Clara N. Lee

ORCID: 0000-0003-0514-9448
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About
Contact & Profiles
Research Areas
  • Breast Implant and Reconstruction
  • Patient-Provider Communication in Healthcare
  • Global Cancer Incidence and Screening
  • Reconstructive Surgery and Microvascular Techniques
  • BRCA gene mutations in cancer
  • Cancer survivorship and care
  • Breast Cancer Treatment Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Palliative Care and End-of-Life Issues
  • Digital Imaging in Medicine
  • Trauma and Emergency Care Studies
  • Diversity and Career in Medicine
  • Social Media in Health Education
  • Cervical Cancer and HPV Research
  • Cancer Genomics and Diagnostics
  • Health Literacy and Information Accessibility
  • Patient Dignity and Privacy
  • Body Image and Dysmorphia Studies
  • Colorectal Cancer Screening and Detection
  • Emergency and Acute Care Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Clinical practice guidelines implementation
  • Family Support in Illness
  • Injury Epidemiology and Prevention
  • Facial Rejuvenation and Surgery Techniques

UNC Lineberger Comprehensive Cancer Center
2011-2025

University of North Carolina at Chapel Hill
2011-2025

The Ohio State University
2017-2024

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
2019-2023

The Ohio State University Wexner Medical Center
2020-2023

Washington University in St. Louis
2021

Rice University
2019

Johns Hopkins University
2018-2019

The University of Texas Medical Branch at Galveston
2019

The University of Texas MD Anderson Cancer Center
2018

Background: Current efficacy data supporting the routine use of acellular dermal matrices in postmastectomy tissue expander/implant reconstruction are limited. A multicenter, blinded, randomized controlled study was designed to evaluate effectiveness matrix setting reconstruction. The primary objective determine whether would decrease patient-reported postoperative pain. secondary its accelerate rate expansion. Methods: trial conducted at two U.S. centers from 2008 2011. Immediately...

10.1097/prs.0b013e31825f05b4 article EN Plastic & Reconstructive Surgery 2012-11-01

Although breast-conserving surgery is oncologically safe for women with early-stage breast cancer, mastectomy rates are increasing. The objective of this study was to examine the role reconstruction in surgical management unilateral cancer.A retrospective cohort diagnosed cancer (1998 2011) identified National Cancer Data Base conducted. Rates surgery, and bilateral contralateral prophylactic procedures (per 1000 cases) were measured relation reconstruction. association between treatment...

10.1097/prs.0000000000001276 article EN Plastic & Reconstructive Surgery 2015-05-28

There has been a trend toward limiting perioperative prophylactic antibiotics, based on research not conducted in plastic surgery patients. The authors' university hospital instituted antibiotic prescribing guidelines the Surgical Care Improvement Project. An increased rate of surgical-site infections was noted breast reconstruction authors sought to determine whether change prophylaxis regimen affected rates infections.A retrospective study compared patients undergoing who received...

10.1097/prs.0b013e31825dbefe article EN Plastic & Reconstructive Surgery 2012-05-10

Restoration of form and function after burn injury remains challenging, but emerging laser pulsed light technologies now offer hope for patients with hypertrophic scars, which may be associated persistent hyperemia, chronic folliculitis, intense pruritis, neuropathic pain. In addition to impairing body image, these scars limit functional recovery, compromise activities daily living, prevent return work. Three different platforms are poised alter our reconstructive algorithm: (1)...

10.1155/2012/243651 article EN cc-by Dermatology Research and Practice 2012-01-01

Background: Fat transfer is an increasingly popular method for refining postmastectomy breast reconstructions. However, concern persists that fat may promote disease recurrence. Adipocytes are derived from adipose-derived stem cells and express adipocytokines can facilitate active cancer in laboratory models. The authors sought to evaluate the association between reconstructed recurrence patients diagnosed with local or regional invasive cancers. Methods: A multicenter, case-cohort study was...

10.1097/prs.0000000000002838 article EN Plastic & Reconstructive Surgery 2016-12-29

Objective: To evaluate a web-based breast reconstruction decision aid, BREASTChoice . Summary and Background Data: Although postmastectomy can restore quality of life body image, its morbidity remains substantial. Many patients lack adequate knowledge to make informed choices. Decisions are often discordant with patients’ preferences. Methods: Adult women stages 0–III cancer considering no previous were randomized or enhanced usual care (EUC). Results: Three hundred seventy-six screened; 120...

10.1097/sla.0000000000003444 article EN Annals of Surgery 2019-07-11

Women diagnosed with early stage (I or II) breast cancer face a highly challenging decision - whether not to undergo adjuvant chemotherapy. We developed quality instrument for chemotherapy and sought evaluate its performance.Cross-sectional, mailed survey of recent survivors, providers, healthy controls retest survivors. The includes questions on knowledge personal goals. It results in score concordance score, which reflects the percentage patients who received treatments that match their...

