A5041611656- Air Quality and Health Impacts
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Climate Change and Health Impacts
- Gestational Diabetes Research and Management
- Global Health Care Issues
- Hepatitis B Virus Studies
- Reproductive System and Pregnancy
- Thyroid Disorders and Treatments
- Obesity, Physical Activity, Diet
- Syphilis Diagnosis and Treatment
- Hepatitis C virus research
- Blood Pressure and Hypertension Studies
- Obesity and Health Practices
- Energy and Environment Impacts
- Smoking Behavior and Cessation
- Hypothalamic control of reproductive hormones
- Health disparities and outcomes
- Cardiovascular Function and Risk Factors
- Preterm Birth and Chorioamnionitis
- Hepatitis Viruses Studies and Epidemiology
- Assisted Reproductive Technology and Twin Pregnancy
- Insurance, Mortality, Demography, Risk Management
- Cardiovascular Health and Disease Prevention
- Liver Disease Diagnosis and Treatment
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025
Central South University of Forestry and Technology
2025
Central South University
2025
Tianjin Municipal Research Institute for Family Planning
2015-2024
Peking Union Medical College Hospital
2011-2024
Peking University First Hospital
2022-2024
Peking University
2022-2024
Southern Medical University
2023-2024
Anhui Jianzhu University
2024
Huazhong University of Science and Technology
2016-2024
Objectives. To estimate the percentage of excess death for US Black and White men women associated with high body mass, we examined combined effects age variation in obesity–mortality relationship cohort age-specific obesity prevalence. Methods. We 19 National Health Interview Survey waves linked to individual Death Index mortality records, 1986–2006, patterns population-level association between adult mortality. Results. The estimated deaths 1986 2006 overweight was 5.0% 15.6% men, 26.8%...
Background Diabetes mellitus (DM) increases the risk of adverse maternal and neonatal outcomes, optimization glycemic control during pregnancy can help mitigate risks associated with diabetes. However, studies seldom focus precisely on blood glucose level prior to pregnancy. We aimed evaluate associations between preconception fasting plasma (FPG) subsequent outcomes. Methods findings conducted a population-based retrospective cohort study among 6,447,339 women aged 20–49 years old who...
<h3>Importance</h3> Airborne particulate matter pollution has been associated with preterm birth (PTB) in some studies. However, most of these studies assessed only populations living near monitoring stations, and the association airborne having a median diameter 1 μm or less (PM<sub>1</sub>) PTB not studied. <h3>Objective</h3> To evaluate whether PM<sub>1</sub>concentrations are risk PTB. <h3>Design, Setting, Participants</h3> This national cohort study used National Free Preconception...
The epidemiology of valvular heart disease (VHD) has changed markedly over the last 50 years worldwide, and prevalence features VHD in China are unknown. objective this study was to investigate current status etiology China.We used a cross-sectional national survey with stratified multistage random sampling from general Chinese population estimate burden. Data on demographic characteristics, medical history, physical examination, blood tests, potential were collected. Echocardiography detect...
Abstract Impaired brain glucose metabolism is an early indicator of Alzheimer’s disease (AD); however, the fundamental mechanism unknown. In this study, we found a substantial decline in isocitrate dehydrogenase 3β (IDH3β) levels, critical tricarboxylic acid cycle enzyme, AD patients and AD-transgenic mice’s brains. Further investigations demonstrated that knockdown IDH3β induced oxidation-phosphorylation uncoupling, leading to reduced energy lactate accumulation. The resulting increased...
Abstract Obesity has been increasing worldwide. Data on obesity status among men of reproductive age are scarce. This study aimed to assess the national prevalence and trend overweight reproductive-age in rural China. In nationwide population-based study, data were obtained from National Free Preconception Health Examination Project China 2010 2014. Weight height measured 16 161 982 aged 15–49 years their female partners (15 997 739 participants years) before conception, body mass index...
Most evidences regarding ambient PM2.5 or PM10 (particulate matter of median aerodynamic diameter ≤2.5 μm ≤10 μm) and preterm birth (PTB) come from western countries which has relatively low PM pollution exposure, the results are still inconsistent. This study aims to examine whether exposure high concentrations was associated with PTB (<37 weeks) near term (37-38 weeks).We established a cohort 1,280,524 singleton pregnancies who delivered Dec 1st, 2013 Nov 30th, 2014 matched their home...
