Anda Botoseneanu

ORCID: 0000-0003-0628-5820
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About
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Research Areas
  • Chronic Disease Management Strategies
  • Health disparities and outcomes
  • Nutrition and Health in Aging
  • Health Systems, Economic Evaluations, Quality of Life
  • Obesity, Physical Activity, Diet
  • Frailty in Older Adults
  • Aging and Gerontology Research
  • Dementia and Cognitive Impairment Research
  • Physical Activity and Health
  • Diabetes Management and Education
  • Nutritional Studies and Diet
  • Healthcare Policy and Management
  • Obesity and Health Practices
  • Public Health Policies and Education
  • Medical Malpractice and Liability Issues
  • Global Health Care Issues
  • Primary Care and Health Outcomes
  • Health Promotion and Cardiovascular Prevention
  • Global Cancer Incidence and Screening
  • Birth, Development, and Health
  • Medication Adherence and Compliance
  • Balance, Gait, and Falls Prevention
  • Diet and metabolism studies
  • Bariatric Surgery and Outcomes
  • BRCA gene mutations in cancer

University of Michigan–Dearborn
2016-2025

University of Michigan
2015-2025

Michigan Department of Health and Human Services
2017-2024

Michigan United
2019-2024

Oregon Health & Science University
2021

Yale University
2012-2015

Multimorbidity-having two or more coexisting chronic conditions-is highly prevalent, costly, and disabling to older adults. Questions remain regarding diseases accumulation over time whether this differs by racial ethnic background. Answering knowledge gap, study identifies differences in rates of disease multimorbidity development among non-Hispanic white, black, Hispanic participants starting middle-age followed up 16 years.We analyzed data from the Health Retirement Study (HRS), a...

10.1371/journal.pone.0218462 article EN cc-by PLoS ONE 2019-06-17

Multimorbidity (multiple co-occurring chronic diseases) is associated with greater likelihood of disability and mortality, above beyond the risk attributable to individual diseases. This study identifies prevalent multimorbidity patterns evaluates their association among U.S. older adults. Prospective cohort using longitudinal Health Retirement Study data (2010–2012). We included 8,782 participants aged 65 years used negative binomial models examine prospective disability, measured by...

10.1093/gerona/glw035 article EN The Journals of Gerontology Series A 2016-03-11

Multimorbidity (multiple co-occurring chronic conditions) may be an important contributor to disability and poor health-related quality of life. The functional consequences specific combinations somatic mental health conditions are unclear. Nationally representative prospective cohort study using the National Health Aging Trends Study data Medicare beneficiaries. We included 4,017 participants aged 65 years or older interviewed in 2013 2014. primary outcome was activities daily living...

10.1093/gerona/glx100 article EN The Journals of Gerontology Series A 2017-05-24

This research sought to examine socioeconomic stratification in the joint trajectories of physical, emotional, and cognitive functioning among older Americans how it differs by age groups. We used data from a nationally representative sample 9,237 65 or Health Retirement Study, who were observed biennially 1998 2010. Joint characterized using group-based mixture model. then applied multinomial logistic regression analysis evaluate their linkages with status differ identified four distinct...

10.1093/geronb/gbu095 article EN The Journals of Gerontology Series B 2014-08-26

Despite documented age-related declines in self-reported functional status and measured physical capacity, it is unclear whether these indicators follow similar trajectories over time or the patterns of change differ by sex. We used longitudinal data from 687 initially nondisabled adults, aged 70 older, Precipitating Events Project, who were evaluated every 18 months for nearly 14 years. Self-reported disability was assessed with a 12-item scale. Physical capacity using grip strength...

10.1093/gerona/glw038 article EN The Journals of Gerontology Series A 2016-04-12

Few studies have focused on the relationship between trajectories of long-term changes in body mass index (BMI; weight (kg)/height (m)2) and all-cause mortality old age, particularly non-Western populations. We evaluated this association by applying group-based mixture models to data derived from National Survey Japanese Elderly, which included 4,869 adults aged 60 or more years, with up 7 repeated observations 1987 2006. Four distinct BMI were identified: "low-normal weight, decreasing"...

10.1093/aje/kwv107 article EN American Journal of Epidemiology 2015-09-12

Objectives To evaluate the prevalence of metabolic syndrome (MetS) and its association with physical capacity, disability, self‐rated health in older adults at high risk mobility including those without diabetes mellitus. Design Cross‐sectional analysis. Setting Lifestyle Interventions Independence for Elders ( LIFE ) Study. Participants Community‐dwelling sedentary aged 70 to 89 disability (Short Physical Performance Battery SPPB score ≤9; mean 7.4 ± 1.6) (N = 1,535). Measurements Metabolic...

