A5100681737- Traditional Chinese Medicine Analysis
- Alcohol Consumption and Health Effects
- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
- Drug Transport and Resistance Mechanisms
- Drug-Induced Hepatotoxicity and Protection
- Family and Patient Care in Intensive Care Units
- Natural product bioactivities and synthesis
- Cancer, Hypoxia, and Metabolism
- Advanced Glycation End Products research
- NF-κB Signaling Pathways
- Radiopharmaceutical Chemistry and Applications
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Medical Research and Treatments
- Nutrition and Health in Aging
- Traditional and Medicinal Uses of Annonaceae
- Nursing education and management
- Coaching Methods and Impact
- Lipid metabolism and biosynthesis
- Health Systems, Economic Evaluations, Quality of Life
- Medicinal Plants and Neuroprotection
- Schizophrenia research and treatment
- Sharing Economy and Platforms
Jiangxi Agricultural University
2024
Central South University
2022-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Xiyuan Hospital
2024
Shenyang Pharmaceutical University
2023
Anhui Medical University
2019-2023
China Medical University
2022-2023
Shanxi Medical University
2013-2023
Shanghai Mental Health Center
2023
Changsha Medical University
2021-2022
Due to substantial morbidity and high complications, diabetes mellitus is considered as the third "killer" in world. A search for alternative antidiabetic drugs from herbs or fungi highly demanded. Our present study aims investigate activities of Cordyceps militaris on diet-streptozotocin-induced type 2 rats. Diabetic rats were orally administered with water extract alcohol at 0.05 g/kg 3 weeks, then, factors levels related blood glucose, lipid, free radicals, even nephropathy determined....
An increasing number of interventions have focused on leadership development for healthcare managers, among which coaching is a common strategy. The purpose the present systematic review to synthesize evidence effect in developing managers.A literature search will be conducted six English databases (MEDLINE (Ovid), CINAHL, Embase, Cochrane library, Nursing & Allied Health Premium, and Scopus) four Chinese (Wanfang, CNKI, SinoMed, VIP) from inception April 1st, 2022. titles, abstracts, full...
Nursing students' internship experiences may significantly impact their caring ability. However, there is a lack of comprehensive evaluation undergraduate nursing ability pre-and post-internship in China. This study aimed to explore the differences students before and after internship.The sample comprised 305 who had undergone internships during 2018-2020 three hospitals Changsha, Caring Ability Inventory was used measure compare internship. Descriptive statistics paired t-test were employed...
Abstract Acute myeloid leukaemia is a complex, highly aggressive hematopoietic disorder. Currently, in spite of great advances radiotherapy and chemotherapy, the prognosis for AML patients with initial treatment failure still poor. Therefore, need novel efficient therapies to improve outcome has become desperately urgent. In this study, we identified expression ZEB1 (a transcription factor) focused on its possible role mechanisms progression AML. According data provided by Gene Expression...
Background Clara cell 10-kDa protein (CC10) is a multifunctional with anti-inflammatory and immunomodulatory effects. Induction of CC10 expression by gene transfection may possess potential therapeutic effect. Nuclear factor κB (NF-κB) plays key role in the inflammatory processes airway diseases. Method/Results To investigate effect controlling inflammation underlying intracellular mechanisms, this study, we constructed plasmid transfected it into bronchial epithelial line BEAS-2B cells...
Abstract Background Endotracheal suctioning is one of the most frequently performed invasive procedures by intensive care nurses. Nurses should have adequate knowledge and skills to perform endotracheal based on best evidence. Little known about nurses’ practice evidence-based in Chinese hospitals. The purpose this study was investigate recommendations regarding suctioning. Specifically, aimed examine (1) awareness adherence guidelines (2) factors influencing their level adherence. Methods A...
Early-onset Schizophrenia (EOS) is a profoundly progressive psychiatric disorder characterized by both positive and negative symptoms, whose pathogenesis influenced genes, environment brain structure development. In this study, the MIND (Morphometric Inverse Divergence) network was employed to explore relationship between morphological similarity specific transcriptional expression patterns in EOS patients. This study involved cohort of 187 participants aged 7 17 years, consisting 97...
The growth hormone receptor (GHR) gene is correlated with many phenotypic and physiological alternations in chicken, such as shorter shanks, lower body weight muscle mass loss. However, the role of GHR mitochondrial function remains unknown poultry. In this study, we assessed mitochondria sex-linked dwarf (SLD) chicken skeletal interfered expression DF-1 cells to investigate both vivo vitro. We found that key regulators biogenesis DNA (mtDNA)-encoded oxidative phosphorylation (OXPHOS) genes...
Retinal degeneration is characterized by the progressive loss of photoreceptors, and stem cell therapy has become a promising strategy. Many studies have reported that mesenchymal transplantation can sustain retinal structure prolong functions based on two mechanisms. One replacement, other paracrine action cells. Cells from human exfoliated deciduous teeth (SHEDs) show characteristics typical They are derived neural crest potential cellular source for regeneration in therapy. In this study,...
Acetaminophen (APAP) is one of the major causes drug-induced acute liver injury, and ethanol may aggravate APAP-induced injury. The problem ethanol- injury becomes increasingly prominent, but mechanism remains ambiguous. p38γ four isoforms P38 mitogen activated protein kinases, that contributes to inflammation in different diseases. In this study we investigated role Liver was induced male C57BL/6 J mice by giving liquid diet containing 5% (v/v) for 10 days, followed gavage (25% (v/v), 6...
Promoting agricultural green development is crucial for achieving modernization and ecological civilization.Based on the current status problems of in China, this study analyzes internal mechanism by which digital technology enables from four dimensions: factor allocation, industrial synergy, information sharing, feedback effects.Combined with application practices enterprises, explores logic enabling through proposes a dual-driving force mechanism: market government regulation.In terms...
Abstract Aim This study aimed to explore 1) factors that influenced the evidence‐based practice competencies and behaviors of clinical nurses 2) interaction between organizational culture, head nurses' implementation leadership, behaviors. Background The significance culture leadership in enhancing behavior is widely recognized healthcare settings. However, there limited knowledge how these influence behavior. Methods A cross‐sectional survey was conducted at 10 hospitals China. Data were...
Hollow fiber solvent bar microextraction coupled with high-performance liquid chromatography was developed for the preconcentration and determination of active ingredients in Radix Salvia miltiorrhiza. These include dihydrotanshinone I, cryptotanshinone, tanshinone IIA, salvianolic acid B, danshensu, protocatechuic aldehyde. To evaluate technique, seven compounds varying polarity were used as model analytes, a polyvinylidene fluoride hollow (1.0 cm) octanol (2 µL) bar. The extraction...
The expression levels of the synaptic-related proteins contactin 1/2 (CNTN1/2) are down-regulated in brain Alzheimer's disease (AD), but mechanism has not been clarified. γ-Aminobutyric acid (GABA) is considered a biologically active ingredient food. Our previous research revealed that GABA can regulate CEBPα Aβ-treated U251 cells. However, it uncertain whether antagonize pathogenesis AD. Whether inhibit reduction CNTN1/2 by regulating CEBPα/circAPLP2/miR-671-5p AD remains unclear yet. Here,...
To determine the concentration of gastrodigenin in tissue homogenates with high performance liquid chromatography (HPLC) , order to study changes distribution before and after combined application rat tissues, including heart, liver, spleen, lung, kidney brain tissues. The showed that could be found kidney, lungs, spleen After Gastrodiae Rhizoma Ligustici Wallichii Rhizoma, content decreased liver varying degrees, while increasing lung brain. This indicated had certain impact on vivo...