, hyperglycemia, central...
Multiple sclerosis (MS) is frequently accompanied by visual symptoms including those related to retinal disorders. Since they may be a consequence of an autoimmune reaction, we examined whether sera patients with diagnosed MS and changes in visual-evoked potentials contain antibodies against antigens (retAgs). Immunoblot analysis revealed that recognized mainly 46-kD antigen, 41-kD arrestin, smaller extent also 70-, 56-, 43-, 36-kD proteins. Patients whose showed the highest reactivity 41-...
Hashimoto's thyroiditis (HT) is the most common autoimmune disease in humans usually associated with subsequent hypothyroidism. The purpose of study was to assess metabolic alterations within normal appearing brain subjects HT using MR spectroscopy (MRS) and correlate MRS measurements hormonal concentrations. Fifty-five patients (mean age 43.5 yrs) 30 healthy controls 42.5 were examined use a 1.5 T scanner. There no signs central nervous system involvement studied group. examinations...
Diagnosis of amyotrophic lateral sclerosis (ALS) is based on clinical criteria and electrophysiological tests (electromyography, transcranial magnetic stimulation). In the search for ALS biomarkers, role imaging procedures currently emphasized, especially modern MR techniques. were performed 15 patients a sex- age-matched control group. The examinations with 1.5-T unit, protocol consisted sagittal T1-weighed images, axial T2-weighed FAT SAT images followed by an diffusion tensor (DTI)...
Background. The present study was aimed to evaluate parameters of visual and brainstem auditory evoked potentials (VEP, BAEP) in euthyreotic Hashimoto’s thyroiditis (HT) patients without central nervous system involvement. Methods. 100 HT (92 women, 8 men), mean age 46.9 years, 50 healthy controls. They underwent a neurological examination, thyroid hormone levels, autoantibody titers, brain imaging. Latencies amplitudes the N75, P100, N145 component VEP I-V components BAEP were analyzed....
Cancer-associated retinopathy (CAR) is a paraneoplastic neurological syndrome resulting in progressive loss of vision and clinical signs retinal degeneration. It associated with various types cancer also considered to be an autoimmune disorder that involves cross-reaction between autoantibodies proteins. The aim this study was establish whether immunoreactivity antigens (RAs) observed patients breast accompanied by any visual impairments.Sera 295 diagnosed were screened for the presence...
IntroductionThe aim of this study was to investigate brain bioelectrical activity disturbances in HCV-positive patients before and 24 weeks after interferon-free therapy (DAA), using visual (VEP) brainstem (BAEP) evoked potentials advanced magnetic resonance techniques.Materials methods11 HCV-infected (6 women, 5 men, mean age 51 years old) 30 healthy controls, sex age-matched, were studied. Clinical neurological examinations, VEP, BAEP, diffusion tensor imaging (DTI) perfusion weighted...
Objectives: Endogenous cognitive event-related potentials (CERPs) reflect higher-level processing of sensory information and can be used to evaluate functions. The aim this paper was determine whether there are any abnormalities in the electrophysiological parameters CERPs patients with primary Sjögren's syndrome (pSS) but without symptoms central nervous system (CNS) involvement or mental disorder. analysis CERP then correlated clinical status some immunological patient group.Method: Thirty...
Abstract Introduction Systemic malignant diseases cause the induction of autoimmunity, for example, paraneoplastic syndromes. There are no proofs syndromes in primary brain tumors. The aim study was to evaluate involvement peripheral nervous system, together with an assessment onconeuronal and antineural antibodies as indicators humoral immune response against system patients Materials Methods Clinical examinations, electrophysiological studies nerves (motor sensory conduction velocity...
Summary The purpose of this study was to assess cerebral microstructural and perfusion changes in patients with chronic hepatitis C virus ( HCV ) infection before after interferon‐free therapy, using advanced magnetic resonance MR techniques. Eleven ‐positive underwent diffusion tensor imaging DTI perfusion‐weighted PWI a 1.5T unit, 24 weeks completion therapy. fractional anisotropy FA apparent coefficient ADC values were obtained from 14 white matter tracts. relative blood volume rCBV flow...
Abstract Introduction Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease of the peripheral nervous system, sometimes including central system. The aim study was assessment prevalence sensory impairment and its reliance on nerve damage in patients with CIDP. Material methods Multimodal (visual—VEP, brainstem auditory—BAEP, somatosensory—SEP) evoked potentials (EPs) were studied 24 diagnosed results compared neurographic parameters responses. control...
Primary Sjogren's syndrome (pSS) is a chronic autoimmune disease. The aim of the study was to establish whether in patients with pSS without central nervous system (CNS) involvement, function portion sensory pathway can be challenged. In 33 clinical features CNS damage and normal head computed tomography scan, somatosensory evoked potentials (SEP) were studied. results compared other parameters disease, particularly immunological status. control group consisted 20 healthy volunteers. Mean...