A5012586602- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Cyclization and Aryne Chemistry
- Enzyme Catalysis and Immobilization
- Graphene and Nanomaterials Applications
- Bioactive Compounds and Antitumor Agents
- Gold and Silver Nanoparticles Synthesis and Applications
- Epigenetics and DNA Methylation
- Quantum Dots Synthesis And Properties
- Heme Oxygenase-1 and Carbon Monoxide
- Chalcogenide Semiconductor Thin Films
- Cancer, Hypoxia, and Metabolism
- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Synthesis of Indole Derivatives
- Carbon and Quantum Dots Applications
- Nanocluster Synthesis and Applications
- Immune cells in cancer
- Catalytic Alkyne Reactions
- Moringa oleifera research and applications
- Photoacoustic and Ultrasonic Imaging
- RNA modifications and cancer
- Peptidase Inhibition and Analysis
- Chemical Reactions and Mechanisms
- Biochemical and Structural Characterization
Jiangxi Science and Technology Normal University
2024
Jiangxi University of Traditional Chinese Medicine
2024
Chinese Academy of Sciences
2017-2022
Institute of Microbiology
2022
University of Chinese Academy of Sciences
2022
Changchun Institute of Applied Chemistry
2017-2021
Jilin University
2015-2020
Shihezi University
2017-2018
Xinjiang Production and Construction Corps
2017-2018
Abstract Bismuth sulfide (Bi 2 S 3 ) nanomaterials are emerging as a promising theranostic platform for computed tomography imaging and photothermal therapy of cancer. Herein, the properties Bi nanorods (NRs) were unveiled to intensely correlate their intrinsic deep‐level defects (DLDs) that potentially could work electron–hole nonradiative recombination centers promote phonon production, ultimately leading performance. ‐Au heterojunction NRs designed hold more significant DLD properties,...
Gold (Au) core@void@copper sulfide (CuS) shell (Au–CuS) yolk–shell nanoparticles (YSNPs) were prepared in the present study for potential chemo-, photothermal, and photodynamic combination therapy, so-called "chemophototherapy". The resonance energy transfer (RET) process was utilized Au–CuS YSNPs to achieve both enhanced photothermal performance compared with those of CuS hollow (HNPs). A series Au nanomaterials as cores that had different localized surface plasmon (LSPR) absorption peaks...
Wound healing is a complex and sequential biological process that involves multiple stages. Although various nanomaterials are applied to accelerate the wound process, only single stage promoted during lacking hierarchical stimulation. Herein, hollow CeO2 nanoparticles (NPs) with rough surface l-arginine inside (Ah NPs) developed as compact programmable nanosystem for sequentially promoting hemostasis, inflammation, proliferation The of Ah NPs works nanobridge rapidly closure wounds,...
Nitric oxide (NO) molecular messenger can reverse the multidrug resistance (MDR) effect of cancer cells through reducing P-glycoprotein (P-gp) expression, beneficial for creating a favorable microenvironment treatment doxorubicin (Dox)-resistant cells. Development sophisticated nanosystems to programmably release NO and Dox becomes an efficient strategy overcome MDR obstacles achieve promising therapeutic effects in Dox-resistant cancer. Herein, stimulated nanosystem was designed engineer...
The {101}–{001} surface heterojunction constructed on polyhedral titanium dioxide (TiO2) nanocrystals has recently been proposed to be favorable for the efficient electron–hole spatial separation due preferential accumulation of electron and hole {101} {001} facets, respectively. formed free can promote reactive oxygen species (ROS) production, which potentially used inactivation bacteria. In present study, a series truncated octahedral bipyramid TiO2 (T1, T2, T3, T4) coexposed with facets...
Silver (Ag)-based nanoparticles (NPs) with a high potential of Ag+ release have been known to be capable promoting bacteria inactivation and the wound healing process; however, keeping steady flux levels in Ag-based NPs is still challenging. Herein, novel strategy terms altering intrinsic electronic structure Ag was attempted facilitate oxidation boost flux, as results improved antibacterial performance NPs. Gold (Au), platinum (Pt), palladium (Pd) were doped into tune their d band centers...
The development of sophisticated theranostic systems for simultaneous near infrared (NIR) fluorescence imaging and phototherapy is particular interest. Herein, anisotropic plasmonic metal heterostructures, Pt end-deposited Au nanorods (PEA NRs), are developed to efficiently produce hot electrons under 808 nm laser irradiation, exhibiting the strong electric density. These can release heat through electron-phonon relaxation form reactive oxygen species chemical transformation, as a result...
Wound healing is a dynamic, interactive, and complex process, including multiple stages. Although various nanomaterials are applied to accelerate the wound process through exhibiting antibacterial activity or promoting cell proliferation, only single stage promoted during lowering efficacy. It necessary develop programmable nanosystems for stages in sequence. Herein, arginine-loaded detachable ceria-graphene nanocomposites (ACG NCs) were designed achieve this purpose. Ceria NPs graphene...
Formylglycine-generating enzymes can selectively recognize and oxidize cysteine residues within the sulfatase sub motif at terminus of proteins to form aldehyde-bearing formylglycine (FGly) residues, are normally used in protein labeling. In this study, an aldehyde tag was introduced using formylglycine-generating encoded by a reconstructed set pET28a plasmid system for enzyme immobilization. The haloacid dehalogenase ST2570 from Sulfolobus tokodaii as model enzyme. C-terminal...
The reprogrammed amino acid metabolism maintains the powerful antioxidant defense and DNA damage repair capacity of cancer cells, which could promote their escape from reactive oxygen species (ROS)-induced inevitably diminish efficacy ROS-based therapies. Herein, we propose a strategy to enhance effect chemodynamic therapy (CDT) via glutaminolysis-targeted inhibition for cells dependent on abnormal glutamine metabolism. To screen optimum drugs targeting metabolism, transcriptomic analysis is...
Abstract Bismuth sulfide (Bi 2 S 3 ) nanomaterials are emerging as a promising theranostic platform for computed tomography imaging and photothermal therapy of cancer. Herein, the properties Bi nanorods (NRs) were unveiled to intensely correlate their intrinsic deep‐level defects (DLDs) that potentially could work electron–hole nonradiative recombination centers promote phonon production, ultimately leading performance. ‐Au heterojunction NRs designed hold more significant DLD properties,...
In recent years, the development and application of site-specific immobilization technology for proteins have undergone significant advances, which avoids unwanted random covalent linkage between support active site protein in immobilization. Formylglycine generating enzyme (FGE) can transform cysteine from a conversed 6-amino-acid sequence CXPXR into formylglycine with an aldehyde group (also termed as “aldehyde tag”). Based on frame pET-28a, His-tags were replaced tags. Afterward, set...