A5074324726- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Alzheimer's disease research and treatments
- Insect and Arachnid Ecology and Behavior
- Phytochemicals and Antioxidant Activities
- Healthcare and Venom Research
- Insect and Pesticide Research
- Autophagy in Disease and Therapy
- Mesenchymal stem cell research
- Marine and coastal plant biology
- Telomeres, Telomerase, and Senescence
- Silymarin and Mushroom Poisoning
- Sirtuins and Resveratrol in Medicine
- Pharmacological Effects of Natural Compounds
- Bioinformatics and Genomic Networks
- Cancer Research and Treatments
- Hibiscus Plant Research Studies
- Immune cells in cancer
- Algal biology and biofuel production
- Drug-Induced Hepatotoxicity and Protection
- Seaweed-derived Bioactive Compounds
- Forecasting Techniques and Applications
- Advancements in Transdermal Drug Delivery
- Phytochemical and Pharmacological Studies
- Insurance and Financial Risk Management
Zhejiang University
2016-2025
Central South University
2025
First Affiliated Hospital Zhejiang University
2025
South China University of Technology
2023
Propolis has abundant polyphenolic constituents and is used widely as a health/functional food. Here, we investigated the effects of polyphenol-rich propolis extracts (PPE) on intestinal barrier function in human epithelial Caco-2 cells, well rats. In PPE increased transepithelial electrical resistance decreased lucifer yellow flux. PPE-treated cells showed expression tight junction (TJ) loci occludin zona occludens (ZO)-1. Confocal microscopy organized expressions proteins related to TJ...
-10-hydroxy-2-decenoic acid (10-H2DA), 10-hydroxydecanoic (10-HDAA), and sebacic (SEA) are the three major fatty acids in royal jelly (RJ). Previous studies have revealed several pharmacological activities of 10-H2DA 10-HDAA, although anti-inflammatory effects underlying mechanisms by which SEA acts poorly understood. In present study, we evaluated compared
Royal jelly (RJ), a hive product with versatile pharmacological activities, has been used as traditional functional food to prevent or treat inflammatory diseases. However, little is known about the anti-inflammatory effect of RJ in microglial cells. The aim this study assess effects lipopolysaccharide- (LPS-) induced murine immortalized BV-2 cells and explore underlying molecular mechanisms. Our results showed that LPS-stimulated cells, significantly inhibited iNOS COX-2 expression at mRNA...
Alzheimer's disease (AD) is characterized clinically by progressive cognitive decline and pathologically the accumulation of amyloid-β (Aβ) in brain. Royal jelly (RJ), a secretion honeybee hypopharyngeal mandibular glands, has previously been shown to have anti-aging neuromodulatory activities. In this study, we discovered that three months RJ treatment substantially ameliorated behavioral deficits APP/PS1 mice Morris water maze test step-down passive avoidance test. Our data also showed...
Abstract Autophagy and cellular senescence are two critical responses of mammalian cells to stress may have a direct relationship given that they respond the same set stimuli, including oxidative stress, DNA damage, telomere shortening. Mesenchymal stem (MSCs) emerged as reliable cell sources for transplantation currently being tested in numerous clinical trials. However, effects autophagy on MSC corresponding mechanisms not been fully evaluated. Several studies demonstrated level increases...
Remote sensing monitoring and geomorphologic change analysis of coral reefs are great practical significance for the ecological protection sustainable development reef area resources. A WBMD scheme is proposed to better extract information from island environments Xisha, China. Satellite imagery, after preprocessing, subjected water depth correction mitigate influence on reflectance. maximum likelihood classification model then used geomorphological classification, followed by refinement...
Neurological disorders pose significant global health challenges due to their complex etiology and insufficient understanding of underlying mechanisms. Signal transduction pathways are critical in the pathophysiology these diseases have been extensively studied develop therapeutic interventions. However, existing databases for biological signal often overlook dynamic interactions between entities within lack standardized representations signaling processes. To address limitations, we present...
In Asia, honey is mainly produced by Apis mellifera and cerana. However, the price of A. cerana usually much higher than honey. Seeing considerable profits, some dishonest companies beekeepers mislabel as or incorporate into present study, we developed methods to discriminate from based on MRJP2 (major royal jelly protein 2) gene. Two pairs species-specific primers were designed. The amplification products 212 560 bp, respectively. As little one percent incorporation in mixture can be...
Nonalcoholic fatty liver disease (NAFLD) has a high incidence in postmenopausal women and is accompanied by insulin resistance, obesity, dyslipidemia. Royal jelly (RJ), natural substance derived from hive, possesses numerous health-beneficial properties. Here, we evaluated the effects of RJ (150, 300, 450 mg kg–1 day–1, 8 weeks) on NAFLD ovariectomized (OVX) rats. Based results, ameliorated degree anxiety, improved serum lipid profile, attenuated hepatic steatosis injury OVX Furthermore,...
Chinese propolis (CP) is known as a health food but its beneficial effects in protecting cardiomyocytes remain elusive. Here, we investigated the of CP and active compounds on hydrogen peroxide (H2O2) induced rats (H9c2) oxidative injury. Cell viability decreases by H2O2 were mitigated different extracts using various solvents. From these fractions, six separated identified. Among tested isolated compound, cytoprotective activities three caffeates, caffeic acid phenethyl ester (CAPE), benzyl...
Immunosenescence comprises a set of dynamic changes occurring in innate and adaptive immune systems, macrophage aging plays an important role immunosenescence. However, function polarization macrophages have not been fully evaluated, no effective method for delaying senescence is currently available. The results this study reveal that D-galactose (D-gal) can promote J774A.1 induce M1 differentiation. Bifidobacterium lactis BB-12 significantly inhibit induced by D-gal. IL-6 IL-12 levels the...
The main purpose of this study was to analyze the structural properties and anti-inflammatory activity purified fractions derived from UV/H2O2-degraded polysaccharides Sargassum fusiforme. Results indicated that twofractions with different monosaccharide compositions morphological characteristics, PT-0.25 (yield 39.5%) PT-0.5 23.9%), were obtained. average molecular weights 14.52 kDa 22.89 kDa, respectively. In addition, exhibited better a clear dose dependence. mechanism associated...
The dinoflagellate Noctiluca scintillans is a globally distributed bloom-forming species. Previous studies have shown that the primary reason for frequent occurrence of N. blooms may be proliferation microalgae due to eutrophication, which provides sufficient source food. Meanwhile, release nutrients into environment, thus affecting population dynamics microalgae. Thus, investigate interaction between and co-occurring microalgae, this study examined their with three representative species in...
We propose a framework for probabilistic forecasting of dynamical systems based on generative modeling. Given observations the system state over time, we formulate problem as sampling from conditional distribution future given its current state. To this end, leverage stochastic interpolants, which facilitates construction model between an arbitrary base and target. design fictitious, non-physical dynamics that takes initial condition produces output sample target in finite time without bias....
Betaine/ascorbyl glucoside (Bet/AA-2G) deep eutectic solvents (DES) composed of betaine and ascorbyl had been successfully used to improve the solubility silymarin in this study. Under appropriate conditions, the...
We investigate the cross-sectional factors of Chinese corporate bond returns via reduced-rank regression analysis (RRA) proposed by He et al. (2022). collect 37 individual characteristics in extant literature using a new dataset and construct 40 factor portfolios. Empirically, we find that four-factor models created RRA outperform traditional models, PCA, PLS both in-sample out-of-sample. Among factors, market is most substantial predictor future returns. In contrast, other provide limited...