A5101623461- Advanced X-ray Imaging Techniques
- Advanced X-ray and CT Imaging
- Escherichia coli research studies
- Phosphorus and nutrient management
- Adsorption and biosorption for pollutant removal
- X-ray Spectroscopy and Fluorescence Analysis
- Microbial Community Ecology and Physiology
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Biochemical and Molecular Research
- Marine Toxins and Detection Methods
- Agricultural Engineering and Mechanization
- Digital Holography and Microscopy
- Medical Imaging Techniques and Applications
- Soil Mechanics and Vehicle Dynamics
- Constructed Wetlands for Wastewater Treatment
- Antibiotic Resistance in Bacteria
- Marine and coastal ecosystems
- Algal biology and biofuel production
- Crystallography and Radiation Phenomena
- Viral gastroenteritis research and epidemiology
- Microbial Metabolic Engineering and Bioproduction
- Protist diversity and phylogeny
- Optical measurement and interference techniques
- Metallurgical Processes and Thermodynamics
Nanjing University of Information Science and Technology
2025
Ministry of Natural Resources
2025
Microbiology Institute of Shaanxi
2023-2024
Institute of Microbiology
2022-2024
Chinese Academy of Sciences
2006-2024
Xi'an Jiaotong University
2023-2024
Chinese Academy of Agricultural Mechanization Sciences
2023-2024
State Key Laboratory of Electrical Insulation and Power Equipment
2023-2024
Inner Mongolia Agricultural University
2022-2024
Center for High Pressure Science and Technology Advanced Research
2014-2024
As a fundamental property of material, density is controlled by the interatomic distances and packing microscopic constituents. The most prominent atomistic feature in metallic glass (MG) that can be measured its principal diffraction peak position (q1) observable x-ray, electron, or neutron diffraction, which closely associated with average distance first shell. Density (and volume) would naturally expected to vary under compression proportion cube one-dimensional distance. However, using...
The large intestinal pathogen enterohemorrhagic Escherichia coli (EHEC) O157:H7 detects host cues to regulate virulence gene expression during colonization and infection. However, regulatory mechanisms of EHEC in the human intestine are not fully understood. Herein, we identified a virulence-regulating pathway where PhoQ/PhoP two-component system senses low magnesium levels signals O island 119-encoded Z4267 (LmiA; magnesium-induced regulator A), directly activating loci enterocyte...
Earth's near space is an extreme atmosphere environment with high levels of radiation, low atmospheric pressure and dramatic temperature fluctuations. The region above the flight altitude aircraft but below orbit satellites, which has special Mars-like conditions for investigating survival evolution life. Technical limitations including devices, payloads technologies/methodologies hinder microbiological research in space. In this study, we investigated microbial adaptive strategies using a...
Citrobacter species are opportunistic bacterial pathogens that have been implicated in both nosocomial and community-acquired infections. Among the genus Citrobacter, koseri is often isolated from clinical material, has known to cause meningitis brain abscess neonates immunocompromised individuals. The virulence determinants of however, remain largely unknown. Based on traditional methods, divided into 11 species, but this problematic. Here, we determined an improved, fine scale, more...
Abstract The melting temperature ( T m ) of iron at megabar pressures constrains the Earth's core structure and dynamics. Previous experimental studies demonstrated large discrepancies in high pressures. We used intrinsic resistance discontinuity across solid‐liquid transition as a criterion to study behavior laser‐heated diamond anvil cells. jump is sensitive incipient melting, capable detecting emergence less than 2 vol.% melts. found curve 30–135 GPa, but relatively low‐transition...
Abstract Background Enterohemorrhagic Escherichia coli O157:H7 (EHEC O157) causes bloody diarrhea and hemolytic-uremic syndrome. EHEC O157 encounters varied microenvironments during infection, can efficiently adapt to these using the two-component system (TCS). Recently, a functional TCS, RstAB, has been implicated in regulation of virulence several bacterial pathogens. However, regulatory function RstAB is poorly understood. This study aimed at providing insights into global effects RstA on...
