A5009017309- Gallbladder and Bile Duct Disorders
- Urological Disorders and Treatments
- Neuroendocrine Tumor Research Advances
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Biliary and Gastrointestinal Fistulas
- Lung Cancer Research Studies
- Urinary and Genital Oncology Studies
- Intracranial Aneurysms: Treatment and Complications
- Esophageal and GI Pathology
- Neuroblastoma Research and Treatments
- Bladder and Urothelial Cancer Treatments
- Renal Transplantation Outcomes and Treatments
- Pancreatitis Pathology and Treatment
- Liver Diseases and Immunity
- Blood Coagulation and Thrombosis Mechanisms
- Antibiotic Resistance in Bacteria
- Intracerebral and Subarachnoid Hemorrhage Research
- Neutropenia and Cancer Infections
- Intraperitoneal and Appendiceal Malignancies
- Drug Transport and Resistance Mechanisms
- Vascular Procedures and Complications
- Trigeminal Neuralgia and Treatments
- Adolescent and Pediatric Healthcare
Chongqing Medical University
2020-2025
Baise University
2025
Zhejiang Cancer Hospital
2025
Chinese Academy of Sciences
2025
Wenzhou Medical University
2025
Nanjing Medical University
2025
Jiangsu Province Hospital
2025
Children's Hospital of Chongqing Medical University
2025
Chengdu University of Traditional Chinese Medicine
2024
Third Affiliated Hospital of Sun Yat-sen University
2024
Purpose: Obesity is currently a major global public health issue. It has been shown by many that gut microbiota and microbial factors regulate the pathogenesis of obesity metabolic abnormalities, but little known about their roles in different degrees obesity. Here, we sought to investigate signatures various severities. Patients Methods: We did this characterizing intestinal microbiome signature Chinese cohort obese patients healthy controls using 16S rRNA gene sequencing. To end, was...
A case of spontaneous bilateral internal carotid artery dissection (ICAD) in a 36-year-old male, potentially linked to COVID-19, is reported. Initially presenting with excessive daytime sleepiness, an atypical symptom for ICAD, the patient lacked focal neurologic deficits. Diagnostic evaluation revealed severe stenosis and dissecting aneurysms both arteries. Treatment included anticoagulation, corticosteroid therapy, subsequent endovascular stent placement. This underscores importance...
Multiple members of the caveolae-associated protein (Cavin) family are implicated in angiogenesis. However, specific role CAVIN3 pathological angiogenesis within eye remains unclear. The present study demonstrated that knockdown endothelial cells (ECs) promoted vascular normalization ocular neovascularization. Elevated expression was observed ECs retinal pigment epithelium/choroid complexes from patients with neovascular age-related macular degeneration and fibrovascular membranes...
Importance Both tacrolimus (TAC) and mycophenolate mofetil (MMF) are recommended for children with frequently relapsing nephrotic syndrome (FRNS) or steroid-dependent (SDNS). However, their comparative effectiveness safety have not been evaluated through randomized clinical trials. Objective To compare the of TAC MMF in FRNS SDNS. Design, Setting, Participants In this multicenter, open-label trial conducted at 12 pediatric nephrology centers across China, 270 aged 2 to 18 years SDNS were...
Postoperative adjuvant chemotherapy is known to enhance cure rates and thus recommended for stages pII pIII. However, specific guidelines such treatment in elderly gastric cancer (GC) patients are currently lacking. This study examines the impact of on postoperative survival these patients. We reviewed a total 7749 with GC who underwent radical gastrectomy at Zhejiang Cancer Hospital Fujian from January 2007 December 2019. conducted univariate multivariate Cox regression analyses investigate...
Abstract Application of the Caprini risk assessment model was explored in patients with deep vein thrombosis (DVT) after laparoscopic colorectal cancer surgery. This study a prospective study. The factors for DVT were assessed survey at baseline and on morning surgery, first day surgery sixth by using repeated blood vessels color Doppler ultrasound lower limbs, intraoperative postoperative conditions recorded. Among 148 surgical patients, 24.3% had asymptomatic DVT. According to...
Objective To investigate whether prior cholecystectomy is associated with incident osteoporosis. Background Cholecystectomy may have consequences involving abnormal metabolism. Studies investigating the association between and osteoporosis yielded inconsistent results. Methods In total, 17,603 UK Biobank participants underwent cholecystectomy, 35,206 matched controls were included in this study. They followed up for osteoporosis, which was determined using ICD-10 codes (M80–82). The assessed...
Hepatolithiasis is highly prevalent in East Asia characterized by the presence of gallstones biliary ducts liver. Surgical resection potentially curative treatment but bears a high risk stone recurrence and restenosis. This closely related to universal chronic proliferative cholangitis (CPC) majority patients. Recent evidence has indicated association bacterial infection with development CPC hepatolithiasis. Thus, this study aims investigate feasibility efficacy local infusion gentamicin (an...
Abstract Objective Targeting HER2 has significantly improved Overall Survival (OS) for breast cancer (BC) patients. Trastuzumab, a pivotal first-line BC drug, transformed patient outcomes, and the introduction of trastuzumab deruxtecan (T-DXd) provided an additional source hope patients with BC. The aim this meta-analysis is to comprehensively appraise clinical effectiveness safety aspects T-DXd in Methods Electronic databases, including PubMed, Web Science, Embase, Cochrane Library, were...
Background: Breast cancer diagnosis relies on accurate lesion segmentation in medical images. Automated computer-aided reduces clinician workload and improves efficiency, but existing image methods face challenges model performance generalization. Objective: This study aims to develop a generative framework using denoising diffusion for efficient breast Methods: We design novel framework, PalScDiff, that leverages probabilistic reconstruct the label distribution images, thereby enabling...
To investigate the effect of Chaihu Guizhi Decoction (CHGZD) combined with capecitabine on growth and apoptosis subcutaneous triple-negative breast cancer xenografts in nude mice explore possible mechanism.Nude mouse models bearing were randomized into 6 groups (n=10) for treatment distilled water (model group), low (10.62 g/kg), medium (21.23 g/kg) high (42.46 doses CHGZD, (0.2 mg/kg), or combination CHGZD mg/k) once daily 21 consecutive days. The general condition was observed, after...
Gastric mixed adenoneuroendocrine carcinomas (G-MANEC) are rare malignancies with about 40 cases reported to date in English literature. Clinically, G-MANEC is characterized by aggressive behavior rapid progression including a high incidence of regional and distant metastasis, leading tumor-related death without any chance surgical resection. Moreover, there no uniform standard adjuvant chemotherapy for G-MANEC. Here, we report case extensive liver metastases that gained survival benefits...