A5027188015- Nanoplatforms for cancer theranostics
- Orbital Angular Momentum in Optics
- Microfluidic and Bio-sensing Technologies
- Laser-Ablation Synthesis of Nanoparticles
- Photodynamic Therapy Research Studies
- Immunotherapy and Immune Responses
- Gold and Silver Nanoparticles Synthesis and Applications
- Particle Dynamics in Fluid Flows
- Digital Holography and Microscopy
- Laser Material Processing Techniques
- Extracellular vesicles in disease
- Micro and Nano Robotics
- Electrowetting and Microfluidic Technologies
- Laser Applications in Dentistry and Medicine
- Cancer Immunotherapy and Biomarkers
- Ultrasound and Cavitation Phenomena
- Electrohydrodynamics and Fluid Dynamics
- Field-Flow Fractionation Techniques
- Laser-induced spectroscopy and plasma
- Cold Atom Physics and Bose-Einstein Condensates
- Antifungal resistance and susceptibility
- Ocular Infections and Treatments
- Nail Diseases and Treatments
- Photoacoustic and Ultrasonic Imaging
The University of Texas at Austin
2018-2021
National Institute of Astrophysics, Optics and Electronics
2012-2019
Universidad de Sonora
2010
In this work we demonstrate optical trapping and manipulation of microparticles suspended in water due to laser-induced convection currents. Convection currents are generated laser light absorption an hydrogenated amorphous silicon (a:Si-H) thin film. The particles dragged towards the beam's center by (Stokes drag force) allowing with powers as low 0.8 mW. However, for >3 mW trapped form a ring around beam two competing forces: Stokes thermo-photophoretic forces. Additionally, show that...
The generation and manipulation of microbubbles by means temperature gradients induced low power laser radiation is presented. A beam (λ = 1064 nm) divided into two equal parts coupled to multimode optical fibers. opposite ends each fiber are aligned separated a distance D within an ethanol solution. Previously, silver nanoparticles were photo deposited on the fibers ends. Light absorption at produces thermal gradient capable generating microbubble end in non-absorbent liquids. theoretical...
Recent focus on cancer immunotherapies has led to significant interest in the development of therapeutic strategies that can lead immunogenic cell death (ICD), which cause activation an immune response against tumor cells and improve immunotherapy outcomes by enhancing immunogenicity microenvironment. In this work, a nanomedicine-mediated combination therapy is used deliver ICD inducers doxorubicin (Dox), chemotherapeutic agent, indocyanine green (ICG), photothermal agent. These agents are...
Laser nanobubbles induce dendritic cell activation in breast cancer cells.
Abstract Background and objectives: Antimicrobial photodynamic therapy (aPDT) is a technique that combines the photoactivation properties of an innocuous chromophore or photosensitizer (PS) light, producing reactive oxygen molecules trigger cell death processes. In this study in-vitro application aPDT to fight fungal infections was investigated using methylene blue (MB) as PS. Materials methods: The antimicrobial PDT process carried out with MB red laser light (λ=633 nm) activate Testing...
Novel results are presented on thermocavitation in highly absorbing solutions using CW low power laser (λ=975 nm). Due to the large absorption coefficient (135 cm-1) at laser wavelength, penetration length is only ~74μm inside liquid and asymmetric bubbles generated near the beam's entrance wall. We report temporal dynamic of cavitation bubble, which much shorter than previously reported. found that amplitude shock wave decreases exponentially with the beam power. As shown this work, a...
Trapping with evanescent fields has become an important tool in many research fields. Evanescent allow trapping of particles close proximity to a surface. However, excitation these waves may be cumbersome. Recently, photorefractive electric been demonstrated using dielectric and metallic nano microparticles. Excitation is straight forward and, principle, can excited microwatt power level. In this work, we give comparison plasmonic emphasizing its advantages disadvantages. We show that single...
We show that trapping and manipulation of microparticles can be achieved by Rayleigh convection currents using a low power lasers. Light absorbed thin film amorphous silicon (a:Si) creates the currents. In contrast to previous works, we multiple solid without creation vapor bubbles. For (~1 mW), particles are trapped at center beam, however higher powers (~3 mW) on ring around beam due two competing forces: Stokes thermophoretic forces. Numerical simulations confirm thermal gradients...
In this work we demonstrate the increasing of trap stiffness (spring constant) constant an optical particles suspended in water by laser-induced convection currents. These currents are result thermal gradients created a light absorption thin layer hydrogenated amorphous silicon (a:Si-H) deposited at bottom cell. Since (and therefore drag forces) symmetric around beam focus trapped further contained. Around force is directed upwards and partially compensated radiation pressure depending on...
The aim of this study was to compare the effectiveness Rose Bengal (RB) and Methylene Blue (MB) as photosensitizers (PS) in Photodynamic Inactivation (PDI) on planktonic cultures <i>Candida albicans</i>, a well-known opportunistic pathogen. RB MB at concentrations ranging from 0.5 60 μM fluences 10, 30, 45 J/cm<sup>2</sup> were tested. light sources consist an array 12 led diodes with 30 mW optical power each; 490-540 nm (green light) activate 600 -650 (red MB. We first optimize <i>in...
Generation and 3D manipulation of microbubbles by means temperature gradients induced low power laser radiation is presented. Photodeposited silver nanoparticles on the distal end two optical fibers act as thermal sources after light absorption. The rises above liquid evaporation generating a microbubble at in non-absorbent liquids. Alternatively, switching between fibers, it possible to generate forces opposite directions, causing migration from one fiber optic tip another. Marangoni force...