A5079979291- Clinical Laboratory Practices and Quality Control
- Meta-analysis and systematic reviews
- Healthcare cost, quality, practices
- Reliability and Agreement in Measurement
- Hemodynamic Monitoring and Therapy
- Social Sciences and Policies
- Statistical Methods in Clinical Trials
- Sepsis Diagnosis and Treatment
- Libraries, Manuscripts, and Books
- Photographic and Visual Arts
- Parathyroid Disorders and Treatments
- COVID-19 Clinical Research Studies
- Acute Kidney Injury Research
- Clinical Reasoning and Diagnostic Skills
- Patient Safety and Medication Errors
- Blood transfusion and management
- Bacterial Identification and Susceptibility Testing
- Magnesium in Health and Disease
- Galician and Iberian cultural studies
- Renal function and acid-base balance
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Archaeological and Historical Studies
- Blood groups and transfusion
- Diabetes and associated disorders
- Amino Acid Enzymes and Metabolism
Hospital Universitari Arnau de Vilanova
2011-2024
Biomedical Research Institute of Lleida
2009-2024
Azienda Ospedaliera di Padova
2022
University of Padua
2022
Walter de Gruyter (Germany)
2022
Universitat de Lleida
2017-2021
National Patient Safety Foundation
2019
Hospital Arnau de Vilanova
2007-2016
Local inflammation is thought to contribute the progression of diabetic nephropathy. The vitamin D receptor (VDR) activator paricalcitol has an antiproteinuric effect in human nephropathy at high doses. We have explored potential anti-inflammatory effects VDR doses that do not modulate proteinuria experimental model gain insights into benefits activators those patients whose decreased by this therapy. calcitriol and on renal function, albuminuria, was a rat diabetes induced streptozotocin....
Quality indicators (QIs) are fundamental tools for enabling users to quantify the quality of all operational processes by comparing it against a defined criterion. QIs data should be collected over time identify, correct, and continuously monitor defects improve performance patient safety identifying implementing effective interventions. According international standard medical laboratories accreditation, laboratory shall establish periodically review evaluate throughout critical aspects...
Laboratory diagnostics develop through different phases that span from test ordering (pre-preanalytical phase), collection of diagnostic specimens (preanalytical sample analysis (analytical results reporting (postanalytical phase) and interpretation (post-postanalytical phase). Although laboratory medicine seems less vulnerable than other clinical areas, the chance errors is not negligible may adversely impact on quality testing patient safety. This article, which continues a biennial...
Abstract It has been well reported over recent years that most errors within the total testing process occur in pre-analytical phase (46%–68.2%), an area is usually outside of direct control laboratory and which includes sample collection (phlebotomy). National international (WHO, CLSI) guidelines recommend order draw blood during phlebotomy should be culture/sterile tubes, then plain tubes/gel tubes containing additives. This prevents contamination with additives from previous could cause...
Venous blood sampling (phlebotomy) is the most common invasive procedure performed in patient care. Guidelines on correct practice of phlebotomy are available, including H3-A6 guideline issued by Clinical Laboratory Standards Institute (CLSI). As quality practices and procedures related to venous sample collection European countries was unknown, Federation Chemistry Medicine (EFLM) Working Group for Preanalytical Phase conducted an observational study 12 countries. The demonstrated that...
Background: The aim of this study was to identify process indicators for the three phases laboratory activity and their corresponding quality specifications in our setting (primary care centers, second- third-level hospitals that provide public healthcare services Catalonia).
The results of 5 years experience (2004-2008) with process-based quality management using indicators for key laboratory processes (analytic and extra-analytic) in a group clinical laboratories affiliated the Catalan Health Institute are presented. Our purpose was to analyze evolution indicators, identify that require corrective measures, obtain specifications more robust than preliminary ones proposed previous study by same group.The yearly average recorded each indicator laboratory,...