The reprogrammed amino acid metabolism maintains the powerful antioxidant defense and DNA damage repair capacity of cancer cells, which could promote their escape from reactive oxygen species (ROS)-induced inevitably diminish efficacy ROS-based therapies. Herein, we propose a strategy to enhance effect chemodynamic therapy (CDT) via glutaminolysis-targeted inhibition for cells dependent on abnormal glutamine metabolism. To screen optimum drugs targeting metabolism, transcriptomic analysis is...
Abstract Background Purine nucleosides play essential roles in cellular physiological processes and have a wide range of applications the fields antitumor/antiviral drugs food. However, microbial overproduction purine by de novo metabolic engineering remains great challenge due to their strict complex regulatory machinery involved biosynthetic pathways. Results In this study, we designed an silico-guided strategy for overproducing based on genome-scale network model Bacillus subtilis . The...
Harmful algae blooms (HABs) have increased in intensity and frequency worldwide, causing negative effects on public health marine ecosystems. This study isolated identified the bloom species its associated algicidal bacterium during a phytoplankton coastal waters of Lianyungang, China. Morphological observations DNA barcoding analysis indicate that studied was caused by raphidophyte Heterosigma akashiwo, bacterium, strain LD-B1, as belonging to genus Pseudoalteromonas. Furthermore, LD-B1...
Mixed-halide perovskites have attracted extensive interest with their broadly tunable bandgap and optoelectronic properties, which makes them ideal candidates for various solar cells light-emitting diodes. However, the mixed-halide often encounter phase separation degradation under light illumination, prevents from many applications. The study on underlying mechanism controlling of is crucial to improve tailored properties practical Here, we report our systematical investigations...
Based on pinhole imaging and conventional x-ray projection imaging, a more general DEI (diffraction enhanced imaging) equation is derived using simple concepts in this paper. Not only can the new explain all same problems as with proposed by Chapman, but also some that cannot be explained old equation, such noise background caused small angle scattering diffracted analyser.
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 (O157) is a major foodborne pathogen that causes severe illness in humans worldwide. The genome of O157 contains 177 genomic islands known as O (OIs), including Shiga toxin-converting phages (OI-45 and OI-93) the locus for enterocyte effacement (LEE) pathogenicity island (OI-148). However, most genes OIs are uncharacterized code unknown functions. In this study, we demonstrated, first time, OI-9 encodes novel transcriptional activator, Z0346...
The dinoflagellate Noctiluca scintillans is a harmful algal species that globally distributed and poses certain threat to marine ecosystems. Recent research has shown the application of algicidal bacteria promising method prevent control such blooms (HABs), given its advantages safety efficiency. In this study, strain bacterium LD-B6 with high efficiency against N. was isolated from coastal waters Lianyungang, China. 16S rDNA sequence analysis showed belongs genus Pseudoalteromonas....
To accurately simulate the interactions between plug seedlings and planter during planting process explore damage mechanism of seedling substrate block, bonding parameters block were calibrated by discrete element method. The physical puncture test showed that average maximum force cone indenter on measured texture analyzer was 4.633 N. A Hertz-Mindlin with model established for in EDEM software. virtual calibration experiment designed as evaluation index. two-level factorial steepest...
The advancement in technology has changed the workflow and role of human translator recent years. impact from trend technology-mediated translation prompted ratification literacy as a major competence for modern translators. Consequently, teaching including but not limited to Computer-aided Translation (CAT) Machine (MT) became part comprehensive curricula training programs. However, many institutions, was haunted by issues such as: narrow scope curriculum design, outdated technologies,...
The computed tomography technique cannot easily be extended to diffraction enhanced imaging (DEI) because, while from DEI we may extract the refractive index gradient in one dimension, conventional CT reconstruction algorithm reconstruct only a scalar quantity. However, recently showed that changing direction of scan axis, and collecting set data related three-dimensional distribution sample, image was obtained. used is based on but with specific pre-processing projection data. mathematical...
The human intestinal pathogen enterohemorrhagic Escherichia coli (EHEC) O157:H7 causes bloody diarrhea, hemorrhagic colitis, and fatal hemolytic uremic syndrome. Its genome contains 177 unique O islands (OIs), which contribute largely to the high virulence pathogenicity although most OI genes remain uncharacterized. In current study, we demonstrated that OI-19 is required for EHEC adherence host cells. Z0442 (OI-encoded regulator A [OvrA]) encoded in positively regulated bacterial by...