Kai Wang

ORCID: 0000-0003-0553-5293
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About
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Research Areas
  • Bee Products Chemical Analysis
  • Insect and Pesticide Research
  • Essential Oils and Antimicrobial Activity
  • Plant and animal studies
  • Phytochemicals and Antioxidant Activities
  • Healthcare and Venom Research
  • Insect and Arachnid Ecology and Behavior
  • Natural product bioactivities and synthesis
  • Gut microbiota and health
  • Plant Stress Responses and Tolerance
  • Phytochemistry and Biological Activities
  • Metabolomics and Mass Spectrometry Studies
  • Pharmacological Effects of Natural Compounds
  • Plant responses to water stress
  • Plant Micronutrient Interactions and Effects
  • Insect Pest Control Strategies
  • Sirtuins and Resveratrol in Medicine
  • Medical and Biological Ozone Research
  • Cancer-related molecular mechanisms research
  • Immune Response and Inflammation
  • Asthma and respiratory diseases
  • Biochemical effects in animals
  • Plant Toxicity and Pharmacological Properties
  • Diet and metabolism studies
  • Bioactive Natural Diterpenoids Research

Institute of Apiculture Research
2016-2025

Chinese Academy of Agricultural Sciences
2016-2025

Chinese Academy of Sciences
2021-2025

Shandong Agricultural University
2022-2025

Ningbo Medical Center Lihuili Hospital
2025

Ningbo University
2013-2025

China Agricultural University
2015-2025

Nanjing Medical University
2017-2025

Institute of Biophysics
2025

National Health and Family Planning Commission
2025

Scope Dietary supplementation with polyphenol‐rich propolis can protect against experimentally induced colitis. We examined whether different polyphenol compositions of Chinese (CP) and Brazilian (BP) influence their ability to dextran sulfate sodium (DSS)‐induced colitis in rats. Methods results HPLC‐DAD/Q‐TOF‐MS analysis confirmed that CP BP were dissimilar. Rats given or by gavage (300 mg kg −1 body weight) throughout the study, starting 1 week prior DSS treatment for followed 3 d without...

10.1002/mnfr.201800080 article EN Molecular Nutrition & Food Research 2018-06-11

Chinese propolis has been reported to possess various biological activities such as antitumor. In present study, anticancer activity of ethanol extract (EECP) at 25, 50, 100, and 200 μ g/mL was explored by testing the cytotoxicity in MCF-7 (human breast cancer ER(+)) MDA-MB-231 ER(-)) cells. EECP revealed a dose- time-dependent cytotoxic effect. Furthermore, annexin A7 (ANXA7), p53, nuclear factor- κ B p65 (NF- p65), reactive oxygen species (ROS) levels, mitochondrial membrane potential were...

10.1155/2014/280120 article EN cc-by Evidence-based Complementary and Alternative Medicine 2014-01-01

Honeys produced from medicinal plants hold great promise for human health. Herein, we determined the chemical composition and gastrointestinal protective effects of a novel monofloral honey Prunella vulgaris (PVH). The physicochemical parameters (moisture, sugars, pH, protein content, diastase activity, hydroxymethylfurfural) PVH samples met criteria specified in European Union regulations Chinese National Standards. Fifteen phenolic compounds were identified quantified via high-performance...

10.1039/c9fo00460b article EN Food & Function 2019-01-01

This study aimed to investigate the protective effect of genistein or puerarin on chronic alcohol-induced liver injury in vivo and explore underlying mechanisms hepatoprotective effects. Mice were administered (0.3 mmol kg(-1) body weight) gastrically infused with 50% alcohol once per day for 5 weeks. Levels serum transaminases, hepatic lipids, antioxidant capacities, inflammation, apoptosis, histopathological sections analyzed. Results showed that exhibited similar effects ameliorating...

10.1021/acs.jafc.6b02907 article EN Journal of Agricultural and Food Chemistry 2016-09-09

Our previous reports suggested that dietary supplementation with lysine influenced intestinal absorption and metabolism of amino acids. In this study, we further investigated the effect restriction (30%) on feed intake also tested hypothesis gut microbiome contributed to potential mechanism restriction-mediated feeding behavior. Here, profiled microbial communities by sequencing 16S ribosomal ribonucleic acid (rRNA) genes from samples as well growth performance, serum hormones, transport in...

10.1159/000485782 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2017-01-01

Propolis has abundant polyphenolic constituents and is used widely as a health/functional food. Here, we investigated the effects of polyphenol-rich propolis extracts (PPE) on intestinal barrier function in human epithelial Caco-2 cells, well rats. In PPE increased transepithelial electrical resistance decreased lucifer yellow flux. PPE-treated cells showed expression tight junction (TJ) loci occludin zona occludens (ZO)-1. Confocal microscopy organized expressions proteins related to TJ...

10.3390/nu8050272 article EN Nutrients 2016-05-07

Microplastics (MPs), in the form of fragments and fibers, were recently found honey samples collected Ecuador as well bees from Denmark China. However, little is known about how MPs impact bee health. To fill this knowledge gap, we investigated potential toxicity irregularly shaped polystyrene (PS)-MP on In first experiment its kind with bees, chronically exposed a well-established gut microbiome to small (27 ± 17 µm) or large (93 25 PS-MP at varying concentrations (1, 10, 100 µg mL−1) for...

10.3390/toxics11020100 article EN cc-by Toxics 2023-01-21

Apple pomace (AP) is a highly prevalent waste product worldwide in the fruit processing sector. This study compared chemical profile, antioxidant, and anti-inflammatory activities of crude (CE) an extract purified using XAD-7 resin (PE). The purification process increased total phenolic content, flavonoids, tannins by 3.35, 40.31, 8.87-fold, respectively. main compounds identified PE were phlorizin (20.54 mg/g), chlorogenic acid (10.01 hyperoside (2.77 mg/g). No difference was found between...

10.1016/j.foodchem.2023.137815 article EN cc-by Food Chemistry 2023-10-20
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