No guideline currently exists on how to detect or document haemolysis, icterus lipemia (HIL) in blood samples, nor subsequent use of this information. The EFLM WG-PRE has performed a survey for assessing current practices European laboratories HIL monitoring. This second part two coherent articles is focused HIL.An online survey, containing 39 questions preanalytical issues, was disseminated among member countries. Seventeen exclusively assessment, management and follow-up actions routine...
CRP is elevated in patients with acute exacerbations of COPD (AECOPD), but there little information on whether this biomarker can help to identify adverse short-term clinical outcomes.A 6-month prospective study all AECOPD requiring hospital admission. Clinical, laboratory (including plasma levels at admission) and functional data were recorded. The outcome variable (the outcome) consisted of: (i) death or within 15 days discharge, (ii) transfer the intensive care unit, (iii) development...
Abstract Hemolysis is the main cause of non-quality samples in clinical laboratories, producing highest percentage rejections external assurance programs preanalytical quality. The objective was to: 1) study agreement between detection methods and quantification hemolysis; 2) establish comparable hemolysis interference limits for a series tests analytical methods; 3) variables which most influence production. Different hemoglobin concentration standards were prepared using reference method....
Compared to other activities of the testing process, preanalytical phase is plagued by a lower degree standardization, which makes it more vulnerable errors. With aim providing guidelines and recommendations, EFLM WG-PRE issued survey across European medical laboratories, gather information on local practices. This part one two coherent articles, covers all practices monitoring quality except haemolysis, icterus lipemia (HIL).An online survey, containing 39 questions dealing with broad...
Preanalytical variables, such as sample collection, handling and transport, may affect patient results. phase quality monitoring should be established in order to minimize laboratory errors improve safety.A retrospective study (2001-2013) of the results obtained through Spanish Society Clinical Biochemistry Molecular Pathology (SEQC) External assessment (preanalytical phase) was performed summarize data regarding main factors affecting preanalytical quality. Our aim compare from 2006 2013...
Abstract Background Nowadays over-the-counter (OTC) drugs and dietary supplements are widely used. Their use can have a significant impact on the validity of laboratory results. The aim this multicenter European study was to determine frequency consumption various products OTC among patients explore their level knowledge awareness about potential test Methods Eighteen countries participated in study. survey carried out anonymously subsequent series outpatients (n=200) each participating...
Classical risk factors of atherosclerosis in the general population show paradoxical effects chronic kidney disease (CKD) patients. Thus, low low-density lipoprotein (LDL) cholesterol levels have been associated with worse cardiovascular outcomes. Magnesium (Mg) is a divalent cation whose homeostasis altered CKD. Furthermore, Mg health. The present study aims to understand relationships and lipid parameters In this analysis, 1754 participants from Observatorio Nacional de Atherosclerosis en...
Abstract Since the beginning of laboratory medicine, main focus was to provide high quality analytics. Over time importance extra-analytical phases and their contribution overall became evident. However, as initial preanalytical processes take place outside mostly without its supervision, all professions participating in these process steps, from test selection sample collection transport, need engage accordingly. Focusing solely on intra-laboratory will not be sufficient achieve best...
N-methyl-d-aspartate receptors (NMDAR) are tetrameric amino acid which act as membrane calcium channels. The presence of the receptor has been detected in principal organs responsible for homeostasis (kidney and bone), pointing to a possible role mineral metabolism. In present work, was determined normal parathyroid glands (PTG) by real-time PCR, immunoprecipitation, immunohistrochemistry. Healthy animals showed decrease blood hormone (PTH) levels 15 min after treatment with NMDA. This...
Background: Verification uses logical algorithms to detect potential errors before laboratory results are released the clinician. Even though verification is one of main processes in all laboratories, there a lack standardization mainly used and criteria limits applied. A survey clinical laboratories Spain was conducted order assess process, particularly use autoverification.
This work is the second part of a study regarding indicators and quality specifications for non-analytical processes in laboratory medicine. Five primary care five hospital laboratories agreed on two strategic (quality planning project development) various support (client relationships, instrument infrastructure maintenance, safety risk prevention, purchases storage, personnel training).In majority cases, median values recorded over 1 year considered to be state-of-the-art our setting...