Exposure to greenness may lead a wide range of beneficial health outcomes. However, the effects on preterm birth (PTB) are inconsistent, and limited studies have focused subcategories PTB. A total 3,751,672 singleton births from national cohort in mainland China were included this study. Greenness was estimated using satellite-based Normalized Difference Vegetation Index (NDVI) Enhanced with 500-m 1,000-m buffers around participants' addresses. The PTB (20-36 weeks) extremely (EPTB, 20-27...
To provide prevalence and trends of underweight, overweight, obesity among reproductive-age women adolescent girls in rural China.We measured weight height 16 742 344 aged 20 to 49 years 178 556 15 19 from the National Free Preconception Health Examination Project between 2010 2014.Among women, underweight was 7.8% (95% confidence interval [CI] = 7.7%, 7.9%), overweight or 16.5% CI 16.4%, 16.6%; World Organization criteria). Among adolescents, 6.0% 5.7%, 6.2%; Centers for Disease Control...
To investigate the spectrum, antibiotic-resistant pattern, risk factors, and outcomes of infection in patients hospitalized with systemic lupus erythematosus (SLE).We collected clinical microbiological data from SLE between June 2005 2015, then conducted retrospective analyses.Among our sample 3815 patients, 1321 (34.6%) were diagnosed infection. The majority (78.3%) occurred within 5 years onset. Bacterial was predominant (50.6%), followed by viral (36.4%) fungal (12.5%). lungs (33.7%)...
Abstract Background The universal two-child policy in China which was announced October 2015 might affect the caesarean birth rate. Few studies reported rate affected by especially after period. This study aimed to demonstrate changes before and further elaborate underlying influencing factors. Methods nationwide, retrospective, population-based based on National Free Pre-Pregnancy Check-ups Project (NFPCP). Couples planning conceive next 6 months were encouraged participate NFPCP. Baseline...
BACKGROUNDNucleos(t)ide analog (NA) has shown limited effectiveness against hepatitis B surface antigen (HBsAg) clearance in chronic (CHB) patients. AIMTo evaluate the efficacy and safety of add-on peginterferon α-2a (peg-IFN α-2a) to an ongoing NA regimen CHB METHODSIn this observational study, 195 patients with HBsAg ≤ 1500 IU/mL, e (HBeAg)-negative (including HBeAg-negative or HBeAg-positive who achieved after antiviral treatment NA) virus-deoxyribonucleic acid < 1.0 × 102 IU/mL over 1...
Little is known about the effect of ambient temperature on preterm birth, especially for trimester-specific effects. To evaluate whether exposure to relatively low or high during pregnancy associated with increasing risk birth not. We analysed data a cohort 1,281,859 singleton pregnancies 2013–2014 and matched home address each pregnant women model based daily meteorological air pollution data. Then we used Cox proportional hazard regression models random estimate non-linear associations...
This study aims to investigate the fetal outcomes and associated factors of adverse pregnancy (APOs) in pregnant women with systemic lupus erythematosus (SLE). Clinical data from 251 SLE patients 263 pregnancies 2001 2015 were analyzed retrospectively. APOs occurred 70.0% pregnancies, which loss 28.5%; preterm delivery 21.3%; intrauterine growth retardation 12.2%; distress 8.0%. Over time, rate decreased 82.8% during 2001~2005 59.6% 2011~2015. In multivariate analysis, predictors included...
Preterm birth (PTB) was one of the leading causes neonatal death. Predicting PTB in first trimester and second will help improve pregnancy outcomes. The aim this study is to propose a prediction model based on machine learning algorithms for PTB. Data were reviewed from 2008 2018, all participants included selected hospital China. Six algorisms, including Naive Bayesian (NBM), support vector (SVM), random forest tree (RF), artificial neural networks (ANN), K-means, logistic regression, used...
With the ongoing challenge of air pollution posing serious health and environmental threats, particularly in rapidly industrializing regions, accurate forecasting effective pollutant identification are crucial for enhancing public ecological stability. This study aimed to optimize quality management through prediction Air Quality Index (AQI) pollutants. Our spans nine representative cities (Hohhot, Yinchuan, Lanzhou, Beijing, Taiyuan, Xi'an, Shanghai, Nanjing, Wuhan) China, with data...