10.1111/jgs.13205 article EN Journal of the American Geriatrics Society 2015-01-30

Advancements in Alzheimer’s disease and related dementias (ADRD) research on the U.S. population acknowledge importance of high burden ADRD segments yet-to-be characterized risks attributable to multiple chronic diseases (multimorbidity). These realizations suggest successful strategies caring for people with their caregivers will rely not only clinical treatments but also more refined comprehensive models that take its broad effects whole-person whole society into consideration. To this...

10.1177/1533317520960874 article EN cc-by-nc-nd American Journal of Alzheimer s Disease & Other Dementias® 2020-01-01

Evaluating multimorbidity combinations, racial/ethnic background, educational attainment, and sex associations with age-related cognitive changes is critical to clarifying the health, sociodemographic, socioeconomic mechanisms associated function in later life. Data from 2011–2018 National Health Aging Trends Study for respondents aged 65 years older (N = 10,548, mean age 77.5) were analyzed using linear mixed effect models. Racial/ethnic differences (mutually-exclusive groups: non-Latino...

10.1016/j.ssmph.2022.101084 article EN cc-by-nc-nd SSM - Population Health 2022-04-04

Introduction: Mexico faces unique challenges due to the confluence of population ageing, an increasing burden chronic conditions and limited resources address these concerns. Substantial evidence links both independent co-occurring risk cognitive decline, but association between common multimorbidity patterns change in function has not been examined among older adults Mexico. Objective: The objective our research was identify most ageing Mexican 2012, then examine with advancing age....

10.1332/29767202y2024d000000019 article EN Journal of global ageing. 2025-01-13

To depict the trajectory of BMI from middle to late adulthood and examine social variations in trajectories.Eight waves (1992-2006) Health Retirement Study involving a nationally representative sample Americans aged 51 61 years at baseline were used. Changes analyzed using hierarchical linear modeling with time-constant time-varying covariates.BMI increased linearly over time. Compared Caucasians, African-Americans had higher levels, while Hispanics similar but lower rates increase Higher...

10.1177/0898264310385930 article EN Journal of Aging and Health 2010-11-10
Mylène Aubertin‐Leheudre Stephen D. Anton Daniel P. Beavers Todd M. Manini Roger A. Fielding and 95 more Anne B. Newman Tim Church Stephen B. Kritchevsky David E. Conroy Mary Mcdermott Anda Botoseneanu Michelle E. Hauser Marco Pahor Thomas M. Gill Carlos A. Vaz Fragoso Roger A. Fielding Michelle E. Hauser Marco Pahor Jack M. Guralnik Christiaan Leeuwenburgh Connie Caudle Lauren Crump Latonia Holmes Jocelyn Lee Ching-ju Lu Michael E. Miller Mark A. Espeland Walter T. Ambrosius William B. Applegate Daniel P. Beavers Robert P. Byington Delilah Cook Curt D. Furberg Lea N. Harvin Leora Henkin M. Hepler Fang‐Chi Hsu Laura Lovato Wesley Roberson Julia Rushing Scott Rushing Cynthia L. Stowe Michael P. Walkup Don Hire W. Jack Rejeski Jeffrey A. Katula Peter H. Brubaker Shannon L. Mihalko Janine M. Jennings Evan C. Hadley Sergei Romashkan Kushang V. Patel Denise E. Bonds Mary Mcdermott Bonnie Spring Michelle E. Hauser Diana Kerwin Kathryn Domanchuk Rex Graff Alvito Rego Timothy S. Church Steven N. Blair Valerie H. Myers Ron Monce Nathan E. Britt Melissa Harris Ami Parks McGucken Ruben Rodarte Heidi K. Millet Catrine Tudor‐Locke Ben P. Butitta Sheletta G. Donatto Shannon Cocreham ­Abby C. King Cynthia M. Castro William L. Haskell Randall S. Stafford Leslie A. Pruitt Kathy Berra Veronica Yank Roger A. Fielding Miriam E. Nelson Sara C. Folta Edward M. Phillips Christine K. Liu Erica McDavitt Kieran F. Reid Dylan Kirn Evan Pasha Won S. Kim Vince E. Beard Eleni X. Tsiroyannis Cynthia Hau Todd M. Manini Marco Pahor Stephen D. Anton Susan Nayfield Thomas W. Buford Michael Marsiske Bhanuprasad Sandesara

