A5100386691- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Gut microbiota and health
- Monoclonal and Polyclonal Antibodies Research
- Cancer, Hypoxia, and Metabolism
- Ferroptosis and cancer prognosis
- interferon and immune responses
- Nutrition and Health in Aging
- Plant Gene Expression Analysis
- Neonatal Respiratory Health Research
- Mosquito-borne diseases and control
- Autoimmune and Inflammatory Disorders Research
- Identification and Quantification in Food
- Liver Disease Diagnosis and Treatment
- Barrier Structure and Function Studies
- Lung Cancer Treatments and Mutations
- Text and Document Classification Technologies
- Parasitic infections in humans and animals
- Mycobacterium research and diagnosis
- vaccines and immunoinformatics approaches
- Mathematics, Computing, and Information Processing
- Esophageal Cancer Research and Treatment
- Inflammatory mediators and NSAID effects
- Food composition and properties
- Colorectal Cancer Treatments and Studies
China People's Public Security University
2025
Northwest A&F University
2023-2025
Huazhong Agricultural University
2024-2025
First Hospital of Shanxi Medical University
2025
Shanxi Medical University
2025
North Sichuan Medical University
2025
Hunan University
2024
Shaanxi Normal University
2014-2024
West China Hospital of Sichuan University
2020-2024
Wuhan University
2022-2024
Anomaly detection from graph data has drawn much attention due to its practical significance in many critical applications including cybersecurity, finance, and social networks. Existing mining machine learning methods are either shallow that could not effectively capture the complex interdependency of or autoencoder fully exploit contextual information as supervision signals for effective anomaly detection. To overcome these challenges, this paper, we propose a novel method, Self-Supervised...
This study aimed to investigate the roles of long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) in osteogenic differentiation periodontal ligament stem cells (PDLSCs) periodontitis.Differentially lncRNAs and mRNAs between periodontitis tissues healthy were selected out using R project. PDLSCs identified flow cytometry. Western blot was employed detect pathway relative proteins. Besides, targeted relationships lncRNA miRNA, as well miRNA mRNA verified by dual luciferase reporter...
Introduction: The aim of this study was to investigate the prevalence and associated factors sarcopenia defined by different criteria in community-dwelling adults west China using baseline data West-China Health Aging Trend (WCHAT) study. Methods: Adults aged 50 years or older communities Yunnan, Guizhou, Sichuan, Xinjiang provinces were enrolled We applied 6 diagnostic (AWGS 2019, AWGS 2014, EWGSOP1, EWGSOP2, IWGS, FNIH) define sarcopenia. Muscle mass measured based on bioimpedance...
Abstract Tumor metastasis imposes metabolic requirements for escaping from primary tissues, producing vulnerability in treatment. This study aimed to explore the reprogramming relevant lung adenocarcinoma (LUAD) and decode underlying intercellular alterations. Using gene expression profiles of 394 LUAD samples derived The Cancer Genome Atlas (TCGA), we identified 11 metastasis-related genes involved glycolysis lipid metabolism, defined three phenotypes (MP-I, -II, -III) using unsupervised...
Abstract Japanese encephalitis virus (JEV) is a neurotropic pathogen that causes lethal encephalitis. The high susceptibility and massive proliferation of JEV in neurons lead to extensive neuronal damage inflammation within the central nervous system. Despite research on pathogenesis, effect cellular composition viral tropism towards distinct subtypes brain still not well comprehended. To address these issues, we performed single-cell RNA sequencing (scRNA-seq) cells isolated from JEV-highly...
With the ongoing challenge of air pollution posing serious health and environmental threats, particularly in rapidly industrializing regions, accurate forecasting effective pollutant identification are crucial for enhancing public ecological stability. This study aimed to optimize quality management through prediction Air Quality Index (AQI) pollutants. Our spans nine representative cities (Hohhot, Yinchuan, Lanzhou, Beijing, Taiyuan, Xi'an, Shanghai, Nanjing, Wuhan) China, with data...
Purpose: The study aimed to quantitatively evaluate the fundus tessellated density (FTD) in different categories of pathologic myopia (PM) using photographs with application artificial intelligence. Methods: A retrospective review 407 PM (META-PM, Category 2–Category 4) eyes was conducted, employing a biomimetic mechanism human vision and integrated image processing technologies for FTD extraction calculation. Different regions interest were analyzed, including circle O4.5 (optic disc...
Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology, characterized by high fever, transient cutaneous rash, arthralgia/arthritis, and leukocytosis. Liver involvement in AOSD has been described, but few reports have described it depth. The present study analyzed clinical laboratory features series Chinese patients.Data 77 patients with (fulfilling Yamaguchi's diagnostic criteria) were retrospectively reviewed compared other series.The characteristics our...
The rise of the digital economy and e-commerce has fostered a movement towards efficient low-resource medical information processing, trend that holds great importance in healthcare sector. Diabetes, being widespread chronic condition, witnessed introduction glucometers, which offer patients convenient method monitoring their blood sugar levels. However, it is worth noting considerable proportion online comments may be subject to emotional bias or contain inaccurate information. Furthermore,...
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ABSTRACT Low‐nitrogen (LN) conditions typically promote anthocyanin biosynthesis in plants. Although previous studies primarily explored structural genes and transcription factors involved biosynthesis, the role of long noncoding RNAs (lncRNAs) this process under LN remains less understood. This study identified LNC159c as a potential regulator with its expression notably downregulated conditions. functions host gene miR159c, which regulates expression. A dual‐luciferase reporter assay GFP...
This study primarily addresses the analytical problem of mathematical mechanism underlying associative impact between online searches and vaccine uptake, a relationship that has become increasingly relevant in context public health management. As internet search behaviors reflect interest sentiment, understanding their on vaccination trends is crucial for real-time decision-making. A Logistic model constructed to observe fundamental evolutionary patterns uptake. To explore mutual influence,...
Introduction Gestational diabetes mellitus (GDM) is a serious health problem that poses threats to both mothers and babies, thus leading the intensive need for management. The current study examined how SFEE diet management intervention affected glycemic control, maternal outcomes, dietary compliance in GDM. Methods Patients not enrolled were ascribed either group or control which standard advice was provided. Although assessors of outcome blind, participants providers not. principal...
Background: Claudins are a family of integral membrane proteins that critical for the formation tight junctions in epithelial and endothelial cells. Aberrant expression Claudin members is implicated progression various cancers, making them valuable biomarkers tumor diagnosis, prognosis, therapeutic targeting. such as CLDN-6, CLDN-9, splice variant CLDN-18.2. An antibody drug targeting CLDN18.2 was recently approved by FDA treatment advanced gastric cancer. Despite their clinical potential,...