A5017226675- Pancreatic function and diabetes
- 3D Printing in Biomedical Research
- Pluripotent Stem Cells Research
- Microbial Metabolic Engineering and Bioproduction
- Tissue Engineering and Regenerative Medicine
- Innovative Microfluidic and Catalytic Techniques Innovation
- Cancer Cells and Metastasis
- Bacteriophages and microbial interactions
- Phytochemistry and Bioactivity Studies
- Additive Manufacturing and 3D Printing Technologies
- Studies on Chitinases and Chitosanases
- thermodynamics and calorimetric analyses
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- Biochemical and biochemical processes
- Click Chemistry and Applications
- melanin and skin pigmentation
- Organ Transplantation Techniques and Outcomes
- Antimicrobial Peptides and Activities
- Antimicrobial agents and applications
- Probiotics and Fermented Foods
- Diabetes Management and Research
- Diabetes and associated disorders
- Lipid Membrane Structure and Behavior
- Microbial Metabolism and Applications
Warsaw University of Technology
2017-2024
Polish Stem Cell Bank
2021-2022
Foundation for Polish Science
2020
In this study, we isolated 28 yeast strains from samples of plant material and fermented food evaluated the possibility efficient production 2‐phenylethanol (2‐PE) in organic waste‐based media supplemented with l‐phenylalanine (l‐Phe). We used whey, a by‐product milk processing, as base for media, either glucose or three by‐products sugar beet processing fermentable carbon source. Ten newly were capable producing over 2 g l−1 2‐PE through l‐Phe biotransformation batch mode standard medium....
Introduction 3D printing is being used more extensively in modern biomedicine. One of the problems selecting a proper crosslinking method bioprinted material. Amongst currently techniques we can distinguish: physical (e.g. Ca2+ and Sr2+) chemical crosslinking–the UV light causing biggest discussion. radiation selectively absorbed by DNA, mainly UV-B region but also (to some extent) UV-A UV-C regions. DNA excitement results typical photoproducts. The amount strand breaks may vary depending on...
Background: 3D bioprinting is the future of constructing functional organs. Creating a bioactive scaffold with pancreatic islets presents many challenges. The aim this paper to assess how process affects islet viability. Methods: BioX printer (Cellink), 600 μm inner diameter nozzles, and 3% (w/v) alginate cell carrier solution were used rat, porcine, human islets. Islets divided into control group (culture medium) 6 experimental groups (each subjected specific pressure between 15 100 kPa)....
Extracellular vesicles (EVs) are nanoparticles containing various bioactive cargos-e.g., proteins, RNAs, and lipids-that released into the environment by all cell types. They involved in, amongst other functions, intercellular communication. This article presents studies on EVs produced probiotic yeast Saccharomyces boulardii CNCM I-745. The size distribution concentration of in liquid culture were estimated. Moreover, S. tested for their cytotoxicity against three model human intestinal...
The development of an effective method melanocyte isolation and culture is necessary for basic clinical studies concerning skin diseases, including pigmentation disorders melanoma. In this paper, we describe a novel, non-enzymatic metastatic melanoma cell (along with the spontaneous spheroid creation) from or lymph node explants. based on selective harvesting melanocytes cells emigrating cultured Thereby, isolated retain their natural phenotypical features, such as expression tyrosinase...
One of the promising candidates for new antimicrobial agents is membrane-lytic compounds that kill microbes through cell membrane permeabilization, such as peptides (AMPs) and their synthetic mimics (SMAMPs). Although SMAMPs have been under investigation nearly 30 years, a few challenges must be addressed before they can reach clinical use. In this work, step-growth polymerization leading to already-known highly ionenes was redirected toward formation macrocyclic quaternary ammonium salts...
Abstract Violacein is a natural indole-derived purple pigment of microbial origin that has attracted attention for its remarkable biological properties. Due to poor solubility in aqueous media, most studies this use extracts the compound obtained with common solvents. also transported bacterial extracellular vesicles (EVs) and transferred via type carrier remains stable an environment. This paper first present in-depth study Janthinobacterium lividum EVs as violacein carriers. J. were...
Introduction: Pancreatic islet transplantation is one of the methods treating patients with T1D. However, for procedure to be successful, high quality implanted islets key importance a successful transplant. Following isolation, it has been shown that mainly β-cells undergo apoptosis due vascular loss and hypoxia. The cellular stresses which are subjected during isolation (for example disturbance cell-matrix relationship). Appropriate storage conditions insulated islands their functionality....