10.1186/1472-6947-12-51 article EN cc-by BMC Medical Informatics and Decision Making 2012-06-08

Women with early-stage breast cancer face a multitude of decisions. The quality decision can be measured by the extent to which treatment reflects what is most important an informed patient. Reliable and valid measures patients' knowledge their goals concerns related treatments are needed assess quality.To identify set key facts relevant each three decisions (surgery, reconstruction adjuvant chemotherapy hormone therapy) evaluate validity methods used them.Candidate were chosen based on...

10.1111/j.1369-7625.2010.00600.x article EN other-oa Health Expectations 2010-06-09

Decisions about breast reconstruction after mastectomy are some of the most difficult decisions a cancer patient makes. To make good decision, should have adequate knowledge specific facts related to and treatment chosen be consistent with patient's personal preferences or goals. We sought identify important goals for mastectomy, compare patients' providers' perspectives. conducted cross-sectional survey survivors providers. Participants rated ranked importance goals/concerns mastectomy....

10.1097/sap.0b013e3181c01279 article EN Annals of Plastic Surgery 2010-04-14

Variation in rates of breast reconstruction after mastectomy has raised concerns about the quality decisions reconstruction. The authors sought to evaluate patient decision making reconstruction, using a validated measure knowledge and preferences related reconstruction.A cross-sectional survey early-stage cancer survivors from four university medical centers was conducted. included measures specific facts, personal goals concerns, involvement making. A multivariable linear regression model...

10.1097/prs.0b013e3181f958de article EN Plastic & Reconstructive Surgery 2011-01-01

What do patients want when looking for an aesthetic surgeon? When faced with attributes like reputation, years in practice, testimonials, photos, and pricing, which is more valuable? Moreover, are procedure-specific? Currently, inadequate evidence exists on most important to patients, our knowledge, none procedure-specific preferences. First, determine the breast augmentation, combined breast/abdominal surgery, facelift using conjoint analysis. Second, test internet crowdsourcing service...

10.1093/asj/sjw143 article EN Aesthetic Surgery Journal 2016-09-20

From MalawiBreast cancer burden is high in low-resource countries.From 1980 to 2010, new breast cases increased by more than 50% worldwide. 1Disease even rapidly low-and middle-income countries (LMICs), where half of now occur.Moreover, disproportionately affects young women LMICs, such that 23% occur among age 15 49 years LMICs versus 10% high-income countries. 1

10.1200/jgo.2015.000430 article EN cc-by-nc-nd Journal of Global Oncology 2015-12-24

This study assesses the usefulness of omentum in reconstruction complex perineal defects, following abdominoperineal resection or pelvic exenteration, for anorectal malignancy. Between 2000 and 2008, 70 patients (mean age: 59 years) with malignancy underwent (n = 57) exenteration 13) were reconstructed by primary repair alone 13), 16), myocutaneous flap 28), 13). Patients without omental flaps compared Student t test chi2 analysis. Omental based on a single pedicle, tunneled retrocolic plane...

10.1097/sap.0b013e3181ce3947 article EN Annals of Plastic Surgery 2010-04-14

Discussions about breast reconstruction should include factual information and consideration of the patient's personal concerns. Providers are familiar with relevant facts but may not know which concerns important to patients. Experience cancer patients has found that providers frequently do their patients' treatment preferences. To help reconstructive surgeons discuss preferences patients, we sought identify women's key related reconstruction. We employed a qualitative design convened...

10.1097/sap.0b013e3181bffc9b article EN Annals of Plastic Surgery 2010-03-30

Road traffic injuries are a major cause of preventable death in sub-Saharan Africa. Accurate epidemiologic data scarce and under-reporting from primary sources is common. Our objectives were to estimate the incidence road deaths Malawi using capture-recapture statistical analysis determine what future efforts will best improve upon this estimate. model combined both police hospital-based registries over one year period (July 2008 June 2009). The mortality incidences 0.075 0.051 deaths/1000...

10.1371/journal.pone.0031091 article EN cc-by PLoS ONE 2012-02-15

Shared decision-making (SDM) is a process through which patients and providers collaborate to select treatment option that aligns with patients' preferences clinical context. SDM can improve decision quality satisfaction. However, vulnerable populations face barriers participation in SDM, exacerbates disparities quality. This perspective article discusses patients, using examples from who made decisions about postmastectomy breast reconstruction. We offer several strategies for practice,...

10.1089/heq.2018.0020 article EN cc-by Health Equity 2018-09-01

Background: Approximately 20% of patients report inadequate discussions with their providers about reconstructive options, an increased frequency reported in non-White women. Eliciting treatment preferences adaptive choice-based conjoint (ACBC) analysis can improve our understanding what patients’ value. We aimed to determine African American (AA) value when considering breast reconstruction options. Methods: Cross-sectional ACBC AA women recruited through community partnerships and academic...

10.1097/prs.0000000000012003 article EN Plastic & Reconstructive Surgery 2025-02-04
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