10.1016/j.jamda.2016.10.001 article EN Journal of the American Medical Directors Association 2016-11-30

Our understanding of how multimorbidity progresses and changes is nascent.Assess among racially/ethnically diverse middle-aged older adults.Prospective cohort study using latent class analysis to identify combinations over 16 years, multinomial logistic models assess change relative baseline membership. Health Retirement Study respondents (age 51 y above) in 1998 followed through 2014 (N=17,297).Multimorbidity classes of: hypertension, heart disease, lung diabetes, cancer, arthritis, stroke,...

10.1097/mlr.0000000000001527 article EN Medical Care 2021-03-11

Introduction Multimorbidity may confer higher risk for cognitive decline than any single constituent disease. This study aims to identify distinct trajectories of impairment probability among middle-aged and older adults, assess the effect changes in mental-somatic multimorbidity on these trajectories. Methods Data from Health Retirement Study (1998–2016) were employed estimate group-based trajectory models identifying probability. Four time-varying combinations (somatic, stroke, depressive,...

10.1371/journal.pone.0303599 article EN cc-by PLoS ONE 2024-05-14

Abstract Background Racial/ethnic minoritized groups in the U.S. have higher prevalence of cardiometabolic multimorbidity and experience risk dementia. This study evaluates relationship between dementia onset according to racial/ethnic group a nationally representative cohort middle-aged older adults. Methods Data from Health & Retirement Study (1998-2018, N=7,960, mean baseline age 59.4 years) discrete-time survival models were used estimate differences onset, defined by Langa-Weir...

10.1093/gerona/glaf009 article EN other-oa The Journals of Gerontology Series A 2025-01-14

Genetic testing can advance cancer prevention if current screening behaviors improve. Increased prevalence of high-risk genotypes within specific religious groups, use venues for recruiting to genetic screening, and ethical-religious considerations argue exploring the role religiosity in forming decisions. This study uses theory reasoned action structural equation modeling test effects involvement, attitudes, knowledge, previous experience on intent-to-obtain a representative sample 1,824...

10.1177/1090198110389711 article EN Health Education & Behavior 2011-04-11

To evaluate latent heterogeneity in long-term trajectories of body weight older adults.

10.1177/0898264312468593 article EN Journal of Aging and Health 2012-12-21

Objective: The objective of this study is to (a) examine racial/ethnic differences in trajectories cognitive function and (b) evaluate the role education health behaviors (physical activity [PA] smoking) as mediators rate decline older adults. Method: Data for came from Health Retirement Study ( n = 3,424). Hierarchical linear models were used define trajectory between 2002 2008. Participants classified based on PA non–vigorously active, intermittent vigorously consistently active. Results:...

10.1177/0898264315620589 article EN Journal of Aging and Health 2015-12-31

Background Inter-relationships between multimorbidity and geriatric syndromes are poorly understood. This study assesses heterogeneity in joint trajectories of somatic disease, functional status, cognitive performance, depressive symptomatology. Methods We analyzed 16 years longitudinal data from the Health Retirement Study (HRS, 1998-2016) for n = 11,565 older adults (≥65 years) United States. Group-based mixture modeling identified latent clusters following similar across domains. Results...

10.1177/26335565221143012 article EN Journal of Multimorbidity and Comorbidity 2022-11-01

Obesity is increasingly prevalent among older adults, yet little known about the impact of health behaviors on trajectories body weight in this age group. We examined effect time-varying smoking, physical activity (PA), alcohol use, and changes thereof, 14-year (1992–2006) trajectory body- mass index (BMI) a cohort 10,314 adults from Health Retirements Study, aged 51–61 years at baseline. Hierarchical linear modeling (HLM) quantifies PA, use (user status, initiation cessation) intercept...

10.1093/gerona/gls073 article EN The Journals of Gerontology Series A 2012-03-29

We report the results of a study designed to assess and evaluate how law shapes public health system's preparedness activities. Based on 144 qualitative interviews conducted in nine states, we used model that compared objective legal environment with practitioners perceived laws. Most local emergency management professionals relied what they be rather than an adequate understanding requirements. Major reasons for gap include lack training difficulty obtaining clarification consistent advice...

10.1215/03616878-1538629 article EN Journal of Health Politics Policy and Law 2011-12-07
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